Handbook of Disease Burdens and Quality of Life Measures pp 4169-4169 | Cite as
Circulating Endothelial Progenitor Cells
This term is used to describe a cell population that can be isolated from circulating mononuclear cells, bone marrow, and cord blood. These cells showed expression of various endothelial markers, they have the ability to mature into endothelial cells and have a physiological role in the repair of endothelial lesions. Experimentally, when these cells are injected into animal models with ischemia, they are rapidly incorporated into sites of neovascularization. The levels of circulating endothelial progenitor cells correlate inversely with the degree of endothelial dysfunction in humans at various degrees of cardiovascular risk.