Operon Theory is the concept of gene regulation proposed by François Jacob and Jacques Monod (1961). An operon is a group of structural genes whose expression is coordinated by an operator. The repressor encoded by a regulatory gene binds to the operator and represses the transcription of operon. In the presence of inducer, the repressor is inactivated and dissociates from operator to express the operon. Thus, the expression of the operon is controlled by a cis-acting operator and by a trans-acting repressor.
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