Issues in Quality of Life Assessment in Schizophrenia

  • C. R. Martin
  • M. Fleming
Reference work entry


 Quality of Life is an important aspect of everyday functioning to patients with a primary diagnosis of  schizophrenia. The multifactorial nature of schizophrenia enmeshed within a biopsychosocial phenomena and the impact of pharmacological therapy makes the accurate assessment of quality of life in this group highly complex. Consequently, the development and evaluation of instruments designed to assess the concept is vital in this group. This chapter will assess the issues involved in assessing quality of life in this unique group of patients.


Negative Symptom Positive Symptom Affective Disturbance Mental Health Service User 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

List of Abbreviations:


lancashire quality of life scale


positive and  negative symptom scale


quality of life scale


quality of life


short-form 36


  1. Andreason NC, Olsen S. (1982). Arch Gen Psychiat. 39(7).Google Scholar
  2. APA. (1994). DSM-IV. Diagnostic and Statistical Manual of Mental Disorders, 4th ed. American Psychiatric Association. Washington, DC.Google Scholar
  3. Auquier P, Simeoni MC, Sapin C, Reine G, Aghababian V, Cramer J, Lancon C. (2003). Schizophr Res. 63: 137–149.PubMedCrossRefGoogle Scholar
  4. Awad GA, Voruganti LNP, Heslegrave RJ. (1997). Pharmacoeconomics. Jan, 11: 32–47.PubMedCrossRefGoogle Scholar
  5. Baker F, Intagliata J. (1982). Eval Program Plann. 5: 69–79.PubMedCrossRefGoogle Scholar
  6. Becker M, Diamond R, Sainfort F. (1993). Qual Life Res. 2: 239–251.PubMedCrossRefGoogle Scholar
  7. Bentall RP. (2003). Madness Explained: Psychosis and Human Nature. Penguin, London.Google Scholar
  8. Bergner M, Bobbit R, Carter W. (1981). Medical Care. 19: 787–805.PubMedCrossRefGoogle Scholar
  9. Bigelow DA, McFarland BH, Olson MM. (1991). Community Ment Health J. 27: 43–55.PubMedCrossRefGoogle Scholar
  10. Bjorkman T, Svensson B. (2005). Nord J Psychiat. 59(4): 302–306.(5)CrossRefGoogle Scholar
  11. Bowers D, House A, Owens D. (2006). Understanding Clinical Papers, 2nd ed. Scholar
  12. Bowling A. (1997). Measuring Health. Open University Press, Buckingham.Google Scholar
  13. Browne S, Clarke M, Gervin M, Waddington JL, Larkin C, O’Callaghan E. (2000). Br J Psychiat. 176: 173–176.CrossRefGoogle Scholar
  14. Clifford PI, Kastavdakis KA, Lyle JL, Fultz J, Allen JG & Graham P. (2002). J Ment Health. 11: 389–404.CrossRefGoogle Scholar
  15. Cohen J. (1960). Educ Psychol Meas. 20: 37–46.CrossRefGoogle Scholar
  16. Cronbach LJ. (1951). Psychometrika. 16: 297–334.CrossRefGoogle Scholar
  17. Doyle M, Flanagan S, Browne S, Clarke M, Lydon D, Larkin C, O’Callaghan E. (1999). Acta Psychiatr Scand. 99: 466–472.PubMedCrossRefGoogle Scholar
  18. Duggan M, Ford R, Hill R. (1997). Pulling Together: The Future Roles of and Training of Mental Health Staff. Sainsbury Centre for Mental Health, London.Google Scholar
  19. Eack SM, Newhill CE. (2007). Schizophr Bull. 33: 1225–1237.PubMedCrossRefGoogle Scholar
  20. EuroQoL Group. (1990). Health Policy. 16: 199–208.CrossRefGoogle Scholar
  21. Fakhoury W, Kaiser W, Roeder-Wanner UU, Priebe S. (2002). Schizophr Bull. 28: 319–327.PubMedGoogle Scholar
  22. Goldstein J, Kreisma D. (1998). Psychol Med. 18: 861–872.CrossRefGoogle Scholar
  23. Goldstein J, Lewine R. (2000). Overview of Sex Differences in Schizophrenia. In: Castle D, McGrath J, Kulkharni J (eds.) Women and Schizophrenia. Cambridge University Press.Google Scholar
  24. Harding CM, Brooks GW, Ashikaga T, Strauss JS, Breier A. (1987). Am J Psychiat. 144: 727–735.PubMedGoogle Scholar
  25. Heinrichs DW, Hanlon TE, Carpenter WT. (1984). Schizophr Bull. 10: 388–398.PubMedGoogle Scholar
  26. Hewitt J. (2007). Int J Ment Health Nurs. 16: 2–14.PubMedCrossRefGoogle Scholar
  27. Hogg L. (1996) Psychological Treatments for Negative Symptoms. In: Haddock G, Slade PD (eds.) Cognitive-Behavioural Interventions with Psychotic Disorders. Routledge, London.Google Scholar
  28. Kaiser W, Priebe S, Barr W, Hoffman K, Iserman M, Roder-Wanner UU, Huxley P. (1997). Psychiat Res. 66: 153–166.CrossRefGoogle Scholar
  29. Katsavdakis KA, Clifford PI, Evans RB, Graham P, Allen JG, Sargent J, Lyle J, Frager DC. (1999). Bull Menninger Clini. 63: 366–387.Google Scholar
  30. Landis JR, Koch GG. (1977). Biometrics. 33: 159–174.PubMedCrossRefGoogle Scholar
  31. Lehman AF, Possidente S, Hawker F. (1986). Qual Life Res. 6: 21–26.Google Scholar
  32. Martin CR, Allan R. (2007). Psychol Health Med. 12(2): 126–134.PubMedGoogle Scholar
  33. Nadalet L, Kohl FS, Pringuey D, Berthier F. (2005). Schizophr Res. 76: 73–81.PubMedCrossRefGoogle Scholar
  34. NICE. (2002). Schizophrenia, Core interventions in the treatment and management of schizophrenia in primary and secondary care. National Institute for Clinical Excellence, Clinical Guideline 1, London.Google Scholar
  35. Norman RMG, Malla A, McClean T, Voruganti LPN, Cortese L, McIntosh E, Cheng S, Rickwood A. (2000). Acta Psychiatrica Scandinavica. 102: 303–309.PubMedCrossRefGoogle Scholar
  36. Oliver JPJ. (1991). The Social Care Directive: The Development of a Quality of Life Profile for Use in Community Services for the Mentally Ill. Soc Work Soc Sci Rev. 3: 5–45.Google Scholar
  37. Oliver J, Huxley P, Bridges K (eds.). (1996). Quality of Life and Mental Health Services. Routledge, London.Google Scholar
  38. Oliver JPJ, Huxley PJ, Preibe S, Kaiser W. (1997). Soc Psychiat Psychiatr Epidemiol. 32: 76–83.CrossRefGoogle Scholar
  39. Orley J, Saxena S, Herrman H. (1998). Quality of Life and Mental Illness. Br J Psychiat. 172: 291–283.CrossRefGoogle Scholar
  40. Priebe S, Roder-Warner U, Kaiser W. (1999). Int J Soc Psychiat. 45: 7–12.PubMedCrossRefGoogle Scholar
  41. Priebe S, Roeder-Wanner UU, Kaiser W. (2000). Psychol Med. 30: 225–230.PubMedCrossRefGoogle Scholar
  42. Ring N, Tantam D, Montague L. (1991). Acta Psychiatrica Scandanavica. 84(6): 489–496.CrossRefGoogle Scholar
  43. Ruggeri M, Warner R, Bisoffi G, Fontecedro L. (2001). Br J Psychiat. 178: 268–275.CrossRefGoogle Scholar
  44. Ruggeri M, G0ater R, Bisoffi G, Barbui C, Tansella M. (2002). Acta Psychiatrica Scandanavica. 105: 131–140.CrossRefGoogle Scholar
  45. Slade M, Leese M, Cahill S, Thornicroft G, Kuipers E. (2005). Br J Psychiat. 187: 256–261.CrossRefGoogle Scholar
  46. Stein LI, Test MA. (1980). Arch Gen Psychiat. 37: 392–397.PubMedGoogle Scholar
  47. Voruganti L, Heslegrave R, Awad AG, Seeman MV. (1998). Psychol Med. 28: 165–172.PubMedCrossRefGoogle Scholar
  48. Ware JE, Snow KK, Kosinski MK, Gandek B. (1993). The SF-36 Health Survey Manual and Interpretation Guide. The Health Institute, New England Medical Centre, Boston, MA.Google Scholar
  49. WHOQOL Group. (1998). Soc Sci Med. 46: 1569–1585.CrossRefGoogle Scholar
  50. Wilkinson G, Hesdon B, Wild D, Cookson R, Farina C, Sharma V, Fitzpatrick R, Jenkinson C. (2000). Br J Psychiat. 177: 42–46.CrossRefGoogle Scholar
  51. Wykes T, Sturt E. (1986). Br J Psychiat. 148: 1–11.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media LLC 2010

Authors and Affiliations

  • C. R. Martin
  • M. Fleming

There are no affiliations available

Personalised recommendations