Optimal Dynamic Experiments
Dynamic experiments refer to the lab measurements performed under time-varying stimulation conditions. Optimal dynamic experiments are those that have been designed to attend to a given optimality criteria (Walter and Pronzato 1997). The optimal design problem is formulated as a dynamic optimization ( Biochemical Systems Optimization Through Mathematical Programming) problem where the objective is to compute the experimental setup that maximizes (or minimizes) a performance index subject to the system dynamics, mathematical representation (model or models), and the experimental constraints (Balsa-Canto et al. 2010).
Definition: Model Candidates
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