Encyclopedia of Behavioral Medicine

2013 Edition
| Editors: Marc D. Gellman, J. Rick Turner

Phenotype

  • Jeanette McCarthy
Reference work entry
DOI: https://doi.org/10.1007/978-1-4419-1005-9_713

Definition

The term phenotype refers to an organism’s outward appearance and characteristics. This contrasts with the individual’s genotype, the set of alleles that an offspring inherits from both parents. In the behavioral sciences, including Behavioral Medicine, the fundamental issue of heredity is the extent to which differences in genotype account for differences in phenotype, i.e., observed differences among individuals (Plomin, DeFries, McClearn, & Rutter, 1997).

In contrast to single-gene disorders such as Huntington’s disease and phenylketonuria (PKU), complex dimensions, disorders, and conditions of clinical concern in Behavioral Medicine are influenced by heredity, but not by one gene alone. Multiple genes are typically involved, and so too are multiple environmental influences, and phenotypes are often the result of the combined effects of both genotype and environmental factors.

Cross-References

References and Readings

  1. Plomin, R., DeFries, J. C., McClearn, G. E., & Rutter, M. (1997). Behavioral genetics (3rd ed.). New York: W.H. Freeman and Company.Google Scholar

Copyright information

© Springer Science+Business Media, New York 2013

Authors and Affiliations

  1. 1.Community and Family MedicineDuke University Medical CenterDurhamUSA