Malignant Bone Disease Due to Neoplasia


Metastatic bone diseases are cancers that started in another location and spread to the bones. Metastasis of tumor cells to bone requires a cascade of events involving detachment from the primary tumor site, invasion of the vasculature, migration and adherence to distant capillaries of the bone, extravasation, and proliferation.


Public Health Tumor Cell Primary Tumor Bone Metastasis Social Policy 
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© Springer Science+Business Media LLC 2010

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