Skip to main content
SpringerLink
Log in
Book cover

Image-Guided Cancer Therapy pp 631–642Cite as

Cryoablation of Bone Tumors

  • Reference work entry
  • First Online:

  • 1448 Accesses

Abstract

Bone and soft tissue metastases can give rise to complications including pain, decreased quality of life, and decreased mobility. The standard palliative treatment for patients with metastatic disease is external beam radiation therapy. When this fails to give pain relief or when relief is transient, analgesics (opioids and nonsteroidal anti-inflammatory drugs) are typically optimized although inadequate pain relief or side effects are often present for these patients. Image-guided percutaneous cryoablation of focal painful metastases has emerged as an effective focal treatment for patients with painful metastatic disease. This treatment offers clinically significant reduction of pain, an improvement in their quality of life, and reduction in the use of analgesic medications by these patients.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   269.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD   379.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  1. Nielsen OS, Munro AJ, Tannock IF. Bone metastases: pathophysiology and management policy. J Clin Oncol. 1991;9:509–24.

    Article  CAS  PubMed  Google Scholar 

  2. Mercadante S. Malignant bone pain: pathophysiology and treatment. Pain. 1997;69:1–18.

    Article  CAS  PubMed  Google Scholar 

  3. Tong D, Gillick L, Hendrickson FR. The palliation of symptomatic osseous metastases: final results of the study by the Radiation Therapy Oncology Group. Cancer. 1982;50(5):893–9.

    Article  CAS  PubMed  Google Scholar 

  4. Massie MJ, Holland JC. The cancer patient with pain: psychiatric complications and their management. J Pain Symptom Manage. 1992;7:99–109.

    Article  CAS  PubMed  Google Scholar 

  5. Spiegel D, Sands S, Koopman C. Pain and depression in patients with cancer. Cancer. 1994;74:2570–8.

    Article  CAS  PubMed  Google Scholar 

  6. Jeremic B, Shibamoto Y, Acimovic L, et al. A randomized trial of three single-dose radiation therapy regimens in the treatment of metastatic bone pain. Int J Radiat Oncol Biol Phys. 1998;42(1):161–7.

    Article  CAS  PubMed  Google Scholar 

  7. Price P, Hoskin PJ, Easton D, Austin D, Palmer SG, Yarnold JR. Prospective randomised trial of single and multifraction radiotherapy schedules in the treatment of painful bony metastases. Radiother Oncol. 1986;6:247–55.

    Article  CAS  PubMed  Google Scholar 

  8. Cole DJ. A randomized trial of a single treatment versus conventional fractionation in the palliative radiotherapy of painful bone metastases. Clin Oncol (R Coll Radiol). 1989;1:59–62.

    Article  CAS  Google Scholar 

  9. Gaze MN, Kelly CG, Kerr GR, et al. Pain relief and quality of life following radiotherapy for bone metastases: a randomised trial of two fractionation schedules. Radiother Oncol. 1997;45:109–16.

    Article  CAS  PubMed  Google Scholar 

  10. Steenland E, Leer JW, van Houwelingen H, et al. The effect of a single fraction compared to multiple fractions on painful bone metastases: a global analysis of the Dutch Bone Metastasis Study. Radiother Oncol. 1999;52(2):101–9.

    Article  CAS  PubMed  Google Scholar 

  11. Gangi A, Kastler B, Klinkert A, Dietemann JL. Injection of alcohol into bone metastases under CT guidance. J Comput Assist Tomogr. 1994;18:932–5.

    Article  CAS  PubMed  Google Scholar 

  12. Gröenemeyer DH, Schirp S, Gevargez A. Image-guided percutaneous thermal ablation of bone tumors. Acad Radiol. 2002;9:467–77.

    Article  PubMed  Google Scholar 

  13. Dupuy DE, Safran H, Mayo-Smith WW, Goldberg SN. Radiofrequency ablation of painful osseous metastatic disease. Radiology. 1998;209(P):389.

    Google Scholar 

  14. Callstrom MR, Charboneau JW, Goetz MP, et al. Painful metastases involving bone: feasibility of percutaneous CT- and US-guided radio-frequency ablation. Radiology. 2002;224(1):87–97.

    Article  PubMed  Google Scholar 

  15. Goetz MP, Callstrom MR, Charboneau JW, et al. Percutaneous image-guided radiofrequency ablation of painful metastases involving bone: a multicenter study. J Clin Oncol. 2004;22(2):300–6.

    Article  PubMed  Google Scholar 

  16. Beland MD, Dupuy DE, Mayo-Smith WW. Percutaneous cryoablation of symptomatic extraabdominal metastatic disease: preliminary results. AJR Am J Roentgenol. 2005;184(3):926–30.

    Article  PubMed  Google Scholar 

  17. Callstrom MR, Charboneau JW, Goetz MP, et al. Image-guided ablation of painful metastatic bone tumors: a new and effective approach to a difficult problem. Skeletal Radiol. 2006;35(1):1–15.

    Article  PubMed  Google Scholar 

  18. Dupuy DE, Liu D, Hartfeil D, et al. Percutaneous radiofrequency ablation of painful osseous metastases: a multicenter American College of Radiology Imaging Network trial. Cancer. 2010;116(4):989–97.

    Article  PubMed  PubMed Central  Google Scholar 

  19. Callstrom MR, Atwell TD, Charboneau JW, et al. Painful metastases involving bone: percutaneous image-guided cryoablation–prospective trial interim analysis. Radiology. 2006;241(2):572–80.

    Article  PubMed  Google Scholar 

  20. Sabharwal T, Katsanos K, Buy X, Gangi A. Image-guided ablation therapy of bone tumors. Semin Ultrasound CT MR. 2009;30(2):78–90.

    Article  PubMed  Google Scholar 

  21. Sabharwal T, Salter R, Adam A, Gangi A. Image-guided therapies in orthopedic oncology. Orthop Clin North Am. 2006;37(1):105-+.

    Article  PubMed  Google Scholar 

  22. Callstrom MR, Kurup AN. Percutaneous ablation for bone and soft tissue metastases–why cryoablation? Skeletal Radiol. 2009;38(9):835–9.

    Article  PubMed  Google Scholar 

  23. Callstrom MR, York JD, Gaba RC, et al. Research reporting standards for image-guided ablation of bone and soft tissue tumors. J Vasc Interv Radiol. 2009;20(12):1527–40.

    Article  PubMed  Google Scholar 

  24. Rybak LD. Fire and ice: thermal ablation of musculoskeletal tumors. Radiol Clin North Am. 2009;47(3):455–69.

    Article  PubMed  Google Scholar 

  25. Chosy SG, Nakada SY, Lee Jr FT, Warner TF. Monitoring renal cryosurgery: predictors of tissue necrosis in swine. J Urol. 1998;159(4):1370–4.

    Article  CAS  PubMed  Google Scholar 

  26. Dodd 3rd GD, Frank MS, Aribandi M, Chopra S, Chintapalli KN. Radiofrequency thermal ablation: computer analysis of the size of the thermal injury created by overlapping ablations. AJR Am J Roentgenol. 2001;177(4):777–82.

    Article  PubMed  Google Scholar 

  27. Mohler DG, Chiu R, McCall DA, Avedian RS. Curettage and cryosurgery for low-grade cartilage tumors is associated with low recurrence and high function. Clin Orthop Relat Res. 2010;468(10):2765–73.

    Article  PubMed  PubMed Central  Google Scholar 

  28. Meller I, Weinbroum A, Bickels J, et al. Fifteen years of bone tumor cryosurgery: a single-center experience of 440 procedures and long-term follow-up. Eur J Surg Oncol. 2008;34(8):921–7.

    Article  CAS  PubMed  Google Scholar 

  29. Grobmyer SR, Maki RG, Demetri GD, et al. Neo-adjuvant chemotherapy for primary high-grade extremity soft tissue sarcoma. Ann Oncol. 2004;15(11):1667–72.

    Article  CAS  PubMed  Google Scholar 

  30. Bickels J, Meller I, Shmookler BM, Malawer MM. The role and biology of cryosurgery in the treatment of bone tumors. A review. Acta Orthop Scand. 1999;70(3):308–15.

    Article  CAS  PubMed  Google Scholar 

  31. Ahlmann ER, Falkinstein Y, Fedenko AN, Menendez LR. Cryoablation and resection influences patient survival for soft tissue sarcomas: impact on survivorship and local recurrence. Clin Orthop Relat Res. 2007;459:174–81.

    Article  PubMed  Google Scholar 

  32. Kujak JL, Liu PT, Johnson GB, Callstrom MR. Early experience with percutaneous cryoablation of extra-abdominal desmoid tumors. Skeletal Radiol. 2010;39(2):175–82.

    Article  PubMed  Google Scholar 

  33. Wu B, Xiao YY, Zhang X, Zhao L, Carrino JA. CT-guided percutaneous cryoablation of osteoid osteoma in children: an initial study. Skeletal Radiol. 2011;40:1303–10.

    Article  PubMed  Google Scholar 

  34. Liu GR, Gao PY, Lin Y, et al. Brain magnetic resonance elastography on healthy volunteers: a safety study. Acta Radiol. 2009;50(4):423–9.

    Article  PubMed  Google Scholar 

  35. Sewell P, Jackson M, Dhillon G. Percutaneous MRI guided cryosurgery of bone tumors. Radiology. 2002;225(P):514.

    Google Scholar 

  36. Tuncali K, Morrison PR, Winalski CS, et al. MRI-guided percutaneous cryotherapy for soft-tissue and bone metastases: initial experience. AJR Am J Roentgenol. 2007;189(1):232–9.

    Article  PubMed  Google Scholar 

  37. Lessard AM, Gilchrist J, Schaefer L, Dupuy DE. Palliation of recurrent Ewing sarcoma of the pelvis with cryoablation and somatosensory-evoked potentials. J Pediatr Hematol Oncol. 2009;31(1):18–21.

    Article  PubMed  Google Scholar 

  38. Ullrick SR, Hebert JJ, Davis KW. Cryoablation in the musculoskeletal system. Curr Probl Diagn Radiol. 2008;37(1):39–48.

    Article  PubMed  Google Scholar 

  39. Daut RL, Cleeland CS, Flanery RC. Development of the wisconsin brief pain questionnaire to assess pain in cancer and other diseases. Pain. 1983;17:197–210.

    Article  CAS  PubMed  Google Scholar 

  40. Cleeland CS, Gonin R, Hatfield AK, et al. Pain and its treatment in outpatients with metastatic cancer. N Engl J Med. 1994;330:592–6.

    Article  CAS  PubMed  Google Scholar 

  41. Farrar JT, Young Jr JP, LaMoreaux L, Werth JL, Poole RM. Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale. Pain. 2001;94:149–58.

    Article  CAS  PubMed  Google Scholar 

  42. Thacker PG, Callstrom MR, Curry TB, et al. Palliation of painful metastatic disease involving bone with image-guided treatment: comparison of patients immediate response to radiofrequency ablation and cryoablation. AJR Am J Roentgenol. 2011;197(2):510–5.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiology, Mayo Clinic, 200 1st Street SW, Rochester, MN, 55905, USA

    Matthew Callstrom

Authors
  1. Matthew Callstrom
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Matthew Callstrom .

Editor information

Editors and Affiliations

  1. The Warren Alpert Medical School of Brown University, Department of Diagnostic Imaging Rhode Island Hospital, Providence, Rhode Island, USA

    Damian E. Dupuy

  2. Department of Surgery and Radiology Memorial Sloan-Kettering Cancer Center, New York, New York, USA

    Yuman Fong

  3. McMullen Consulting, LLC, Surprise, Arizona, USA

    William N. McMullen

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer Science+Business Media New York

About this entry

Cite this entry

Callstrom, M. (2013). Cryoablation of Bone Tumors. In: Dupuy, D., Fong, Y., McMullen, W. (eds) Image-Guided Cancer Therapy. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-0751-6_45

Download citation

  • DOI: https://doi.org/10.1007/978-1-4419-0751-6_45

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4419-0750-9

  • Online ISBN: 978-1-4419-0751-6

  • eBook Packages: MedicineReference Module Medicine

Publish with us

Policies and ethics

Search

Navigation