Organism State, Lymphocyte
Normal healthy individuals: The age is a factor that influences cell dynamics and selection processes. Ontogeny and aging are periods of construction and regression of the immune system and lymphocyte repertoires, with relative immunodeficiency.
Immunodeficient individuals, for which the immunodeficiency origin could be related to:
Genetic: either with partial T-cell immunodeficiency (e.g., athymic nude mice, DiGeorge syndrome in infants, CD3- or TCR-related deficiency) or B-cell...