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Metastatic Tumors of the Ovary

  • Reference work entry
Blaustein’s Pathology of the Female Genital Tract

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Abstract

Tumors that spread to the ovary from elsewhere are an important group of ovarian neoplasms because the misinterpretation of cases encountered as surgical pathology specimens may have significant adverse consequences for the patient. The spread may be from adjacent sites by direct local extension or from distant extragenital sites [27, 44, 61, 66, 90, 94, 111, 145, 152, 155, 161, 162]. The latter tumors are truly metastatic, whereas the designation “metastatic” is sometimes not used for those that are secondary from local sites. However, for simplicity, this discussion includes spread to the ovary from all sites.

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References

  1. Abdul-Hafeez M, Akhtar M, Aqeel HSB, Kidess EA (1987) Placental site trophoblastic tumor: report of a case with review of literature. Ann Saudi Med 7:340–344

    Google Scholar 

  2. Abu-Rustum NR, Barakat RR, Curtin JP (1997) Ovarian and uterine disease in women with colorectal cancer. Gynecol Oncol 89:85–87

    Article  CAS  Google Scholar 

  3. Acosta-Sison H (1958) The relative frequency of various anatomic sites as the point of first metastasis in 32 cases of chorionepithelioma. Am J Obstet Gynecol 75:1149–1152

    PubMed  CAS  Google Scholar 

  4. Agoff SN, Lamps LW, Philip AT, Amin MB, Schmidt RA, True LD, Folpe AL (2000) Thyroid transcription factor-1 is expressed in extrapulmonary small cell carcinomas but not in other extrapulmonary neuroendocrine tumors. Mod Pathol 13:238–242

    Article  PubMed  CAS  Google Scholar 

  5. Amorn Y, Knight WA (1978) Primary linitis plastica of the colon: report of two cases and review of the literature. Cancer (Phila) 41:2420–2425

    Article  CAS  Google Scholar 

  6. Baker PM, Clement PB, Young RH (2005) Malignant peritoneal mesothelioma in women. A study of 75 cases with emphasis on their morphologic spectrum and differential diagnosis. Am J Clin Pathol 123:724–737

    Article  PubMed  Google Scholar 

  7. Baker PM, Oliva E (2004) Immunohistochemistry as a tool in the differential diagnosis of ovarian tumors: an update. Int J Gynecol Pathol 24:39–55

    Google Scholar 

  8. Beck RP, Latour JPA (1963) Necropsy reports on 36 cases of endometrial carcinoma. Am J Obstet Gynecol 85:307–311

    PubMed  CAS  Google Scholar 

  9. Berezowski K, Stastny JF, Kornstein MJ (1996) Cytokeratins 7 and 20 and carcinoembryonic antigen in ovarian and colonic carcinoma. Mod Pathol 9:426–429

    PubMed  CAS  Google Scholar 

  10. Bhargava R, Beriwal S, Dabbs DJ (2007) Mammaglobin vs GCDFP-15. An immunohistologic validation survey for sensitivity and specificity. Am J Clin Pathol 127:103–113

    Article  PubMed  CAS  Google Scholar 

  11. Birnkrant A, Sampson J, Sugarbaker PH (1986) Ovarian metastasis from colorectal cancer. Dis Colon Rectum 29:767–771

    Article  PubMed  CAS  Google Scholar 

  12. Brogioni S, Viacava P, Tomisti L, Martino E, Macchia E (2007) A special case of bilateral metastases in a woman with papillary carcinoma of the thyroid. Exp Clin Endocrinol Diabetes 115:397–400

    Article  PubMed  CAS  Google Scholar 

  13. Brown BL, Scharifker DA, Gordon R, Deppe GG, Cohen CJ (1980) Bronchial carcinoid tumor with ovarian metastasis. A light microscopic and ultrastructural study. Cancer 46:543–546

    Article  PubMed  CAS  Google Scholar 

  14. Bullon A, Arseneau J, Prat J, Young RH, Scully RE (1981) Tubular Krukenberg tumor. A problem in histopathologic diagnosis. Am J Surg Pathol 5:225–232

    Article  PubMed  Google Scholar 

  15. Bunker ML (1959) The terminal findings in endometrial carcinoma. Am J Obstet Gynecol 77:530–538

    PubMed  CAS  Google Scholar 

  16. Cameron RI, Ashe P, O’Rourke DM, Foster H, McCluggage WG (2003) A panel of immunohistochemical stains assists in the distinction between ovarian and renal clear cell carcinoma. Int J Gynecol Pathol 22:272–276

    Article  PubMed  CAS  Google Scholar 

  17. Carlson JW, Nucci MR, Brodsky J, Crum CP, Hirsch MS (2007) Biomarker-assisted diagnosis of ovarian, cervical and pulmonary small cell carcinomas: the role of TTF-1, WT-1 and HPV analysis. Histopathology 51:305–312

    Article  PubMed  CAS  Google Scholar 

  18. Caron P, Roche H, Gorguet B, Martel P, Bennet A, Carton M (1990) Mammary ovarian metastases with stromal cell hyperplasia and postmenopausal virilization. Cancer (Phila) 66:1221–1224

    Article  CAS  Google Scholar 

  19. Che M, Tornos C, Deavers MT (2001) Ovarian mixed-epithelial carcinomas with a microcystic pattern and signet-ring cells. Int J Gynecol Pathol 20:323–328

    Article  PubMed  CAS  Google Scholar 

  20. Chen ZME, Wang HL (2004) Alteration of cytokeratin 7 and cytokeratin 20 expression profile is uniquely associated with tumorigenesis of primary adenocarcinoma of the small intestine. Am J Surg Pathol 28:1352–1359

    Article  PubMed  Google Scholar 

  21. Chu PG, Weiss LM (2004) Immunohistochemical characterization of signet-ring cell carcinomas of the stomach, breast, and colon. Am J Clin Pathol 121:884–892

    Article  PubMed  Google Scholar 

  22. Clement PB, Young RH, Scully RE (1996) Malignant mesotheliomas presenting as ovarian masses. A report of nine cases, including two primary ovarian mesotheliomas. Am J Surg Pathol 20:1067–1080

    Article  PubMed  CAS  Google Scholar 

  23. Creasman WT, Lukeman J (1972) Role of the fallopian tube in dissemination of malignant cells in corpus cancer. Cancer (Phila) 20:456–457

    Article  Google Scholar 

  24. Curtin JP, Barakat RR, Hoskins WJ (1994) Ovarian disease in women with breast cancer. Obstet Gynecol 84:449–452

    PubMed  CAS  Google Scholar 

  25. Daya D, Nazerali L, Frank GL (1992) Metastatic ovarian carcinoma of large intestinal origin simulating primary ovarian carcinoma. A clinicopathologic study of 25 cases. Am J Clin Pathol 97:751–758

    PubMed  CAS  Google Scholar 

  26. DeCostanzo DC, Elias JM, Chumas JC (1997) Necrosis in 84 ovarian carcinomas: a morphologic study of primary versus metastatic colonic cancer with a selective immunohistochemical analysis of cytokeratin subtypes and carcinoembryonic antigen. Int J Gynecol Pathol 16:245–249

    Article  PubMed  CAS  Google Scholar 

  27. Demopoulos RI, Touger L, Dubin N (1987) Secondary ovarian carcinoma: a clinical and pathological evaluation. Int J Gynecol Pathol 6:166–175

    Article  PubMed  CAS  Google Scholar 

  28. Diddle AW (1955) Krukenberg tumors: diagnostic problem. Cancer (Phila) 8:1026–1034

    Article  CAS  Google Scholar 

  29. DiLoreto C, Di Lauro V, Puglisi F et al (1997) Immunocytochemical expression of tissue specific transcription factor-1 in lung carcinoma. J Clin Pathol 50:30–32

    Article  CAS  Google Scholar 

  30. Eichhorn JH, Young RH, Scully RE (1993) Non-pulmonary small cell carcinomas of extragenital origin metastatic to the ovary: a report of seven cases. Cancer (Phila) 71:177–186

    Article  CAS  Google Scholar 

  31. Eifel P, Hendrickson M, Ross J, Ballon S, Martinez A, Kempson R (1982) Simultaneous presentation of carcinoma involving the ovary and the uterine corpus. Cancer (Phila) 50:163–170

    Article  CAS  Google Scholar 

  32. Elhajj M, Mazurka J, Daya D (2002) Desmoplastic small round cell tumor presenting in the ovaries: report of a case and review of the literature. Int J Gynecol Cancer 12:760–763

    Article  PubMed  CAS  Google Scholar 

  33. Elishaev E, Gilks CB, Miller D, Srodon M, Kurman RJ, Ronnett BM (2005) Synchronous and metachronous endocervical and ovarian neoplasms. Evidence supporting interpretation of the ovarian neoplasms as metastatic endocervical adenocarcinomas simulating primary ovarian surface epithelial neoplasms. Am J Surg Pathol 29:281–294

    Article  PubMed  Google Scholar 

  34. Fitzgibbons PL, Martin SE, Simmons TJ (1987) Malignant melanoma metastatic to the ovary. Am J Surg Pathol 11:959–964

    Article  PubMed  CAS  Google Scholar 

  35. Gagnon Y, Tetu B (1989) Ovarian metastases of breast carcinoma. A clinicopathologic study of 59 cases. Cancer (Phila) 64:892–898

    Article  CAS  Google Scholar 

  36. Gokden N, Gokden M, Phan DC, McKenney JK (2008) The utility of PAX-2 in distinguishing metastatic clear cell renal cell carcinoma from its morphologic mimics. An immunohistochemical study with comparison to renal cell carcinoma marker. Am J Surg Pathol 32:1462–1467

    Article  PubMed  Google Scholar 

  37. Goldblum J, Hart WR (1995) Localized and diffuse mesotheliomas of the genital tract and peritoneum in women. A clinicopathological study of nineteen true mesothelial neoplasms, other than adenomatoid tumors, multicystic mesotheliomas and localized fibrous tumors. Am J Surg Pathol 19:1124–1137

    Article  PubMed  CAS  Google Scholar 

  38. Graffner HOL, Alm POA, Oscarson JEA (1983) Prophylactic oophorectomy in colorectal carcinoma. Am J Surg 146:233–235

    Article  PubMed  CAS  Google Scholar 

  39. Green TH Jr, Scully RE (1962) Tumors of the fallopian tube. Clin Obstet Gynecol 5:886–906

    Article  PubMed  Google Scholar 

  40. Green LK, Silva EG (1989) Hepatoblastoma in an adult with metastasis to the ovaries. Am J Clin Pathol 92:110–115

    PubMed  CAS  Google Scholar 

  41. Gupta D, Deavers MT, Silva EG et al (2004) Malignant melanoma involving the ovary. A clinicopathologic and immunohistochemical study of 23 cases. Am J Surg Pathol 28:771–780

    Article  PubMed  Google Scholar 

  42. Hale RW (1968) Krukenberg tumor of the ovaries. A review of 81 records. Obstet Gynecol 32:221–225

    PubMed  CAS  Google Scholar 

  43. Harris M, Howell A, Chrissohou M, Swindell RIC, Hudson M, Sellwood RA (1984) A comparison of the metastatic pattern of infiltrating lobular carcinoma and infiltrating duct carcinoma of the breast. Br J Cancer 50:23–30

    Article  PubMed  CAS  Google Scholar 

  44. Hart WR (2005) Diagnostic challenge of secondary (metastatic) ovarian tumors simulating primary endometrioid and mucinous neoplasms. Pathol Int 55:321–343

    Article  Google Scholar 

  45. Hassan R, Kreitman RJ, Pastan I, Willingham MC (2005) Localization of mesothelin in epithelial ovarian cancer. Mol Morphol 13:243–247

    CAS  Google Scholar 

  46. Hayashi Y, Kikuchi F, Oka T et al (1988) Rhabdomyosarcoma with bone marrow metastasis simulating acute leukemia. Report of two cases. Acta Pathol Jpn 38:789–798

    PubMed  CAS  Google Scholar 

  47. Hecht JL, Pinkus JL, Weinstein LJ et al (2001) The value of thyroid transcription factor-1 in cytologic preparations as a marker for metastatic adenocarcinoma of lung origin. Am J Clin Pathol 116:483–488

    Article  PubMed  CAS  Google Scholar 

  48. Hines JR, Gordon RT, Widger C et al (1976) Cystosarcoma phyllodes metastatic to a Brenner tumor of the ovary. Arch Surg 111:299–300

    Article  PubMed  CAS  Google Scholar 

  49. Holtz F, Hart WR (1982) Krukenberg tumors of the ovary. A clinicopathologic analysis of 27 cases. Cancer (Phila) 50:2438–2447

    Article  CAS  Google Scholar 

  50. Hopping RA, Dockerty MB, Masson JC (1942) Carcinoid tumor of the appendix. Report of a case in which extensive intra-abdominal metastases occurred, including involvement of the right ovary. Arch Surg 45:613–622

    Article  Google Scholar 

  51. Hristov AC, Young RH, Vang R, Yemelyanova AV, Seidman JD, Ronnett BM (2007) Ovarian metastases of appendiceal tumors with goblet cell carcinoid-like and signet ring cell patterns: A report of 30 cases. Am J Surg Pathol 31:1502–1511

    Article  PubMed  Google Scholar 

  52. Hsiu J-G, Kemp GM, Singer GA, Rawls WH, Siddiky MA (1991) Transitional cell carcinoma of the renal pelvis with ovarian metastasis. Gynecol Oncol 41:178–181

    Article  PubMed  CAS  Google Scholar 

  53. Insabato L, DeRosa G, Franco R et al (2003) Ovarian metastasis from renal cell carcinoma: a report of three cases. Int J Surg Pathol 11:309–312

    Article  PubMed  Google Scholar 

  54. Irving JA, Lerwill MF, Young RH (2005) Gastrointestinal stromal tumors metastatic to the ovary. A report of five cases. Am J Surg Pathol 29:920–926

    Article  PubMed  Google Scholar 

  55. Irving JA, Vasques DR, McGuinness TB, Young RH (2006) Krukenberg tumor of renal pelvic origin: report of a case with selected comments on ovarian tumors metastatic from the urinary tract. Int J Gynecol Pathol 25:147–150

    Article  PubMed  Google Scholar 

  56. Irving JA, Young RH (2005) Lung carcinoma metastatic of the ovary. A clinicopathologic study of 32 cases emphasizing their morphologic spectrum and problems in differential diagnosis. Am J Surg Pathol 29:997–1006

    PubMed  Google Scholar 

  57. Ji H, Isacson C, Seidman JD, Kurman RJ, Ronnett BM (2002) Cytokeratins 7 and 20, Dpc4, and MUC5AC in the distinction of metastatic mucinous carcinomas in the ovary from primary ovarian mucinous tumors: Dpc4 assists in identifying metastatic pancreatic carcinomas. Int J Gynecol Pathol 21:391–400

    Article  PubMed  Google Scholar 

  58. Judson K, McCormick C, Vang R, Yemelyanova AV, Wu LSF, Bristow RE, Ronnett BM (2008) Women with undiagnosed colorectal adenocarcinomas presenting with ovarian metastases: Clinicopathologic features and comparison with women having known colorectal adenocarcinomas and ovarian involvement. Int J Gynecol Pathol 27:182–190

    PubMed  Google Scholar 

  59. Kaminski PF, Norris HJ (1984) Coexistence of ovarian neoplasms and endocervical adenocarcinoma. Obstet Gynecol 64:553–556

    PubMed  CAS  Google Scholar 

  60. Kanner WA, Galgano MT, Stoler MH, Mills SE, Atkins KA (2008) Distinguishing breast carcinoma from mullerian serous carcinoma with mammaglobin and mesothelin. Int J Gynecol Pathol 27:491–495

    Article  PubMed  Google Scholar 

  61. Karsh J (1951) Secondary malignant disease of the ovaries. A study of 72 autopsies. Am J Obstet Gynecol 61:154–160

    PubMed  CAS  Google Scholar 

  62. Kaufmann O, Dietel M (2000) Thyroid transcription factor-1 is the superior immunohistochemical marker for pulmonary adenocarcinomas and large cell carcinomas compared to surfactant proteins A and B. Histopathology 36:8–16

    Article  PubMed  CAS  Google Scholar 

  63. Khunamornpong S, Lerwill MF, Siriaunkgul S, Suprasert P, Pojchamarnwiputh S, Chiangmai WN, Young RH (2008) Carcinoma of extrahepatic bile ducts and gallbladder metastatic to the ovary: a report of 16 cases. Int J Gynecol Pathol 27:366–379

    Article  PubMed  Google Scholar 

  64. Khunamornpong S, Siriaunkgul S, Chunduan A (1999) Metastatic hepatocellular carcinoma of the ovary. Int J Gynecol Obstet 64:189–191

    Article  CAS  Google Scholar 

  65. Khunamornpong S, Siriaunkgul S, Suprasert P, Pojchamarnwiputh S, Chiangmai WN, Young RH (2007) Intrahepatic cholangiocarcinoma metastatic to the ovary: A report of 16 cases of an underemphasized form of secondary tumor of the ovary that may mimic primary neoplasia. Am J Surg Pathol 31:1788–1799

    Article  PubMed  Google Scholar 

  66. Khunamornpong S, Suprasert P, Chiangmai WN, Siriaunkgul S (2006) Metastatic tumors to the ovaries: a study of 170 cases in Northern Thailand. Int J Gynecol Cancer 16:132–138

    Article  PubMed  Google Scholar 

  67. Khunamornpong S, Suprasert PS, Pojchamarnwiputh S, Chiangmai WN, Settakorn J, Siriaunkgul S (2006) Primary and metastatic mucinous adenocarcinomas of the ovary: evaluation of the diagnostic approach using tumor size and laterality. Gynecol Oncol 101:152–157

    Article  PubMed  Google Scholar 

  68. Kim KR, Lee HI, Lee SK, Ro JY, Robboy SJ (2007) Is stromal microinvasion in primary mucinous ovarian tumors with “mucin granuloma” true invasion? Am J Surg Pathol 31:546–554

    Article  PubMed  Google Scholar 

  69. Kim K-R, Scully RE (1990) Peritoneal keratin granulomas with carcinomas of endometrium and ovary and atypical polypoid adenomyoma of endometrium. A clinicopathological analysis of 22 cases. Am J Surg Pathol 14:925–932

    Article  PubMed  CAS  Google Scholar 

  70. Kindelberger DW, Lee Y, Miron A, Hirsch MS, Feltmate C, Medeiros F, Callahan MJ, Garner EO, Gordon RW, Birch C, Berkowitz RS, Muto MG, Crum CP (2007) Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: evidence for a causal relationship. Am J Surg Pathol 31:161–169

    Article  PubMed  Google Scholar 

  71. Kiyokawa T, Young RH, Scully RE (2006) Krukenberg tumors of the ovary. A clinicopathologic analysis of 120 cases with emphasis on their variable pathologic manifestations. Am J Surg Pathol 31:277–299

    Google Scholar 

  72. Kubba LA, McCluggage WG, Liu J, Malpica A, Euscher ED, Silva EG, Deavers MT (2008) Thyroid transcription factor-1 expression in ovarian epithelial neoplasms. Mod Pathol 21:485–490

    Article  PubMed  CAS  Google Scholar 

  73. Kuo T-T, Hsueh S (1984) Mucicarminophilic histiocytosis. A polyvinylpyrrolidone (PVP) storage disease simulating signet-ring cell carcinoma. Am J Surg Pathol 8:419–428

    Article  PubMed  CAS  Google Scholar 

  74. Kurek R, Von Knoblock R, Feek U, Heidenreich A, Hofmann R (2001) Local recurrence of an oncocytic adrenocortical carcinoma with ovary metastasis. J Urol 166:985

    Article  PubMed  CAS  Google Scholar 

  75. Lash RH, Hart WR (1987) Intestinal adenocarcinomas metastatic to the ovaries. A clinicopathological evaluation of 22 cases. Am J Surg Pathol 11:114–121

    Article  PubMed  CAS  Google Scholar 

  76. Lee MJ, Lee HS, Kim WH, Choi Y, Yang M (2003) Expressions of mucins and cytokeratins in primary carcinomas of the digestive system. Mod Pathol 16:403–410

    Article  PubMed  Google Scholar 

  77. Lee AHS, Paish EC, Marchio C, Sapino A, Schmitt FC, Ellis IO, Reis-Filho JS (2007) The expression of Wilms’ tumour-1 and Ca125 in invasive micropapillary carcinoma of the breast. Histopathology 51:824–828

    Article  PubMed  CAS  Google Scholar 

  78. Lee KR, Young RH (2003) The distinction between primary and metastatic mucinous carcinomas of the ovary. Am J Surg Pathol 2:281–292

    Article  Google Scholar 

  79. Leroy X, Farine MO, Buob D, Wacrenier A, Copin MC (2007) Diagnostic value of cytokeratin 7, CD10 and mesothelin in distinguishing ovarian clear cell carcinoma from metastasis of renal clear cell carcinoma. Histopathology 51:846–876

    Article  Google Scholar 

  80. Lerwill MF (2004) Current practical applications of diagnostic immunohistochemistry in breast pathology. Am J Surg Pathol 28:1076–1091

    Article  PubMed  Google Scholar 

  81. Lerwill MF, Young RH (2006) Ovarian metastases of intestinal-type gastric carcinoma. A clinicopathologic study of 4 cases with contrasting features to those of the Krukenberg tumor. Am J Surg Pathol 31:1382–1388

    Article  Google Scholar 

  82. Lewis MR, Deavers MT, Silva EG, Malpica A (2006) Ovarian involvement by metastatic colorectal adenocarcinoma. Still a diagnostic challenge. Am J Surg Pathol 30:177–184

    Article  PubMed  Google Scholar 

  83. LiVolsi VA, Merino MJ, Schwartz PE (1983) Coexistent endocervical adenocarcinoma and mucinous adenocarcinoma of ovary: a clinicopathological study of four cases. Int J Gynecol Pathol 1:391–402

    Article  PubMed  CAS  Google Scholar 

  84. Logani S, Baloch ZW, Snyder PJ, Weinstein R, LiVolvi VA (2001) Cystic ovarian metastasis from papillary thyroid carcinoma: a case report. Thyroid 11:1073–1075

    Article  PubMed  CAS  Google Scholar 

  85. Logani S, Oliva E, Amin MB, Folpe AL, Cohen C, Young RH (2003) Immunoprofile of ovarian tumors with putative transitional cell (urothelial) differentiation using novel urothelial markers. Histogenic and diagnostic implications. Am J Surg Pathol 27:1434–1441

    Article  PubMed  Google Scholar 

  86. Logani S, Oliva E, Arnell PM, Amin MB, Young RH (2005) Use of novel immunohistochemical markers expressed in colonic adenocarcinoma to distinguish primary ovarian tumors from metastatic colorectal carcinoma. Mod Pathol 18:19–25

    Article  PubMed  CAS  Google Scholar 

  87. Longacre TA, O’Hanlan K, Hendrickson MR (1996) Adenoid cystic carcinoma of the submandibular gland with symptomatic ovarian metastases. Int J Gynecol Pathol 15:349–355

    Article  PubMed  CAS  Google Scholar 

  88. Lumb G, Mackenzie DH (1959) The incidence of metastases in adrenal glands and ovaries removed for carcinoma of the breast. Cancer (Phila) 12:521–526

    Article  CAS  Google Scholar 

  89. MacKeigan JM, Ferguson JA (1979) Prophylactic oophorectomy and colorectal cancer in premenopausal patients. Dis Colon Rectum 22:401–405

    Article  PubMed  CAS  Google Scholar 

  90. Mazur MT, Hsueh S, Gersell DJ (1984) Metastases to the female genital tract. Analysis of 325 cases. Cancer (Phila) 53:1978–1984

    Article  CAS  Google Scholar 

  91. McCluggage WG (2008) Immunohistochemical markers as a diagnostic aid in ovarian pathology. Diagn Histopathol 14:335–351

    Article  Google Scholar 

  92. McCluggage WG, Bissonnette JP, Young RH (2006) Primary malignant melanoma of the ovary: A report of 9 definite or probable cases with emphasis on their morphologic diversity and mimicry of other primary and secondary ovarian neoplasms. Int J Gynecol Pathol 25:321–329

    Article  PubMed  Google Scholar 

  93. McCluggage WG, Wilkinson N (2005) Metastatic neoplasms involving the ovary: a review with an emphasis on morphological and immunohistochemical features. Histopathology 47:231–247

    Article  PubMed  CAS  Google Scholar 

  94. McCluggage WG, Young RH (2005) Immunohistochemistry as a diagnostic aid in the evaluation of ovarian tumors. Semin Diagn Pathol 22:3–32

    Article  PubMed  Google Scholar 

  95. McCluggage WG, Young RH (2008) Primary ovarian mucinous tumors with signet ring cells: report of three cases with discussion of so-called primary Krukenberg tumor. Am J Surg Pathol 32:1373–1379

    Article  PubMed  Google Scholar 

  96. McKenney JK, Soslow RA, Longacre TA (2008) Ovarian mature teratomas with mucinous epithelial neoplasms: Morphologic heterogeneity and association with pseudomyxoma peritonei. Am J Surg Pathol 32:645–655

    Article  PubMed  Google Scholar 

  97. Merino MJ, Edmonds P, LiVolsi V (1985) Appendiceal carcinoma metastatic to the ovaries and mimicking primary ovarian tumors. Int J Gynecol Pathol 4:110–120

    Article  PubMed  CAS  Google Scholar 

  98. Meyer WH, Yu GW, Milvenan ES, Jeffs RD, Kaizer H, Leventhal BG (1979) Ovarian involvement in neuroblastoma. Med Pediatr Oncol 7:49–54

    Article  PubMed  CAS  Google Scholar 

  99. Milingos D, Doumplis D, Savage P, Seckl M, Lindsay I, Smith JR (2007) Placental site trophoblastic tumor with an ovarian metastasis. Int J Gynecol Cancer 17:925–927

    Article  PubMed  CAS  Google Scholar 

  100. Misdraji J, Yantiss RK, Graeme-Cook FM, Balis UJ, Young RH (2003) Appendiceal mucinous neoplasms. A clinicopathologic analysis of 107 cases. Am J Surg Pathol 27:1089–1103

    Article  PubMed  Google Scholar 

  101. Monteagudo C, Merino MJ, Laporte N, Neumann RD (1991) Value of gross cystic disease fluid protein-15 in distinguishing metastatic breast carcinomas among poorly differentiated neoplasms involving the ovary. Hum Pathol 22:368–372

    Article  PubMed  CAS  Google Scholar 

  102. Moritani S, Ichihara S, Hasegawa M, Endo T, Oiwa M, Yoshikawa K, Sato Y, Aoyama H, Hayashi T, Kushima R (2008) Serous papillary adenocarcinoma of the female genital organs and invasive micropapillary carcinoma of the breast. Are WT1, CA125, and GCDFP-15 useful in differential diagnosis? Hum Pathol 39:666–671

    Article  PubMed  CAS  Google Scholar 

  103. Nguyen L, Brewer CA, DiSaia PJ (1998) Ovarian metastasis of Stage 1B1 squamous cell cancer of the cervix after radical parametrectomy and oophoropexy. Gynecol Oncol 68:198–200

    Article  PubMed  CAS  Google Scholar 

  104. Nonaka D, Chiriboga L, Soslow RA (2008) Expression of Pax8 as a useful marker in distinguishing ovarian carcinomas from mammary carcinomas. Am J Surg Pathol 32:1566–1571

    Article  PubMed  Google Scholar 

  105. Oberg KC, Wells K, Seraj IM et al (2002) ACTH-secreting islet cell tumor of the pancreas presenting as bilateral ovarian tumors and Cushing’s syndrome. Int J Gynecol Pathol 21:276–280

    Article  PubMed  Google Scholar 

  106. Ohira S, Shiohara S, Itoh K et al (2003) Urachal adenocarcinoma metastatic to the ovaries: case report and literature review. Int J Gynecol Pathol 22:189–193

    Article  PubMed  Google Scholar 

  107. Ohta Y, Suzuki T, Shiokawa A, Mitsuya T, Ota H (2005) Expression of CD10 and cytokeratins in ovarian and renal clear cell carcinoma. Int J Gynecol Pathol 24:239–245

    Article  PubMed  Google Scholar 

  108. Oliva E, Musulen E, Prat J, Young RH (1993) Transitional cell carcinoma of the renal pelvis with symptomatic ovarian metastases. Int J Surg Pathol 2:231–236

    Article  Google Scholar 

  109. Onuma K, Dabbs DJ, Bhargava R (2008) Mammaglobin expression in the female genital tract: immunohistochemical analysis in benign and neoplastic endocervix and endometrium. Int J Gynecol Pathol 27:418–425

    Article  PubMed  Google Scholar 

  110. Parker LP, Duong JL, Wharton JT, Malpica A, Silva EG, Deavers MT (2002) Desmoplastic small round cell tumor: report of a case presenting as a primary ovarian neoplasm. Eur J Gynaec Oncol 23:199–202

    CAS  Google Scholar 

  111. Petru E, Pickel H, Heydarfadai M, Lahousen M, Haas J, Schaider H, Tamussino K (1992) Nongenital cancers metastatic to the ovary. Gynecol Oncol 44:83–86

    Article  PubMed  CAS  Google Scholar 

  112. Phillips V, McCluggage WG, Young RH (2006) Oxyphilic adenomatoid tumor of the ovary: a case report with discussion of the differential diagnosis of ovarian tumors with vacuoles and related spaces. Int J Gynecol Pathol 26:16–20

    Article  Google Scholar 

  113. Pins MR, Young RH, Crum CP, Leach IH, Scully RE (1997) Cervical squamous carcinoma in situ with superficial extension to corpus and tubes and invasion of tubes and ovaries. Int J Gynecol Pathol 16:272–278

    Article  PubMed  CAS  Google Scholar 

  114. Pitluk H, Poticha SM (1983) Carcinoma of the colon and rectum in patients less than 40 years of age. Surg Gynecol Obstet 157:335–337

    PubMed  CAS  Google Scholar 

  115. Pitman MB, Triratanachat S, Young RH, Oliva E (2003) Hepatocyte paraffin 1 antibody does not distinguish primary ovarian tumors with hepatoid differentiation from metastatic hepatocellular carcinoma. Int J Gynecol Pathol 23:58–64

    Google Scholar 

  116. Prayson RA, Hart WR, Petras RE (1994) Pseudo-myxoma peritonei. A clinicopathologic study of 19 cases with emphasis on site of origin and nature of associated ovarian tumors. Am J Surg Pathol 18:591–603

    PubMed  CAS  Google Scholar 

  117. Rabban JT, Lerwill MF, McCluggage WG, Grenert JP, Zaloudek CJ (2009) Primary ovarian carcinoid tumors may express CDX-2: a potential pitfall in distinction from metastatic intestinal carcinoid tumors involving the ovary. Int J Gynecol Pathol 28:41–48

    Article  PubMed  Google Scholar 

  118. Reis-Filho JS, Carrilho C, Valenti C et al (2000) Is TTF1 a good immunohistochemical marker to distinguish primary from metastatic lung adenocarcinomas? Pathol Res Pract 196:835–840

    Article  PubMed  CAS  Google Scholar 

  119. Riopel MA, Ronnett BM, Kurman RJ (1999) Evaluation of diagnostic criteria and behavior of ovarian intestinal-type mucinous tumors. Atypical proliferative (borderline) tumors and intraepithelial, microinvasive, invasive, and metastatic carcinomas. Am J Surg Pathol 23:617–635

    Article  PubMed  CAS  Google Scholar 

  120. Robboy SJ, Scully RE, Norris HJ (1974) Carcinoid metastatic to the ovary. A clinicopathologic analysis of 35 cases. Cancer (Phila) 33:798–811

    Article  CAS  Google Scholar 

  121. Ronnett BM, Kurman RJ, Shmookler BM, Sugarbaker PH, Young RH (1997) The morphologic spectrum of ovarian metastases of appendical adenocarcinomas. A clinicopathologic and immunohistochemical analysis of tumors often misinterpreted as primary ovarian tumors or metastatic tumors from other gastrointestinal sites. Am J Surg Pathol 2:1144–1155

    Article  Google Scholar 

  122. Ronnett BM, Kurman RJ, Zahn CM, Shmookler BM, Jablonski KA, Kass ME (1995) Pseudomyxoma peritonei in women. A clinicopathologic analysis of 30 cases with emphasis on site of origin, prognosis, and relationship to ovarian mucinous tumors of low malignant potential. Hum Pathol 26:509–524

    Article  PubMed  CAS  Google Scholar 

  123. Ronnett BM, Shmookler BM, Diener-West M, Sugarbaker PH, Kurman RJ (1997) Immunohistochemical evidence supporting the appendiceal origin of pseudomyxoma peritonei in women. Int J Gynecol Pathol 16:1–9

    Article  PubMed  CAS  Google Scholar 

  124. Ronnett BM, Yemelyanova AV, Vang R, Gilks CB, Miller D, Gravitt PE, Kurman RJ (2008) Endocervical adenocarcinomas with ovarian metastases. Analysis of 29 cases with emphasis on minimally invasive cervical tumors and the ability of the metastases to simulate primary ovarian neoplasms. Am J Surg Pathol 32:1835–1853

    Article  PubMed  Google Scholar 

  125. Ronnett BM, Zahn CM, Kurman RJ, Kass ME, Sugarbaker PH, Shmookler BM (1995) Disseminated peritoneal adenomucinosis and peritoneal mucinous carcinomatosis: a clinicopathologic analysis of 109 cases with emphasis on distinguishing pathologic features, site of origin, prognosis, and relationship to “pseudomyxoma peritonei”. Am J Surg Pathol 19:1390–1408

    Article  PubMed  CAS  Google Scholar 

  126. Saphir O (1951) Signet-ring cell carcinoma. Mil Surg 109:360–369

    PubMed  CAS  Google Scholar 

  127. Sasaki E, Tsunoda N, Hatanaka Y, Mori N, Iwata H, Yatabe Y (2007) Breast-specific expression of MGB1/mammaglobin: an examination of 480 tumors from various organs and clinicopathological analysis of MGB1-positive breast cancers. Mod Pathol 20:208–214

    Article  PubMed  CAS  Google Scholar 

  128. Scully RE, Richardson GS (1961) Luteinization of the stroma of metastatic cancer involving the ovary and its endocrine significance. Cancer (Phila) 14:827–840

    Article  CAS  Google Scholar 

  129. Seidman JD, Elsayed AM, Sobin LH, Tavassoli FA (1993) Association of mucinous tumors of the ovary and appendix. A clinicopathologic study of 25 cases. Am J Surg Pathol 17:22–34

    Article  PubMed  CAS  Google Scholar 

  130. Seidman JD, Kurman RJ, Ronnett BM (2003) Incidence in routine practice with a new approach to improve intraoperative diagnosis. Primary and metastatic mucinous adenocarcinomas in the ovaries. Am J Surg Pathol 27:985–993

    Article  PubMed  Google Scholar 

  131. Smale L (1980) Metastatic breast adenocarcinoma to Brenner tumors. Gynecol Oncol 9:251–253

    Article  PubMed  CAS  Google Scholar 

  132. Soslow RA, Rouse RV, Hendrickson MR, Silva EG, Longacre TA (1996) Transitional cell neoplasms of the ovary and urinary bladder: a comparative immunohistochemical analysis. Int J Gynecol Pathol 15:257–265

    Article  PubMed  CAS  Google Scholar 

  133. Spencer JR, Eriksen B, Garnett JE (1993) Metastatic renal tumor presenting as ovarian clear cell carcinoma. Urology 41:582–584

    Article  PubMed  CAS  Google Scholar 

  134. Stewart CJR, Brennan BA, Hammond IG et al (2005) Accuracy of frozen section in distinguishing primary ovarian neoplasia from tumors metastatic to the ovary. Int J Gynecol Pathol 24:356–362

    Article  PubMed  Google Scholar 

  135. Strosberg J, Nasir A, Cragun J, Gardner N, Kvols L (2007) Metastatic carcinoid tumor to the ovary: a clinicopathologic analysis of seventeen cases. Gynecol Oncol 106:65–68

    Article  PubMed  Google Scholar 

  136. Sty JR, Kun LE, Casper JT (1980) Bone scintigraphy in neuroblastoma with ovarian metastasis. Wis Med J 79:28–29

    Google Scholar 

  137. Szych C, Staebler A, Connolly DC, Wu R, Cho KR, Ronnett BM (1999) Molecular genetic evidence supporting the clonality and appendiceal origin of pseudomyxoma peritonei in women. Am J Pathol 154:1849–1855

    Article  PubMed  CAS  Google Scholar 

  138. Tabata M, Ichinoe K, Sakuragi N, Shina Y, Yamaguchi T, Mabuchi Y (1987) Incidence of ovarian metastasis in patients with cancer of the uterine cervix. Gynecol Oncol 28:255–261

    Article  PubMed  CAS  Google Scholar 

  139. Tang LH, Shia J, Soslow RA, Dhall D, Wong WD, O’Reilly E, Qin J, Paty P, Weiser MR, Guillem J, Temple L, Sobin LH, Klimstra DS (2008) Pathologic classification and clinical behavior of the spectrum of goblet cell carcinoid tumors of the appendix. Am J Surg Pathol 32:1429–1443

    Article  PubMed  Google Scholar 

  140. Toki N, Tsukamoto N, Kaku T et al (1991) Microscopic ovarian metastasis of the uterine cervical cancer. Gynecol Oncol 41:46–51

    Article  PubMed  CAS  Google Scholar 

  141. Tornos C, Soslow R, Chen S et al (2005) Expression of WT1, CA 125, and GCDFP-15 as useful markers in the differential diagnosis of primary ovarian carcinomas versus metastatic breast cancer to the ovary. Am J Surg Pathol 29:1482–1489

    Article  PubMed  Google Scholar 

  142. Tso PL, Bringaze WL III, Dauterive AH, Correa P, Cohn I Jr (1987) Gastric carcinoma in the young. Cancer (Phila) 59:1362–1365

    Article  CAS  Google Scholar 

  143. Ulbright TM, Roth LM (1985) Metastatic and independent cancers of the endometrium and ovary: a clinicopathologic study of 34 cases. Hum Pathol 16:28–34

    Article  PubMed  CAS  Google Scholar 

  144. Ulbright TM, Roth LM (1985) Secondary tumors of the ovary. In: Roth LM, Czernobilsky B (eds) Tumors and tumor-like conditions of the ovary, vol 6, Contemporary issues in surgical pathology. Churchill-Livingstone, New York, pp 129–152

    Google Scholar 

  145. Ulbright TM, Roth LM, Stehman FB (1984) Secondary ovarian neoplasia. A clinicopathologic study of 35 cases. Cancer (Phila) 53:1164–1174

    Article  CAS  Google Scholar 

  146. Vakiani E, Young RH, Carcangiu ML, Klimstra DS (2008) Acinar cell carcinoma of the pancreas metastatic to the ovary. A report of 4 cases. Am J Surg Pathol 32:1540–1545

    Article  PubMed  Google Scholar 

  147. Vang R, Gown AM, Barry TS, Wheeler DT, Yemelyanova A, Seidman JD, Ronnett BM (2006) Cytokeratins 7 and 20 in primary and secondary mucinous tumors of the ovary: analysis of coordinate immunohistochemical expression profiles and staining distribution in 179 cases. Am J Surg Pathol 30:1130–1139

    Article  PubMed  Google Scholar 

  148. Vang R, Gown AM, Wu LSF, Barry TS, Wheeler DT, Yemelyanova A, Seidman JD, Ronnett BM (2006) Immunohistochemical expression of CDX2 in primary ovarian mucinous tumors and metastatic mucinous carcinomas involving the ovary: comparison with CK20 and correlation with coordinate expression of CK7. Mod Pathol 19:1421–1428

    Article  PubMed  CAS  Google Scholar 

  149. Vang R, Gown AM, Zhao C, Barry TS, Isacson C, Richardson MS, Ronnett BM (2007) Ovarian mucinous tumors associated with mature cystic teratomas. Morphologic and immunohistochemical analysis identifies a subset of potential teratomatous origin that shares features of lower gastrointestinal tract mucinous tumors more commonly encountered as secondary tumors in the ovary. Am J Surg Pathol 31:854–869

    Article  PubMed  Google Scholar 

  150. Vara A, Madrigal B, Veiga M, Diaz A, Garcia J, Calvo J (1998) Bilateral ovarian metastases from renal clear cell carcinoma. Acta Oncol (Stockh) 37:379–380

    Article  CAS  Google Scholar 

  151. Veras E, Srodon M, Neijstrom ES, Ronnett BM (2009) Metastatic HPV-related cervical adenocarcinomas presenting with thromboembolic events (Trousseau syndrome): clinicopathologic characteristics of two cases. Int J Gynecol Pathol 28:134–139

    Article  PubMed  Google Scholar 

  152. Webb MJ, Decker DG, Mussey E (1975) Factors influencing survival. Cancer metastatic to the ovary. Obstet Gynecol 45:391–396

    PubMed  CAS  Google Scholar 

  153. Wheelock MC, Putong P (1959) Ovarian metastases from adenocarcinomas of colon and rectum. Obstet Gynecol 14:291–295

    PubMed  CAS  Google Scholar 

  154. Wick MR, Lillemoe TJ, Copland GT, Swanson PE, Manivel JC, Kiang DT (1989) Gross cystic disease fluid protein-15 as a marker for breast cancer: immunohistochemical analysis of 690 human neoplasms and comparison with alpha-lactalbumin. Hum Pathol 20:281–287

    Article  PubMed  CAS  Google Scholar 

  155. Woodruff JD, Murthy YS, Bhaskar TN, Bordbar F, Tseng S-S (1970) Metastatic ovarian tumors. Am J Obstet Gynecol 107:202–209

    PubMed  CAS  Google Scholar 

  156. Yakushiji M, Tazaki T, Nishimura H, Kato T (1987) Krukenberg tumors of the ovary: a clinicopathologic analysis of 112 cases. Acta Obstet Gynaecol Jpn 39:479–485

    CAS  Google Scholar 

  157. Yemelyanova AV, Vang R, Judson K, Wu LSF, Ronnett BM (2008) Distinction of primary and metastatic mucinous tumors involving the ovary: analysis of size and laterality data by primary site with reevaluation of an algorithm for tumor classification. Am J Surg Pathol 32:128–138

    Article  PubMed  Google Scholar 

  158. Yoshida A, Shigematsu T, Mori H, Yoshida H, Fukunishi R (1981) Non-invasive thymoma with widespread blood-borne metastasis. Virchows Arch (Path Anat) 390:121–126

    Article  CAS  Google Scholar 

  159. Young RH (1995) Urachal adenocarcinoma metastatic to the ovary simulating primary mucinous cystadenocarcinoma of the ovary: report of a case. Virchows Arch 426:529–532

    Article  PubMed  CAS  Google Scholar 

  160. Young RH (2004) Pseudomyxoma peritonei and selected other aspects of the spread of appendiceal neoplasms. Semin Diagn Pathol 21:134–150

    Article  PubMed  Google Scholar 

  161. Young RH (2006) From Krukenberg to today: The ever present problems posed by metastatic tumors in the ovary. Part I. Historical perspective, general principles, mucinous tumors including the Krukenberg tumor. Adv Anat Pathol 13:205–227

    Article  PubMed  Google Scholar 

  162. Young RH (2007) From Krukenberg to today: the ever present problems posed by metastatic tumors in the ovary. Part II. Adv Anat Pathol 14:149–177

    Article  PubMed  Google Scholar 

  163. Young RH, Carey RW, Robboy SJ (1981) Breast carcinoma masquerading as a primary ovarian neoplasm. Cancer (Phila) 48:210–212

    Article  CAS  Google Scholar 

  164. Young RH, Eichhorn JH, Dickersin GR, Scully RE (1992) Ovarian involvement by the intra-abdominal desmoplastic small round cell tumor with divergent differentiation. A report of three cases. Hum Pathol 23:454–464

    Article  PubMed  CAS  Google Scholar 

  165. Young RH, Gersell DJ, Clement PB, Scully RE (1992) Hepatocellular carcinoma metastatic to the ovary: a report of three cases discovered during life with discussion of the differential diagnosis of hepatoid tumors of the ovary. Hum Pathol 23:574–580

    Article  PubMed  CAS  Google Scholar 

  166. Young RH, Gersell DJ, Roth LM, Scully RE (1993) Ovarian metastases from cervical carcinomas other than pure adenocarcinomas: a report of 12 cases. Cancer (Phila) 71:407–418

    Article  CAS  Google Scholar 

  167. Young RH, Gilks CB, Scully RE (1991) Mucinous tumors of the appendix associated with mucinous tumors of the ovary and pseudomyxoma peritonei: a clinicopathological analysis of 22 cases supporting an origin in the appendix. Am J Surg Pathol 15:415–429

    Article  PubMed  CAS  Google Scholar 

  168. Young RH, Hart WR (1989) Metastases from carcinomas of the pancreas simulating primary mucinous tumors of the ovary: a report of seven cases. Am J Surg Pathol 13:748–756

    Article  PubMed  CAS  Google Scholar 

  169. Young RH, Hart WR (1992) Renal cell carcinoma metastatic to the ovary: a report of three cases emphasizing possible confusion with ovarian clear cell adenocarcinoma. Int J Gynecol Pathol 11:96–104

    Article  PubMed  CAS  Google Scholar 

  170. Young RH, Hart WR (1998) Metastatic intestinal carcinomas simulating primary ovarian clear cell carcinoma and secretory endometrioid carcinoma. A clinicopathologic and immunohistochemical study of five cases. Am J Surg Pathol 22:805–815

    Article  PubMed  CAS  Google Scholar 

  171. Young RH, Jackson A, Wells M (1994) Ovarian metastasis from thyroid carcinoma twelve years after partial thyroidectomy mimicking struma ovarii. Report of a case. Int J Gynecol Pathol 13:181–185

    Article  PubMed  CAS  Google Scholar 

  172. Young RH, Kozakewich HPW, Scully RE (1993) Metastatic ovarian tumors in children: a report of 14 cases and review of the literature. Int J Gynecol Pathol 12:8–19

    Article  PubMed  CAS  Google Scholar 

  173. Young RH, Prat J, Scully RE (1984) Endometrial stromal sarcomas of the ovary. A clinicopathologic analysis of 23 cases. Cancer (Phila) 53:1143–1155

    Article  CAS  Google Scholar 

  174. Young RH, Scully RE (1985) Ovarian metastases from cancer of the lung: problems in interpretation – a report of seven cases. Gynecol Oncol 21:337–350

    Article  PubMed  CAS  Google Scholar 

  175. Young RH, Scully RE (1988) Mucinous tumors of the ovary associated with mucinous adenocarcinomas of the cervix. A clinicopathological analysis of 16 cases. Int J Gynecol Pathol 7:99–111

    Article  PubMed  CAS  Google Scholar 

  176. Young RH, Scully RE (1988) Urothelial and ovarian carcinomas of identical cell types: problems in interpretation. A report of three cases and review of the literature. Int J Gynecol Pathol 7:197–211

    Article  PubMed  CAS  Google Scholar 

  177. Young RH, Scully RE (1989) Alveolar rhabdomyosarcoma metastatic to the ovary. A report of two cases and discussion of the differential diagnosis of small cell malignant tumors of the ovary. Cancer (Phila) 64:899–904

    Article  CAS  Google Scholar 

  178. Young RH, Scully RE (1990) Ovarian metastases from carcinoma of the gallbladder and extrahepatic bile ducts simulating primary tumors of the ovary: a report of six cases. Int J Gynecol Pathol 9:60–72

    Article  PubMed  CAS  Google Scholar 

  179. Young RH, Scully RE (1990) Sarcomas metastatic to the ovary. A report of 21 cases. Int J Gynecol Pathol 9:231–252

    Article  PubMed  CAS  Google Scholar 

  180. Young RH, Scully RE (1991) Malignant melanoma metastatic to the ovary: a clinicopathologic analysis of 20 cases. Am J Surg Pathol 15:849–860

    Article  PubMed  CAS  Google Scholar 

  181. Young RH, Scully RE (1991) Metastatic tumors in the ovary: a problem-oriented approach and review of the recent literature. Semin Diagn Pathol 8:250–276

    PubMed  CAS  Google Scholar 

  182. Young RH, Scully RE (2001) Differential diagnosis of ovarian tumors based primarily on their patterns and cell types. Semin Diagn Pathol 18:161–235

    PubMed  CAS  Google Scholar 

  183. Yu TJ, Iwasaki I, Horie H, Tamaru J, Takahashi A (1986) Endolymphatic stromal myosis of the uterus with metastasis to ovary and recurrence in vagina. Acta Pathol Jpn 36:301–308

    PubMed  CAS  Google Scholar 

  184. Zaino RJ, Unger ER, Whitney C (1984) Synchronous carcinomas of the uterine corpus and ovary. Gynecol Oncol 19:329–335

    Article  PubMed  CAS  Google Scholar 

  185. Zaloudek C, Miller TR, Stern JL (1995) Desmoplastic small cell tumor of the ovary: a unique polyphenotypic tumor with an unfavorable prognosis. Int J Gynecol Oncol 14:260–265

    CAS  Google Scholar 

  186. Zamecnik M, Voltr L, Stuk J, Chlumska A (2008) Krukenberg tumor with yolk sac tumor differentiation. Int J Gynecol Pathol 27:223–228

    PubMed  Google Scholar 

  187. Zhang PJ, Gao HG, Pasha TL, Litzky L, LiVolsi V (2009) TTF-1 expression in ovarian and uterine epithelial neoplasia and its potential significance, an immunohistochemical assessment with multiple monoclonal antibodies and different secondary detection systems. Int J Gynecol Pathol 28:10–18

    Article  PubMed  Google Scholar 

  188. Zukerberg LR, Young RH (1990) Chordoma metastatic to the ovary: report of a case. Arch Path Lab Med 114:208–210

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Pathology, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA, 02114, USA

    Melinda F. Lerwill

  2. Anatomic Pathology, James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Warren Bldg. 2nd Floor, Boston, MA, 02114, USA

    Robert H. Young

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  1. Melinda F. Lerwill
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Correspondence to Melinda F. Lerwill .

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Editors and Affiliations

  1. Departments of Gynecology, Obstetrics, Pathology and Oncology, The Johns Hopkins University School of Medicine and Director of Gynecologic Pathology, The Johns Hopkins Hospital, 401 N. Broadway, Weinberg Building Room 2242, Baltimore, MD, 21231, USA

    Robert J. Kurman (Richard W. TeLinde Distinguished Professor of Gynecologic Pathology) (Richard W. TeLinde Distinguished Professor of Gynecologic Pathology)

  2. Department of Pathology and Laboratory Medicine, Weill Cornell Medical College and New York Presbyterian Hospital, 525 East 68th Street, Starr 1015, New York, NY, 10065, USA

    Lora Hedrick Ellenson

  3. Department of Pathology, Johns Hopkins University School of Medicine, 401 N. Broadway, Weinberg Building 2242, Baltimore, MD, 21231, USA

    Brigitte M. Ronnett

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Lerwill, M.F., Young, R.H. (2011). Metastatic Tumors of the Ovary. In: Kurman, R.J., Ellenson, L.H., Ronnett, B.M. (eds) Blaustein’s Pathology of the Female Genital Tract. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-0489-8_18

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