Encyclopedia of Systems Biology

2013 Edition
| Editors: Werner Dubitzky, Olaf Wolkenhauer, Kwang-Hyun Cho, Hiroki Yokota

Overdetermined System

Reference work entry
DOI: https://doi.org/10.1007/978-1-4419-9863-7_1488


A system of linear equations is overdetermined if the number of equations is larger than the number of unknowns. If the number of equations is smaller than the number of unknowns, the system is underdetermined. In a system of linear equations representing a metabolic model, the equations are the metabolite balances and the unknowns are the metabolic fluxes through the intracellular reactions.


  1. Stephanopoulos G, Aristidou A, Nielsen J (1998) Metabolic Engineering: Principles and Methodologies. Academic Press, San Diego, ISBN: 978-0-12-666260-3, Chapter 8.Google Scholar

Copyright information

© Springer Science+Business Media, LLC 2013

Authors and Affiliations

  1. 1.Department of Microbial and Cellular Sciences, Faculty of Health and Medical SciencesUniversity of SurreyGuildfordUK