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Biosensors, Electrochemical

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Encyclopedia of Applied Electrochemistry

Introduction

In early 2000, two Divisions of the International Union of Pure and Applied Chemistry (IUPAC) prepared recommendations on the definition, classification, and nomenclature related to electrochemical biosensors; these recommendations have been then extended to other types of biosensors. Following these IUPAC recommendations, “a biosensor is defined as a self-contained integrated device, which is capable of providing specific quantitative or semi-quantitative analytical information using a biological recognition element (biochemical receptor) which is retained in direct spatial contact with an electrochemical transduction element. Because of their ability to be repeatedly calibrated, a biosensor should be clearly distinguished from a bioanalytical system, which requires additional processing steps, such as reagent addition” [1].

Another important concept was introduced, some years later, by Turner and Newman in [2]; they referred to a biosensor as “a compact analytical...

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References

  1. Thevenot DR, Toth K, Durst RA et al (2001) Electrochemical biosensors: recommended definitions and classification. Biosens Bioelectron 16:121–131

    CAS  Google Scholar 

  2. Newman JD, Tigwell LJ, Turner APF et al (2004) Biosensors – a clearer view. Cranfield University Publication, UK

    Google Scholar 

  3. Labuda J, Oliveira Brett AM, Evtugyn G, Fojta M, Mascini M, Ozsoz M, Palchetti I, Paleček E, Wang J (2010) Electrochemical nucleic acid-based biosensors: concepts, terms, and methodology (IUPAC technical report). Pure Appl Chem 82:1161–1187

    CAS  Google Scholar 

  4. Clark LC (1956) Monitor and control of blood and tissue oxygen tensions. Trans Am Soc Artif Intern Organs 2:41–48

    Google Scholar 

  5. Clark LC, Lyons C (1962) Electrode systems for continuous monitoring cardiovascular surgery. Ann N Y Acad Sci 102:29–45

    CAS  Google Scholar 

  6. Updike SJ, Hicks GP (1967) The enzyme electrode. Nature 214:986–988

    CAS  Google Scholar 

  7. Eggins BR (2002) Chemical sensors and biosensors. Wiley, Chichester

    Google Scholar 

  8. Cagnini A, Palchetti I, Lionti I, Mascini M, Turner APF (1995) Disposable ruthenized screen-printed biosensors for pesticides monitoring. Sens Actuators B 24–25:85–89

    Google Scholar 

  9. Palchetti I, Cagnini A, Del Carlo M, Coppi C, Mascini M, Turner APF (1997) Determination of anticholinesterase pesticides in real samples using a disposable biosensor. Anal Chim Acta 337:315–321

    CAS  Google Scholar 

  10. Hernandez S, Palchetti I, Mascini M (2000) Determination on anticholinesterase activity for pesticides monitoring using acetylthiocholine sensor. Int J Environ Anal Chem 78:3–4

    Google Scholar 

  11. Mascini M, Palchetti I (2001) Electrochemical biosensor for evaluation of contaminants in food for quality improvement. Arch Ind Hyg Toxicol 52:49–59

    CAS  Google Scholar 

  12. Cagnini A, Palchetti I, Mascini M, Turner APF (1995) Ruthenised screen-printed choline oxidase-based biosensors for measurement of anticholinesterase activity. Mikrochim Acta 121:155–166

    CAS  Google Scholar 

  13. Laschi S, Ogończyk D, Palchetti I, Mascini M (2007) Evaluation of pesticide-induced acetylcholinesterase inhibition by means of disposable carbon-modified electrochemical biosensors. Enzyme Microb Technol 40:485–489

    CAS  Google Scholar 

  14. Rogers KR (2006) Recent advances in biosensor techniques for environmental monitoring. Anal Chim Acta 568:222

    CAS  Google Scholar 

  15. Mascini M, Palchetti I (eds) (2011) Nucleic acid biosensors for environmental pollution monitoring. RSC Publishing, London. ISBN 978-1-84973-131-7

    Google Scholar 

  16. Laschi S, Miranda-Castro R, González-Fernández E, Palchetti I, Reymond F, Rossier JS, Marrazza G (2010) A new gravity-driven microfluidic-based electrochemical assay coupled to magnetic beads for nucleic acid detection. Electrophoresis 31:1–10

    Google Scholar 

  17. Centi S, Bonel Sanmartin L, Tombelli S, Palchetti I, Mascini M (2009) Detection of C reactive protein (CRP) in serum by an electrochemical aptamer-based sandwich assay. Electroanalysis 21:1309–1315

    CAS  Google Scholar 

  18. Laschi S, Palchetti I, Marrazza G, Mascini M (2009) Enzyme-amplified electrochemical hybridization assay based on PNA, LNA and DNA probe-modified micro-magnetic beads. Bioelectrochemistry 76:214–220

    CAS  Google Scholar 

  19. Berti F, Laschi S, Palchetti I, Rossier J, Reymond F, Mascini M, Marrazza G (2009) Microfluidic-based electrochemical genosensor coupled to magnetic beads for hybridization detection. Talanta 77:971–978

    CAS  Google Scholar 

  20. Centi S, Messina G, Tombelli S, Palchetti I, Mascini M (2008) Different approaches for the detection of thrombin by an electrochemical aptamer-based assay coupled to magnetic beads. Biosens Bioelectron 23:1602–1609

    CAS  Google Scholar 

  21. Centi S, Silva E, Laschi S, Palchetti I, Mascini M (2007) Polychlorinated biphenyls (PCBs) detection in milk samples by an electrochemical magneto-immunosensor (EMI) coupled to solid phase extraction (SPE) and disposable low density arrays. Anal Chim Acta 594:9–16

    CAS  Google Scholar 

  22. Bettazzi F, Lucarelli F, Palchetti I, Berti F, Marrazza G, Mascini M (2008) Disposable electrochemical DNA-array for PCR amplified detection of hazelnut allergens in foodstuff. Anal Chim Acta 614:93–102

    CAS  Google Scholar 

  23. Guilbault G, Montalvo J (1969) A urea specific enzyme electrode. J Am Chem Soc 9:2164–2169

    Google Scholar 

  24. Katz E, Willner I (2003) Probing biomolecular interactions at conductive and semiconductive surfaces by impedance spectroscopy: routes to impedimetric immunosensors, DNA-sensors, and enzyme biosensors. Electroanalysis 15:913–947

    CAS  Google Scholar 

  25. Daniels JS, Pourmand N (2007) Label-free impedance biosensors: opportunities and challenges. Electroanalysis 19:1239–1257

    CAS  Google Scholar 

  26. Katz E, Willner I, Wang J (2004) Electroanalytical and bioelectroanalytical systems based on metal and semiconductor nanoparticles. Electroanalysis 16:119–144

    Google Scholar 

  27. Palchetti I, Mascini M (2012) Electrochemical nanomaterial-based nucleic acid aptasensors. Anal Bioanal Chem 402:3103–3114. doi:10.1007/s00216-012-5769-1

    CAS  Google Scholar 

  28. Batchelor-McAuley C, Dickinson EJF, Rees NV, Toghill KE, Compton RG (2012) Anal Chem 84:669–684. doi:org/10.1021/ac2026767

    Google Scholar 

  29. Sinensky AK, Belcher AM (2007) Label-free and high-resolution protein/DNA nanoarray analysis using Kelvin probe force microscopy. Nat Nanotechnol 2:653–659. doi:10.1038/nnano.2007.293

    CAS  Google Scholar 

  30. Bard AJ, Mirkin MV (2001) Scanning electrochemical microscopy. Marcel Dekker, New York

    Google Scholar 

  31. Turcu F, Schulte A, Hartwich G, Schuhmann W (2004) Label-free electrochemical recognition of DNA hybridization by means of modulation of the feedback current in SECM. Angew Chem Int Ed 43:3482–3485

    CAS  Google Scholar 

  32. Palchetti I, Laschi S, Marrazza G, Mascini M (2007) Electrochemical imaging of localized sandwich DNA hybridization using scanning electrochemical microscopy. Anal Chem 79:7206–7213

    CAS  Google Scholar 

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Authors and Affiliations

  1. Dipartimento di Chimica “Ugo Schiff”, Università degli Studi di Firenze, Via della Lastruccia 3, 50019, Sesto Fiorentino, Firenze, Italy

    Marco Mascini & Ilaria Palchetti

Authors
  1. Marco Mascini
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  2. Ilaria Palchetti
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Corresponding author

Correspondence to Marco Mascini .

Editor information

Editors and Affiliations

  1. Eppstein, Germany

    Gerhard Kreysa

  2. Yokohama National University, Fac. Engineering, Yokohama, Japan

    Ken-ichiro Ota

  3. Case Western Reserve University, Cleveland, OH, USA

    Robert F. Savinell

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Mascini, M., Palchetti, I. (2014). Biosensors, Electrochemical. In: Kreysa, G., Ota, Ki., Savinell, R.F. (eds) Encyclopedia of Applied Electrochemistry. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-6996-5_252

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