Plasma levels of the amino acid homocysteine may be affected by certain vitamins. Epidemiological studies have shown that elevated plasma levels of homocysteine are correlated with a higher risk of coronary heart disease, strokes, and peripheral vascular disease. However, in controlled trials there has been no morbidity or mortality benefit to lowering plasma homocysteine levels with megadoses of vitamins B6, B12 and Folate.


Public Health High Risk Heart Disease Coronary Heart Disease Plasma Level 
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