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Benign Diseases of the Endometrium

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Book cover Blaustein’s Pathology of the Female Genital Tract

Abstract

The endometrium and the myometrium are of mesodermal origin and are formed secondary to fusion of the müllerian (paramesonephric) ducts between the 8th and 9th postovulatory weeks. The cervix is generally considered to be of müllerian origin, although it has been claimed that its mucous membrane is derived from the urogenital sinus; however, the exact contribution of müllerian and sinus tissue to the cervix remains uncertain [47]. Until the 20th week of gestation, the endometrium consists of a single layer of columnar epithelium supported by a thick layer of fibroblastic stroma. After the 20th gestational week, the surface epithelium invaginates into the underlying stroma, forming glandular structures that extend toward the underlying myometrium. At birth, the uterus, which is made up of the uterine corpus and uterine cervix, measures approximately 4 cm in length, the majority of which is made up of the cervix. The endometrium measures less than 0.5 mm in thickness, and the surface and glands are lined by a low columnar to cuboidal epithelium devoid of either proliferative or secretory activity, which resembles the inactive endometrium of postmenopausal women.

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Authors and Affiliations

  1. Department of Pathology, Royal Group of Hospitals Trust, Grosvenor Road, Belfast, BT12 6BA, Northern Ireland

    W. Glenn McCluggage

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  1. W. Glenn McCluggage
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Correspondence to W. Glenn McCluggage .

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Editors and Affiliations

  1. Departments of Gynecology, Obstetrics, Pathology and Oncology, The Johns Hopkins University School of Medicine and Director of Gynecologic Pathology, The Johns Hopkins Hospital, 401 N. Broadway, Weinberg Building Room 2242, Baltimore, MD, 21231, USA

    Robert J. Kurman (Richard W. TeLinde Distinguished Professor of Gynecologic Pathology) (Richard W. TeLinde Distinguished Professor of Gynecologic Pathology)

  2. Department of Pathology and Laboratory Medicine, Weill Cornell Medical College and New York Presbyterian Hospital, 525 East 68th Street, Starr 1015, New York, NY, 10065, USA

    Lora Hedrick Ellenson

  3. Department of Pathology, Johns Hopkins University School of Medicine, 401 N. Broadway, Weinberg Building 2242, Baltimore, MD, 21231, USA

    Brigitte M. Ronnett

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McCluggage, W.G. (2011). Benign Diseases of the Endometrium. In: Kurman, R.J., Ellenson, L.H., Ronnett, B.M. (eds) Blaustein’s Pathology of the Female Genital Tract. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-0489-8_7

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  • DOI: https://doi.org/10.1007/978-1-4419-0489-8_7

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