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Health-Related Quality of Life in Adults with Systemic Lupus Erythematosus

  • L-S. Teh
  • K. McElhone
  • J. Abbott
Reference work entry

Abstract:

 Systemic lupus erythematosus (SLE) is an uncommon autoimmune multi-system disease that tends to affect young women of child-bearing age. Nevertheless, it can have a significant impact on the  health-related quality of life (HRQOL) of patients comparable to that of more common rheumatological and medical illnesses. It is essential to measure HRQOL which captures the patients’ perspective of the impact of SLE on their lives in addition to disease activity and damage when assessing the outcomes of the patients. The most popular questionnaires for assessing HRQOL in SLE are the generic measures (Generic HRQOL measures), in particular the SF-36. However, major strides recently have seen the development and evaluation of SLE-specific measures which have the added quality that they assess issues more pertinent to patients with SLE and thus may be more sensitive to the changes in HRQOL. If this is so, SLE-specific HRQOL measures may be more useful for assessing outcomes in clinical trials of new interventions for SLE.

Keywords

Systemic Lupus Erythematosus Systemic Lupus Erythematosus Patient Damage Index Poor HRQOL Good Internal Reliability 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

List of Abbreviations:

ACR

American College of Rheumatology

AIMS

arthritis impact measurement scale

Anti-C1q

anti complement 1q

Anti-dsDNA

anti double-stranded deoxyribonucleic acid

Anti-RNA

anti ribonucleic acid

Anti-SSA/SSB

anti Sjogren’s syndrome A/B

BILAG

British Isles Lupus Assessment Group

ECLAM

European Consensus lupus activity measure

EuroQOL

European quality of life

HRQOL

health-related quality of life

LupusQoL

lupus quality of life

QOL

quality of life

QOLS

quality of life scale

SF-20

short form-20

SF-36

short form-36

SIP

sickness impact profile

SIS

SLE index score

SLAM

systemic lupus activity measure

SLE

systemic lupus erythematosus

SLEDAI

systemic lupus erythematosus disease activity index

SLICC-ACR-DI

systemic lupus international collaborating clinics, American college of rheumatology damage index

SLE-QOL

systemic lupus erythematosus quality of life

SSC

SLE symptom checklist

SLEQOL

systemic lupus erythematosus quality of life

VAS

visual analogue scale

WHOQOL-Bref

World Health Organisation quality of life – abbreviated version

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Copyright information

© Springer Science+Business Media LLC 2010

Authors and Affiliations

  • L-S. Teh
  • K. McElhone
  • J. Abbott

There are no affiliations available

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