Ontology Analysis of Biological Networks
Ontology analysis of biological networks is the strategy to discover the biological implications via identifying significantly enriched annotated ontology terms in networks or subnetworks.
According to the accumulation of different types of experimental data and prior knowledge, more and more biological networks are constructed to discover the underlying mechanisms of cell in a system level. At the same time, the demand for strategies to analyze and mine biological meanings from these resulting networks increases quickly. Function enrichment analysis is an important way to fill the requirement. An efficient way to accurately describe function of gene is to use the ontology structure ( ontology) of GO ( Gene Ontology) terms.
The Importance of Ontology Analysis
Ontologywhich is a formal representation of knowledge is one of the most popular words in information science recently. To uniformly represent gene and gene product across databases and species,...