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Handbook of Disease Burdens and Quality of Life Measures pp 949–964Cite as

Burden of Cerebrovascular Diseases (Stroke) in Serbia

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Abstract:

The purpose of the study was to provide a comprehensive review of the most important features regarding burden of cerebrovascular disease (i.e., stroke) in Serbia.

In Serbia, stroke is the leading cause of mortality in females (20.8% of all deaths) and the second cause in males (15.5%). The crude mortality rate from stroke in Serbia in 2000 was 248.8/100,000, and age-adjusted rate 122.6/100,000 (using Segi’s world standard population), while in the Belgrade population (period of observation: 1989–2003), the average standardized mortality rates (using Segi’s world standard population) for all stroke subtypes were 90.8/100,000 overall, 98.0/100,000 for men and 82.4/100,000 for women. The average standardized stroke mortality rates in Belgrade changed in the period 1989–2003 for both genders, the highest values being registered in the period 1994–1998 and the lowest in the period 1989–1993.

The burden of cerebrovascular disease in Serbia without Kosovo and Metohia in 2000, expressed in terms of as DALY was 65,795 in men and 70,295 in women (136,090 DALY for the total population). Stroke is the second leading cause of DALY for males, after IHD, and the leading cause for females. In Serbia 2000, YLL rates per 1,000 for stroke were lower in males (15.6/1,000) than in females (16.7/1,000). Moreover, in males stroke was the second leading single cause of premature YLL (13% of total YLL), while in females it ranked first (18% of total YLL). Rates of YLD per 1,000 were 2.3 for males and 1.4 for females. Hypertension as one of the most important risk factors for stroke was responsible for 13.3% of the total YLL in Serbia 2,000 in females and 9.7% in males. The proportion of total DALY calculated for stroke due to hypertension was higher for females (48.65%) than for males (40.51%).

In conclusion, the important findings obtained in the SBDS should be used as a guide for implementing preventive strategies, as well as for evaluating the scope of future gains obtained by reducing exposure to known risk factors for cerebrovascular disease.

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Abbreviations

CT:

computed tomography

CVD:

cerebrovascular diseases

DALY:

disability adjusted life years

ICD:

International Classification of Diseases

ICH:

intracerebral hemorrhage

IHD:

ischemic heart disease

MONICA:

Monitoring of Trends and Determinants in Cardiovascular Disease

MRI:

magnetic resonance imaging

SAH:

subarachnoid hemorrhage

SBDS:

Serbian Burden of Disease Study

YLD:

years lived with disability

YLL:

years of life lost

WHO:

World Health Organization

References

  • Adanja B, Gledovic Z, Pekmezovic T, Vlajinac H, Jarebinski M, Zivaljevic V, Pavlovic M. (2000). Dig Liver Dis. 32: 386–391.

    Article  PubMed  CAS  Google Scholar 

  • American Hear Association. (2008). Heart Disease and Stroke Statistics. 2008 Update At-a-Glance.

    Google Scholar 

  • Atanackovic Markovic Z, Bjegovic V, Jankovic S, Kocev N, Laaser U, Marinkovic J, Markovic Denic Lj, Pejin Stokic Lj, Penev G, Stanisavljevic D, Santric Milicevic M, Saulic A, Sipetic Grujicic S, Terzic Supic Z, Vlajinac H. (2003). The Burden of Disease and Injury in Serbia. Ministry of Health of Republic of Serbia, Belgrade.

    Google Scholar 

  • Avendano M, Kunst AE, van Lenthe F, Bos V, Costa G, Valkonen T, Cardano M, Harding S, Borgan JK, Glickman M, Reid A, Mackenbach JP. (2005). Am J Epidemiol. 161: 52–61.

    Article  PubMed  CAS  Google Scholar 

  • Bevan G, Hollinghurst S, Raftery J, Gold L, Stevens A, Smithies A, Spurgeon R, Bowie C. (1998). The South and West DALYs Project: Developing a powerful tool for health care planning. Somerset Health Authority, Wellsprings Road, Taunton, Somerset.

    Google Scholar 

  • Cayuela A, Rodriguez S, Iglesias P, Lapetra J, Gil-Pelralta A. (2002). Neuroepidemiology. 21: 142–147.

    Article  PubMed  Google Scholar 

  • Department of Human Services. (1999). The Victorian Burden of Disease Study: Mortality. Public Health and Development Division, Department of Human Services, Melbourne.

    Google Scholar 

  • Feigin VL, Lawes CMM, Bennett DA, Anderson CS. (2003). Lancet Neurol. 2: 43–53.

    Article  PubMed  Google Scholar 

  • Francescutti C, Mariotti S, Simon G, D’errigo P, Di bidino R. (2005). Disabil Rehabil. 27: (5)229–240.

    Article  PubMed  Google Scholar 

  • Institute of Public Health of Serbia. (2001). 2000 Population Health Survey in Serbia. Ministry of Health, Republic of Serbia, Belgrade.

    Google Scholar 

  • Jakovljevic D, Sarti C, Silvenius J, Torppa J, Mahonen M, Immonen-Raiha P, Kaarsalo E, Alhainen H, Kuulasmaa K, Tuomilehto J, Puska P, Salomaa V. (2001). Stroke. 32: 1492–1498.

    PubMed  CAS  Google Scholar 

  • Jankovic S, Vlajinac H, Bjegovic V, Marinkovic J, Sipetic-Grujicic S, Markovic-Denic LJ, Kocev N, Santric-Milicevic M, Terzic-Supic Z, Maksimovic N, Laaser U. (2007). Eur J Publ Health. 17: 80–85.

    Article  Google Scholar 

  • Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJL. (2006). Lancet. 367: 1747–1757.

    Article  PubMed  Google Scholar 

  • Mariotti S, D’Errigo P, Mastroeni S, Freeman K. (2003). Eur J Epidemiol. 18: 513–521.

    Article  PubMed  Google Scholar 

  • Mathers C, Stein C, Ma Fat D, Rao C, Inoue M, Tomijima N, Bernard C, Lopez A, Murray C. (2002). Global Burden of Disease 2000: Version 2 Methods and Results. GPE Discussion Paper No. 50. World Health Organization, Geneva.

    Google Scholar 

  • Mathers CD, Theo Vos E, Stevenson CE, Begg SJ. (2000). Med J Aust. 172: 592–596.

    PubMed  CAS  Google Scholar 

  • Mathers CD, Theo Vos E, Stevenson CE, Begg SJ. (2001). Bull World Health Organ. 79: 1076–1084.

    PubMed  CAS  Google Scholar 

  • Melse JM, Essink-Bot ML, Kramers PGN, Hoeymans N, on behalf of the Dutch Burden of Disease Group. (2000). Am J Publ Health. 90: 1241–1247.

    Article  CAS  Google Scholar 

  • Murray CJL, Lopez AD, (eds.) (1996). The global burden of disease: a comprehensive assessment of mortality and disability from diseases, injures and risk factors in 1990 and projected to 2020. In: Global Burden of Disease and Injury Series. Harvard University Press, Cambridge.

    Google Scholar 

  • Murray CJL, Lopez AD. (1997a). Lancet. 349: 1498–1504.

    Article  PubMed  CAS  Google Scholar 

  • Murray CJL, Lopez AD. (1997b). Lancet. 349: 1269–1276.

    Article  PubMed  CAS  Google Scholar 

  • Murray CJL, Lopez AD. (1997c). Lancet. 349: 1436–1442.

    Article  PubMed  CAS  Google Scholar 

  • Murray CJL, Lopez AD, Mathers CD, Stein C. (2001). The Global Burden of Disease 2000 project: aims, methods and data sources. World Health Organization, Geneva. Available on the worldwide web at www.who.int/evidence

  • Pajunen P, Paakkonen R, Hamalainen H, Keskimäki I, Laatikainen T, Niemi M, Rintanen H, Salomaa V. (2005). Stroke. 36: 244–248.

    Article  PubMed  Google Scholar 

  • Pekmezovic T, Kisic Tepavcevic D, Jarebinski M, Kostic M, Bumbasirevic Lj. (2007). Cerebrovasc Dis. 24: 191–195.

    Article  PubMed  Google Scholar 

  • Pekmezovic T, Kisic Tepavcevic D, Jarebinski M, Kostic M, Bumbasirevic Lj. (2008). Clin Neurol Neurosurg. 110: 51–57.

    Article  PubMed  Google Scholar 

  • Peltonen M, Asplund K. (1996). Stroke. 27: 1981–1985.

    PubMed  CAS  Google Scholar 

  • Rosamond W, Flegal K, Friday G, Furie K, Go A, Greenlund K, Haase N, Ho M, Howard V, Kissela B, Kittner S, Lloyd-Jones D, McDermott M, Meigs J, Moy C, Nichol G, O’Donnell CJ, Roger V, Rumsfeld J, Sorlie P, Steinberger J, Thom T, Wasserthiel-Smoller S, Hong Y. for the American Heart Association Statistics Committee and Stroke Statistics Subcommittee.(2007). Circulation. 115: e69–e171.

    Article  PubMed  Google Scholar 

  • Sarti C, Rastenyte D, Cepatis Z, Tuomilehto J. (2000). Stroke. 31: 1588–1601.

    PubMed  CAS  Google Scholar 

  • Stegmayr B, Vinogradova T, Malyutina S, Peltonen M, Nikitin Y, Asplund K. (2000). Stroke. 31: 2–8.

    PubMed  CAS  Google Scholar 

  • Sturgeon JD, Folsom AR. (2006). Neuroepidemiology. 28: 39–45.

    Article  PubMed  Google Scholar 

  • Thorvaldsen P, Asplund K, Kuulasmaa K, Rajakangas AM, Schroll M. (1995). Stroke. 26: 361–367.

    PubMed  CAS  Google Scholar 

  • Thorvaldsen P, Kuulasmaa K, Rajakangas AM, Rastenyte D, Sarti C, Wilhelmsen L. (1997). Stroke. 28: 500–506.

    PubMed  CAS  Google Scholar 

  • Tosic O. (1992). Lancet. 340: 295–296.

    Article  Google Scholar 

  • Truelsen T, Piechowski-Jozwiak B, Bonita R, Mathers C, Bogousslavsky J, Boysen G. (2006). Eur J Neurol. 13: 581–598.

    Article  PubMed  CAS  Google Scholar 

  • Vlajinac H, Marinkovic J, Kocev N, Adanja B, Pekmezovic T, Sipetic S, Jovanovic D. (1997). J Epidemiol Commun Health. 51: 172–174.

    Article  CAS  Google Scholar 

  • Vlajinac H, Marinkovic J, Kocev N, Adanja B, Sipetic S, Pekmezovic T, Zivaljevic V. (2000). Srp Arh Celok Lek. 128(9–10): 309–315.

    PubMed  CAS  Google Scholar 

  • Vlajinac H, Marinkovic J, Kocev N, Sipetic S, Bjegovic V, Jankovic S, Stanisavljevic D, Markovic-Denic Lj, Maksimovic J. (2008). Public Health. 122: 277–284.

    Article  PubMed  Google Scholar 

  • Vlajinac H, Sipetc S, Saulic A, Atanackovic Z, Marinkovic J, Bjegovic V. (2006). Eur J Cadiovasc Prev Rehabil. 13: 753–759.

    Article  Google Scholar 

  • World Health Organization. (1997). World Health Report 1997. Conquering Suffering, Enriching Humanity. World Health Organization, Geneva.

    Google Scholar 

  • World Health Organization. (2004). Global burden of stroke. In: Atlas of Heart Disease and Stroke. World Health Organization, Geneva, pp. 50.

    Google Scholar 

  • World Health Organization. (2006). Neurological Disorders: Public Health Challenges. World Health Organization, Geneva.

    Google Scholar 

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Authors
  1. T. Pekmezovic
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  2. H. Vlajinac
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  3. S. Sipetic-Grujicic
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  4. N. Kocev
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  5. D. K. Tepavcevic
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  6. L. B. Bumbasirevic
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Editor information

Editors and Affiliations

  1. Dept. Nutrition and Dietetics Nutritional Sciences Research Division School of Biomedical & Health Sciences, King's College London, Franklin‐Wilkins Building 150 Stamford Street, SE1 9NH, London, UK

    Victor R. Preedy (Prof.) (Prof.)

  2. Mel and Enid Zuckerman College of Public Health, University of Arizona, Health Science Center 1295 N. Martin, P.O. Box 245155, 85724-5155, Tucson, AZ

    Ronald R. Watson (Prof.) (Prof.)

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Pekmezovic, T., Vlajinac, H., Sipetic-Grujicic, S., Kocev, N., Tepavcevic, D.K., Bumbasirevic, L.B. (2010). Burden of Cerebrovascular Diseases (Stroke) in Serbia. In: Preedy, V.R., Watson, R.R. (eds) Handbook of Disease Burdens and Quality of Life Measures. Springer, New York, NY. https://doi.org/10.1007/978-0-387-78665-0_54

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  • DOI: https://doi.org/10.1007/978-0-387-78665-0_54

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-78664-3

  • Online ISBN: 978-0-387-78665-0

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