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Potential Protective Effects of Probiotics and Prebiotics Against Colorectal Cancer

  • Philip Allsopp
  • Ian Rowland

Abstract

Colorectal cancer (CRC) is the fourth most frequent cause of cancer related mortality in the world. Approximately 944,000 new cases were diagnosed globally in 2000 and this accounts for 9.2% of all new cancer cases (IARC, 2000). In Western societies namely Europe, North America and Australasia, it is the second most prevalent cancer after lung/breast (Boyle and Langman, 2000). About 363,000 new cases were reported in Europe in 2000 and it affects 6% of men and women by age 75, in almost equal proportion.

Keywords

Lactic Acid Bacterium Resistant Starch Aberrant Crypt Focus Lactic Acid Bacterium Strain Fermented Dairy Product 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

List of Abbreviations

ACF

aberrant crypt foci

AOM

azoxymethane

CRC

Colorectal cancer

DMH

1,2-dimethylhydrazine

FOS

fructo-oligosaccharide

Glu-P-1

2-amino-6-methyldipyrido[1,2-a:3′,2′-d]imidazole

Glu-P-2

2-aminodipyrido[1,2-a:3′,2′-d]imidazole

HFA

human flora associated

IQ

2-amino-3-methyl-3H-imidazo(4,5-f)quinoline

LAB

lactic acid producing bacteria

MeIQ

2-amino3,4-dimethylimidazo[4,5-f]quinoline

MeIQx

2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline

MNNG

N-methyl-N’-nitro-N-nitrosoguanidine

NDO

non-digestible oligosaccharide

PhIP

2-amino-1-methyl-6-phenylimidazo-[4,5b]pyridine

TOS

trans-galactosylated oligosaccharide

Trp-P-1

3-amino-1,4-dimethyl-5H-pyrido-[4,3-b]indole

Trp-P-2

3-amino-1-methyl-5H-pyrido[4,3b]indole

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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Philip Allsopp
    • 1
  • Ian Rowland
    • 2
  1. 1.Northern Ireland Centre for Food and Health, Centre for Molecular BiosciencesUniversity of UlsterColeraineUK
  2. 2.Hugh Sinclair Unit for Human Nutrition, Department of Food BiosciencesUniversity of ReadingWhiteknightsUK

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