Encyclopedia of Signaling Molecules

2012 Edition
| Editors: Sangdun Choi

Toll-like Receptor Adaptor Protein Family Members

  • Enda Shevlin
  • Sinéad M. Miggin
Reference work entry
DOI: https://doi.org/10.1007/978-1-4419-0461-4_608

Synonyms

Historical Background

Toll-like receptors (TLRs) play a critical role in innate immunity by providing a frontline defense mechanism against invading pathogens such as bacteria, fungi and viruses. They accomplish this by recognising evolutionarily conserved pathogen-associated molecular patterns (PAMPs) which...

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References

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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Department of BiologyInstitute of Immunology, National University of Ireland MaynoothMaynooth, Co. KildareIreland