Skip to main content

The Disease Burden Due to Epilepsy in Rural China

  • Reference work entry
Book cover Handbook of Disease Burdens and Quality of Life Measures
  • 96 Accesses

Abstract:

The World Health Organization (WHO), in cooperation with the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE) launched the Global Campaign Against Epilepsy (GCAE) in an attempt to bring epilepsy “out of the shadows” and to improve the acceptability, treatment, services and prevention of epilepsy world-wide. As part of this campaign and under the auspices of the WHO and the Ministry of Health of China, a demonstration project was implemented in rural areas in six non-contiguous provinces of the People’s Republic of China (PRC). In the sample areas, the lifetime prevalence and prevalence of active epilepsy in rural China were 6.0–7.0/1,000 and 3.8–4.6/1,000 respectively. Sixty-three percent of people with active epilepsy had not received antiepileptic medication in the week before the survey (i.e., the treatment gap was 63%). The disease burden of epilepsy was measured as 2.08 Disability Adjusted Life Years (DALYs) lost per 1,000 population. The standardized mortality ratio (SMR) of people with epilepsy was 3.9 indicating that people with epilepsy are three to four times more likely to die prematurely than those in the general Chinese population. The risk in young people with epilepsy aged 15–29 years in China is particularly high.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 3,000.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 549.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Abbreviations

AED:

anti-epileptic drug

CFR:

case fatality rate

DALY:

disability adjusted life year

EMPHL:

epilepsy management at primary health level

GBD:

global burden of disease

GCAE:

global campaign against epilepsy

IBE:

International Bureau for Epilepsy

ICBERG:

International community-based epilepsy research group

ILAE:

International League Against Epilepsy

PMR:

proportional mortality rate

PRC:

People’s Republic of China

SMR:

standardized mortality ratio

WHO:

World Health Organization

YLD:

years lived with disability

YLL:

years of life lost

References

  • Cockerell OC, Johnson AL, Sander JW, Hart YM, Goodridge DM, Shorvon SD. (1994). Lancet. 344: 918–921.

    Article  PubMed  CAS  Google Scholar 

  • Ding D, Hong Z, Wang WZ, Wu JZ, de Boer HM, Prilipko L, Sander JW. (2006). Epilepsia. 47: 2032–2037.

    Article  PubMed  Google Scholar 

  • Ding D, Lu GY, Huang MS, Zhou B, Hou GQ, Zeng J, Jin MH, Zhu GX, Wang JY, Fu JH, Meng HJ, Zhao QH, Hong Z. (2004). Chin J Neurosci. 12: 122–124 (Chinese).

    Google Scholar 

  • Ding D, Wang WZ, Wu JZ, Ma GY, Dai XY, Yang B, Wang TP, Yuan CL, Hong Z, de Boer HM, Prilipko L, Sander JW. (2006). Lancet Neurol. 5: 823–827.

    Article  PubMed  Google Scholar 

  • Gaitatzis A, Sander JW. (2004). Epileptic Disord. 6: 3–13.

    PubMed  Google Scholar 

  • GBD 2000 (2000). Available from: URL: http://www3.who.int/whosis Accessed 2004.

  • Kale R. (1997). BMJ. 315: 2–3.

    PubMed  CAS  Google Scholar 

  • Kleinman A, Wang WZ, Li SC, Cheng XM, Dai XY, Li KT, Kleinman J. (1995). Soc Sci Med. 40: 1319–1330.

    Article  PubMed  CAS  Google Scholar 

  • Li SC. (1989). Chin J Nerv Ment Dis. 22: 144 (Chinese).

    CAS  Google Scholar 

  • Meinardi H, Scott RA, Reis R, Sander JW. (2001). Epilepsia. 42: 136–149.

    Article  PubMed  CAS  Google Scholar 

  • Murray CJL, Lopez AD. (1996). Global Burden of Disease and Injury Series. World Health Organization, Geneva.

    Google Scholar 

  • Scott RA, Lhatoo SD, Sander JW. (2001). Bull World Health Organ. 79: 344–351.

    PubMed  CAS  Google Scholar 

  • Wang WZ, Wu JZ, Wang DS, Chen GS, Wang TP, Yuan CL, Yang B, Zhao DH. (2002). Natl Med J China. 82: 449–452 (Chinese).

    Google Scholar 

  • Wang WZ, Wu JZ, Wang DS, Dai XY, Yang B, Wang TP, Yuan CL, Scott RA, Prilipko L, de Boer HM, Sander JW. (2003). Neurology. 60: 1544–1545.

    PubMed  CAS  Google Scholar 

  • World Health Organization. (2000). The Global Campaign Against Epilepsy – Out of the Shadows. WHO, Geneva.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2010 Springer Science+Business Media LLC

About this entry

Cite this entry

Ding, D., Wang, W.Z., Hong, Z. (2010). The Disease Burden Due to Epilepsy in Rural China. In: Preedy, V.R., Watson, R.R. (eds) Handbook of Disease Burdens and Quality of Life Measures. Springer, New York, NY. https://doi.org/10.1007/978-0-387-78665-0_92

Download citation

  • DOI: https://doi.org/10.1007/978-0-387-78665-0_92

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-78664-3

  • Online ISBN: 978-0-387-78665-0

  • eBook Packages: MedicineReference Module Medicine

Publish with us

Policies and ethics