Health-Related Quality of Life in Obsessive-Compulsive Disorder Subjects and their Relatives [1]: Overview

  • U. Albert
  • G. Maina
  • F. Bogetto
Reference work entry


 Obsessive-Compulsive Disorder (OCD) is a severe and disabling condition that impairs quality of life in several mental and physical domains: results of the literature are consistent in indicating a poorer quality of life as compared to community norms worldwide; concerning functioning, the areas most affected are social relationships and family functioning. Studies that compared functioning and quality of life across different mental disorders consistently found that OCD compromises quality of life to a similar degree as schizophrenia. Severity of obsessive-compulsive and comorbid depressive symptoms predicts a poorer quality of life in OCD patients, while age, gender, age at onset, or duration of the disorder do not influence quality of life.

Treatments are associated with significant improvements in quality of life; however, several studies failed to find a significant association between improvements in obsessive-compulsive symptoms and quality of life changes and other could identify a subgroup of patients with significant response in terms of reduction in symptoms but minimal improvement in quality of life. It is still to be determined whether these subjects could be offered additional interventions such as vocational rehabilitation or social skills training. Further studies are strongly needed to understand which baseline characteristics could predict quality of life improvements with treatment.

OCD impairs quality of life even in relatives of OCD patients. This impairment appears to be mediated through accommodation of the relatives to obsessive-compulsive symptoms of the patients and through the burden due to consequences of living with and caring for people with a chronic and disabling disease. This area of research is highly neglected; preliminary investigations suggest that family involvement in treatment through psychoeducation is effective in reducing perceived burden and improving quality of life and might also be effective in ameliorating obsessive-compulsive symptoms of the patients, although this need to be demonstrated.


Life Satisfaction Vocational Rehabilitation Satisfaction With Life Scale Community Norm Social Skill Training 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

List of Abbreviations:


Body Dysmorphic Disorder


Cognitive-behavioral Group Therapy


Cognitive-Behavioral Therapy


Disability Adjusted Life Years


Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition


Family Accommodation Questionnaire


Family Accommodation Scale


Generalized Anxiety Disorder


Hamilton Rating Scale for Depression


Health-Related Quality of Life


International Classification of Diseases-10th Edition


Illness Intrusiveness Rating Scale


Independent Living Skills Survey


Lancashire Quality of Life Profile


Major Depressive Disorder


Obsessive-Compulsive Disorder


Panic Disorder


Quality of Life Enjoyment and Satisfaction Questionnaire


Quality of Life


Quality of Life Inventory


Social Adjustment Scale


Social Adjustment Scale Self Report


Sheehan Disability Scale


Medical Outcomes Study 36-Item Short-Form Health Survey


Social Phobia


Satisfaction with Life Scale


United States


United States of America


World Health Organization


World Health Organization Quality of Life-Brief Version


Yale-Brown Obsessive-Compulsive Scale


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© Springer Science+Business Media LLC 2010

Authors and Affiliations

  • U. Albert
  • G. Maina
  • F. Bogetto

There are no affiliations available

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