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The Societal Costs of Anxiety and Mood Disorders: An Epidemiological Perspective

  • R. C. Kessler
  • P. S. Wang
  • H.-U. Wittchen
Reference work entry

Abstract:

This chapter reviews the epidemiological literature on the prevalence and adverse societal consequences of anxiety and mood disorders. A special emphasis is put on the recently collected data from the completed World Health Organization (WHO) World Mental Health (WMH) Surveys (Kessler and Üstün, 2008). The first section of the chapter discusses the methods used in community epidemiological surveys to estimate the prevalence and correlates of mental disorders. The next section reviews the recent worldwide epidemiological literature on the general population prevalence of anxiety and mood disorders. This is followed by reviews of recent epidemiological evidence on age-of-onset distributions, illness course, and comorbidity among the anxiety and mood disorders. The last section reviews the recent epidemiological literature on the adverse effects of anxiety and mood disorders. The evidence presented in these sections documents clearly that anxiety and mood disorders are commonly occurring, that many of them start at an early age and have a chronic-recurrent course, and that they have a number of adverse effects that make them among the most costly of all health problems from a societal perspective.

Keywords

Major Depressive Disorder Anxiety Disorder Obsessive Compulsive Disorder Mood Disorder Separation Anxiety Disorder 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

List of Abbreviations:

AOO

Age-Of-Onset

BPD

Bipolar Disorder

CDS

The National Institute of Mental Health Collaborative Depression Study

CIDI

The Composite International Diagnostic Interview

DIS

The Diagnostic Interview Schedule

DSM

The American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders

GAD

Generalized Anxiety Disorder

HARP

The Harvard/Brown Anxiety Disorders Research Program

ICD

The World Health Organization International Classification of Diseases

ICPE

The World Health Organization International Consortium of Psychiatric Epidemiology

IQR

Inter-Quartile Range

MDD

Major Depressive Disorder

NCS-R

The National Comorbidity Survey Replication

NIMH

The National Institute of Mental Health

OCD

Obsessive-Compulsive Disorder

PTSD

Post-Traumatic Stress Disorder

SAD

Separation Anxiety Disorder

WHO

World Health Organization

WMH Surveys

The World Mental Health Surveys

Notes

Acknowledgments

Preparation of this chapter was supported, in part, by grants The National Comorbidity Survey Replication (NCS-R) is supported by NIMH (U01-MH60220) with supplemental support from the National Institute on Drug Abuse (NIDA), the Substance Abuse and Mental Health Services Administration (SAMHSA), the Robert Wood Johnson Foundation (RWJF; Grant 044780), and the John W. Alden Trust. Collaborating NCS-R investigators include Ronald C. Kessler (Principal Investigator, Harvard Medical School), Kathleen Merikangas (Co-Principal Investigator, NIMH), James Anthony (Michigan State University), William Eaton (The Johns Hopkins University), Meyer Glantz (NIDA), Doreen Koretz (Harvard University), Jane McLeod (Indiana University), Mark Olfson (New York State Psychiatric Institute, College of Physicians and Surgeons of Columbia University), Harold Pincus (University of Pittsburgh), Greg Simon (Group Health Cooperative), Michael Von Korff (Group Health Cooperative), Philip Wang (Harvard Medical School), Kenneth Wells (UCLA), Elaine Wethington (Cornell University), and Hans-Ulrich Wittchen (Max Planck Institute of Psychiatry; Technical University of Dresden). The views and opinions expressed in this report are those of the authors and should not be construed to represent the views of any of the sponsoring organizations, agencies, or U.S. Government. A complete list of NCS publications and the full text of all NCS-R instruments can be found at http://www.hcp.med.harvard.edu/ncs. Send correspondence to ncs@hcp.med.harvard.edu.

The NCS-R is carried out in conjunction with the World Health Organization World Mental Health (WMH) Survey Initiative. We thank the staff of the WMH Data Collection and Data Analysis Coordination Centres for assistance with instrumentation, fieldwork, and consultation on data analysis. These activities were supported by the National Institute of Mental Health (R01 MH070884), the John D. and Catherine T. MacArthur Foundation, the Pfizer Foundation, the US Public Health Service (R13-MH066849, R01-MH069864, and R01 DA016558), the Fogarty International Center (FIRCA R03-TW006481), the Pan American Health Organization, Eli Lilly and Company, Ortho-McNeil Pharmaceutical, Inc., GlaxoSmithKline, and Bristol-Myers Squibb. A complete list of WMH publications can be found at http://www.hcp.med.harvard.edu/wmh/.

Portions of this chapter appeared previously in Kessler, R.C., Ruscio, A.M., Shear, K., Wittchen, H.-U. (in press). The epidemiology of anxiety disorders. In M.M. Antony and M.B. Stein (Eds.), Handbook of Anxiety and the Anxiety Disorders. New York: Oxford University Press Oxford University Press; Wang, P.S., Kessler, R.C. (2005). Global burden of mood disorders. In D. Stein, D. Kupfer and A. Schatzberg (Eds.), Textbook of Mood Disorders (pp. 55–67). Washington DC: American Psychiatric Publishing, Inc. American Psychiatric Publishing, Inc. 2005; Kessler, R.C. (2007). The global burden of anxiety and mood disorders: Putting the European Study of the Epidemiology of Mental Disorders (ESEMeD) findings into perspective. Journal of Clinical Psychiatry 68 (suppl. 2), 10–19, Physicians Postgraduate Press, Inc. 2007. All used with permission.

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Copyright information

© Springer Science+Business Media LLC 2010

Authors and Affiliations

  • R. C. Kessler
  • P. S. Wang
  • H.-U. Wittchen

There are no affiliations available

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