Encyclopedia of Systems Biology

2013 Edition
| Editors: Werner Dubitzky, Olaf Wolkenhauer, Kwang-Hyun Cho, Hiroki Yokota

Orthologs

Reference work entry
DOI: https://doi.org/10.1007/978-1-4419-9863-7_955

Definition

Orthologs are genes in two or more species that evolved from a common ancestral gene by speciation. Normally, orthologs retain the same function in the course of evolution. Ortholog identification is used for reliable prediction of gene function in newly sequenced genomes.

Copyright information

© Springer Science+Business Media, LLC 2013

Authors and Affiliations

  1. 1.G.N. Ramachandran Knowledge Centre for Genome InformaticsInstitute of Genomics and Integrative BiologyDelhiIndia