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Aloperine

Reference work entry

CAS Registry Number: 56293-29-9 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Quinolizidine Alkaloids

Biological sources: Leptorhabdos parviflora, Sophora alopecuroides

C15H24N2: 232.194

Mp: 72°C (petr. ether), 265°C (dihydrochloride), 208°C (hydrochloride) [1]

[α]D +82° (c 0.854, EtOH)

MSm/z: 232(M+), 203, 189, 174, 148, 134, 98, 97, 96, 84, 83 [1]

1H NMR: 1.79(1H, H-7), 2.26(1H, 2J15 = 13.5, J15,13e = 2.2, J15,14e = 2.2, He-15), 2.45(1H, q, J = 3.4, 12, Ha-10), 2.66(1H, J13,14a = 9, 2J13 = 12, Ha-13), 2.86(1H, q, J = 5.2, 12, He-10), 3.08(1H, 2J13 = 12, He-13), 3.11(1H, d, J = 6.3, H-11), 5.40(1H, d, J7,17 = 6.5, H-17) [1]

X-ray: [2]

Abs. Conf.: 6R7R9R11S [2]

HPLC, GC: [3]

Pharm./Biol.: Stimulating action. Raises arterial pressure and stimulates respiration [4]

References

  1. 1.
    O.N. Tolkachev, T.E. Monakhova, V.I. Sheichenko, V.S. Kabanov, O.G. Fesenko, N.F. Proskurnina, Chem. Nat. Comp. 11, 29 (1975)CrossRefGoogle Scholar
  2. 2.
    A.D. Brosius, J.W. Ziller, Q. Zhang, Acta Cryst. C. 53, 1510 (1997)CrossRefGoogle Scholar
  3. 3.
    X. Chen, C.Q. Yi, X.Q. Yang, X. Wang, J. Chromatogr. B 812, 149 (2004)Google Scholar
  4. 4.
    T.E. Monakhova, Author’s Abstract of Candidate’s Dissertation, Moscow, 1975Google Scholar

Copyright information

© Springer Science+Business Media New York 2013

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