Quality of Life Measures in Fibromyalgia

  • N. Gusi
  • Pedro R. Olivares
  • J. Carmelo Adsuar
  • A. Paice
  • P. Tomas-Carus
Reference work entry


 Fibromyalgia (FM) is a chronic, widespread and painful disorder of affecting approximately 2–3% of the general population, with an approximately 90% female preponderance. Health-related quality of life (HRQoL) outcome assessment is crucial in patients with FM because of their multiple symptoms, which include chronic pain, fatigue, weakness, hyperalgesia, secondary depression and allodynia. These can produce substantial work disability and disruptions in quality of life, with impaired social and family functioning. The diverse symptomatology of patients with FM may be assessed holistically using HRQoL questionnaires. These questionnaires can be classified into generic measures and disease-specific measures. SF-36 and EQ-5D represent the generic tools most commonly used in FM studies, but other questionnaires include the Sickness Impact Profile (SIP), Nottingham Health Profile (NHP), Health Utilities Index (HUI) and Quality of Well Being Index (QWB). The fibromyalgia-specific instruments most commonly used are the Fibromyalgia Impact Questionnaire (FIQ) and FibroFatigue Scale (FFS). To date, few cost-utility analyses exist. Examples include EQ-5D and SF-6D. Using these questionnaires it has been shown that patients with FM perform worse than other chronic pain patients, such as those with rheumatoid arthritis and chronic back pain, specifically when vitality, bodily pain, mental health, social functioning, mobility, usual activities, pain/discomfort and anxiety/depression scores were analyzed. The impact of illness, adjusted for co-morbidities, increased in younger adults but the symptomatology decreased with age.


Chronic Fatigue Syndrome Chronic Back Pain Fibromyalgia Impact Questionnaire Nottingham Health Profile Health Utility Index 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

List of Abbreviations:


American College of Rheumatology


 arthritis impact measurement scales


 chronic fatigue syndrome


Euroqol five item Questionnaire


The EQ-5D Visual Analogue Scale


the  fibromyalgia and chronic fatigue syndrome rating scale


The  Fibromyalgia Impact Questionnaire




 Stanford Health Assessment Questionnaire


Nottingham Health Profile


quality-adjusted life-years


quality of well being index


health-related quality of life


the health utilities index


the health state descriptive system questionnaire


Short Form Health Survey questionnaire with 36 questions


6-item Short Form Health Survey Questionnaire


sickness impact profile


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Copyright information

© Springer Science+Business Media LLC 2010

Authors and Affiliations

  • N. Gusi
    • 1
  • Pedro R. Olivares
    • 1
  • J. Carmelo Adsuar
    • 1
  • A. Paice
    • 2
  • P. Tomas-Carus
    • 3
  1. 1.Faculty of Sports SciencesUniversity of ExtremaduraNashvilleSpain
  2. 2.Department of Clinical Biochemistry and Nutrition and DieteticsKing’s College School of MedicineNashvilleLondon, UK
  3. 3.Department of Sports and HealthUniversity of EvoraNashvillePortugal

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