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Darvasamine

Reference work entry

CAS Registry Number: 36284-98-7 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Quinolizidine Alkaloids

Biological sources: Leontice alberti, L. darwasica

C15H24N2O: 248.1889

Mp: 102°C (Et2O), 355°C (hydrochloride), 265°C (dec., perchlorate), 305°C (dec., methiodide), 297°C (hydroiodide) [1]

[α]D +72° (c 0.4, EtOH) [1]

Solubility: very sol. CHCl3, EtOH, MeOH, Me2CO, H2O; spar. sol. Et2O, pet. ether [1]

IR: 3000–2800, 1645, 1460, 1420, 1350, 1310 [1]

MSm/z: 248(M+, 58), 247(100), 219, 205, 191, 177, 162, 150, 138, 136, 98, 83, 55 [1]

1H NMR: 4.45(1H, q, J = 13.5, 3, He-17) [1]

Stereochemistry is questionable: [2,3]

ORD: [4]

References

  1. 1.
    A. Zunnunzhanov, S. Iskandarov, S.Yu. Yunusov, Chem. Nat. Comp. 7, 838 (1971)CrossRefGoogle Scholar
  2. 2.
    A. S. Sadykov, Izv. AN SSSR Ser. Khim. 2432 (1983)Google Scholar
  3. 3.
    B.T. Ibragimov, G.N. Tishchenko, Yu.K. Kushmuradov, S.A. Talipov, T.F. Aripov, Chem. Nat. Comp. 18, 66 (1982). revCrossRefGoogle Scholar
  4. 4.
    A. Zunnunzhanov, S. Iskandarov, S.Yu. Yunusov, Chem. Nat. Comp. 10, 371 (1974)CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2013

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