Circulating Endothelial Progenitor Cells

Reference work entry


This term is used to describe a cell population that can be isolated from circulating mononuclear cells, bone marrow, and cord blood. These cells showed expression of various endothelial markers, they have the ability to mature into endothelial cells and have a physiological role in the repair of endothelial lesions. Experimentally, when these cells are injected into animal models with ischemia, they are rapidly incorporated into sites of neovascularization. The levels of circulating endothelial progenitor cells correlate inversely with the degree of endothelial dysfunction in humans at various degrees of cardiovascular risk.


Public Health Bone Marrow Endothelial Cell Animal Model Cell Population 
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© Springer Science+Business Media LLC 2010

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