Definition
Optimization algorithms for metabolite production are referred to in silico approaches intended to increase or optimize the synthesis of valuable products from the industrial perspective through using microorganisms. It generally departs from the metabolic reconstruction of the microorganism responsible for synthesizing such products. Due to the fact that the organisms display a dissimilar objective function compared to the industrial interest, optimization platforms are usually implemented based on bi-level programming frameworks where two objective functions are satisfied: ours and the organism.
Characteristics
Biotechnology research is partly aimed to decrease costs when designing bioprocess for producing high valuable products. This is reached through elaborating a parallel analysis of all factors influencing the process economics. Generally, biotransformation constitutes one of...
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Barrios, A.F.G., Restrepo, S., Pinzón Velasco, A.M. (2013). Optimization Algorithms for Metabolites Production. In: Dubitzky, W., Wolkenhauer, O., Cho, KH., Yokota, H. (eds) Encyclopedia of Systems Biology. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-9863-7_1172
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DOI: https://doi.org/10.1007/978-1-4419-9863-7_1172
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4419-9862-0
Online ISBN: 978-1-4419-9863-7
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