Encyclopedia of Signaling Molecules

2012 Edition
| Editors: Sangdun Choi

Tead

Reference work entry
DOI: https://doi.org/10.1007/978-1-4419-0461-4_357

Synonyms

Historical Background

In vertebrates, the TEAD family of transcription factors is comprised of four members that contain a highly conserved (99–100%) DNA-binding domain, designated the TEA/ATTS domain (Burglin 1991) (Fig.  1). This highly conserved domain is comprised of three α helical domains and is not confined to vertebrates, but is also found in transcription factors from multiple organisms, including the TEAD1 homologs AbaA ( Aspergillus nidulans), TEC1 ( Saccharomyces cerevisiae), and scalloped (sd, Drosophil...
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Notes

Acknowledgments

I wish to extend my apologies to the many authors whose contributions could not be cited due to space limitations. Where possible I have cited review articles to allow readers access to the literature. In addition, the readers may access additional information and references on TEAD via the Nature-UCSD signaling gateway: http://www.signaling-gateway.org/.

References

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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Departments of Medicine and Biochemistry & Molecular BiologyMayo ClinicRochesterUSA