Hepatovirus

Anderson, David A.; Counihan, Natalie

doi:10.1007/978-0-387-95919-1_214

David A. Anderson B.Sc, Ph.D³ &
Natalie Counihan PhD⁴

178 Accesses
1 Citations

Virion

Morphology:	Icosahedral
Envelope:	No
Diameter (nm):	27
Length (nm):	–
Structural components:	Capsid (VP0/VP2, VP3, VP1)
Buoyant density (g/mL):	1.33
Buoyant density method:
Lipid composition:
Additional information:	Capsid contains both precursor VPO and product VP2; product VP4 is not detected

Genome

Nucleic acid:	RNA
Strandedness:	Single-stranded
Polarity:	Positive-sense
Configuration:	Linear
Segment organization:	Segment No. 1 (kb):	7.5
	One segment(s):	7.5 (kb) total (calculated)
G + C content (%):	37.9
mRNA transcripts:	–
Open reading frames:
Additional information:	5′ untranslated region functions as internal ribosome entry site; genome-linked protein (VPg) covalently linked to 5′ end

Replication

Entry mechanism:	Receptor-mediated endocytosis, acid-independent
Site of transcription:	N/a
Transcriptase:	N/a
Site of genome replication:	Cytoplasm
Replicase:	Virus-encoded 3D RNA-dependent RNA polymerase
Replication intermediate:	Partially double-stranded replicative intermediate...

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Author information

Authors and Affiliations

Hepatitis Research Laboratory, Macfarlane Burnet Institute for Medical Research and Public Health, 85 Commercial Road, Melbourne, Victoria, 3004, Australia
David A. Anderson B.Sc, Ph.D
Microbial Pathogenesis, Yale University, Boyer Centre for Molecular Medicine, Section of Microbial Pathogenesis, 295 Congress Ave, New Haven, CT, 06536–0812, USA
Natalie Counihan PhD

Authors

David A. Anderson B.Sc, Ph.D
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Natalie Counihan PhD
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Corresponding author

Correspondence to David A. Anderson B.Sc, Ph.D .

Editor information

Editors and Affiliations

Buchener Str. 5a, 69429, Waldbrunn, Germany
Christian Tidona
Blumenthalstr. 9, D-69120, Heidelberg, Germany
Gholamreza Darai

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Anderson, D.A., Counihan, N. (2011). Hepatovirus. In: Tidona, C., Darai, G. (eds) The Springer Index of Viruses. Springer, New York, NY. https://doi.org/10.1007/978-0-387-95919-1_214

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DOI: https://doi.org/10.1007/978-0-387-95919-1_214
Publisher Name: Springer, New York, NY
Print ISBN: 978-0-387-95918-4
Online ISBN: 978-0-387-95919-1
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