Advertisement

Quality of Life and Financial Measures in HIV/AIDS in Southern Africa

  • M. O. Bachmann
  • G. Louwagie
  • L. R. Fairall
Reference work entry

Abstract:

Several generic quality of life measures have been used in Southern African studies of HIV/AIDS, usually after translation of instruments developed in high income countries. The EuroQOL (EQ5D) instrument was used most often, usually accompanied by the VAS. It was also used in several cost utility analyses, for which it is especially useful. Other quality of life measures (FLI-C, SF36, WHO-QOL and HAT-QOL) were used infrequently. Locally developed instruments were also uncommon and included the Kaposi’s Sarcoma Module, the Satisfaction with Life Domains and Overall Satisfaction with Life and Global Happiness instruments. All of these measures were shown to be sensitive to the presence or absence of AIDS, to different levels of AIDS severity, or to treatment effects. Only the EQ5D and SF36 have been formally evaluated in terms of reliability. Several other instruments demonstrated internal consistency (that is, their components were correlated with each other). Economic studies of HIV/AIDS most commonly investigated the cost effectiveness of interventions, especially provision of antiretroviral treatment and prevention of mother to child transmission of HIV. They used either original data from patient cohorts, or models based on evidence obtained elsewhere. Other studies have investigated the economic impact of HIV/AIDS on households and businesses. A  cohort study showed that household expenditure was more sensitive to AIDS effects than household income was. In this rapidly growing area, valid locally translated instruments are increasingly available for use by researchers, while high quality evidence from cohort studies grows.

Keywords

Life Satisfaction Life Domain Life Measure EQ5D Index Female Condom 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

List of Abbreviations:

AIDS

acquired immunodeficiency syndrome

ART

antiretroviral treatment

DALY

disability-adjusted life year

EQ5D

EuroQOL 5 dimensions

FLI-C

functional living index – cancer

HIV

human immunodeficiency virus

HAT-QOL

HIV/AIDS-targeted quality of life

KSM

Kaposi’s sarcoma module

PMTCT

prevention of mother to child transmission of HIV

SF36

medical outcomes study short form 36

UNAIDS

Joint United National Programme on AIDS

VAS

visual analogue scale

References

  1. Bachmann MO. (2006). AIDS Care. 18: 109–120.PubMedCrossRefGoogle Scholar
  2. Bachmann MO, Booysen F. (2003). BMC Publ Health. 3: 14.CrossRefGoogle Scholar
  3. Bachmann MO, Booysen F. (2004). AIDS Care. 16: 817–826.PubMedCrossRefGoogle Scholar
  4. Bachmann MO, Booysen F. (2006). AIDS. 20: 1861–1867.PubMedCrossRefGoogle Scholar
  5. Badri M, Cleary S, Maartens G, Pitt J, Bekker LG, Orrell C, Wood R .(2006a). Antivir Ther. 11: 63–72PubMedGoogle Scholar
  6. Badri M, Maartens G, Mandalia S, Bekker LG, Penrods JR, Platts RW, Wood R, Becks EJ. (2006b). PLOS Med 3(1): e4.PubMedCrossRefGoogle Scholar
  7. Booysen F, Berg S. Van Der (2005). S Afr J Econ. 73(s1): 545–563.CrossRefGoogle Scholar
  8. Booysen FLR, Van Rensburg HCJ, Bachmann M, Louwagie G, Fairall L. (2007). Soc Indic Res. 81: 283–329.CrossRefGoogle Scholar
  9. Boulle A, Kenyon C, Skordis J, Wood R. (2002). S Afr Med J. 92: 811–817.PubMedGoogle Scholar
  10. Cleary SM, McIntyre D, Boulle AM. (2006). Cost Eff Resour Alloc. 4: 20.PubMedCrossRefGoogle Scholar
  11. Deghaye N, Painski RA, Desmond C. (2006). S Afr Med J 96: 140–143.PubMedGoogle Scholar
  12. Dolan P, Gudex C, Kind P, Williams A. (1996). Health Econ. 5: 141–154.PubMedCrossRefGoogle Scholar
  13. Dolan P (1997). Med Care. 35: 1095–1108.PubMedCrossRefGoogle Scholar
  14. Holmes WC, Shea JA. (1997). Qual Life Res. 6: 561–571.PubMedCrossRefGoogle Scholar
  15. Hughes J, Jelsma J, Maclean E, Darder M, Tinise X. (2004). Disabil Rehabil. 26: 371–376.PubMedCrossRefGoogle Scholar
  16. Jelsma J, Chivaura V, De Weerdt W, De Cock P. (2000). S Afr J Physiol. 56: 3–9.Google Scholar
  17. Jelsma J, Hansen K, de Weerdt W, de Cock P, Kind P. (2003) BMC Popul Health Metric. 1: 11.CrossRefGoogle Scholar
  18. Jelsma J, Maclean E, Hughes J, Tinise X, Darder M. (2005). AIDS Care. 17: 579–588.PubMedGoogle Scholar
  19. Jelsma J, Mhundwa K, De Weerdt W, De Cock P, Chimera J, Chivaura V. (2001). Cent Afr J Med. 47: 8–13.PubMedGoogle Scholar
  20. Jelsma J, Mkoka S, Amosun L, Nieuwveldt J. (2004). Disabil Rehabil. 26: 103–108.PubMedCrossRefGoogle Scholar
  21. Louwagie G, Bachmann MO, Meyer K, Booysen FLR, Fairall LR, Heunis C. (2007). BMC Publ Health. 7: 244.CrossRefGoogle Scholar
  22. Marseille E, Kahn JG, Billinghurst K, Saba J. (2001). Soc Sci Med. 52: 135–148.PubMedCrossRefGoogle Scholar
  23. Moller V, Schlemmer L. (1983). Soc Indic Res. 12: 225–279.CrossRefGoogle Scholar
  24. O’Keefe EA, Wood R. (1996). Qual Life Res. 5: 275–280.PubMedCrossRefGoogle Scholar
  25. Olweny CLM, Borok M, Gudza I, Clinch J, Cheang M, Kiire CF, Levy L, Otim-Oyet D, Nyamasve J, Schipper H. (2004). Int J Cancer. 113: 632–639.CrossRefGoogle Scholar
  26. Phaladze NA, Human S, Dlamini SB, Hulela EQ, Hadebe IM, Sukati NA, Makoae LN, Seboni NM, Moleko M, Holsemer L. (2005). J Nurs Scholarship. 37: 120–126.CrossRefGoogle Scholar
  27. Rosen S, Vincent JR, MacLeod W, Fox M, Thea DM, Simon JL. (2004). AIDS. 18: 317–324.PubMedCrossRefGoogle Scholar
  28. Sebit MB, Chandiwana SK, Latif AS, Gomo E, Acuda SW, Makoni F, Vushe J. (2000). Cent Afr J Med. 46: 208–213.PubMedGoogle Scholar
  29. Soorapanth S, Sansom S, Bulterys M, Besser M. Theron G, Fowler MG. (2006). J Acquir Immune Defic Syndr. 42: 213–221.Google Scholar
  30. Sweat MD, O’Reilly KR, Schmid GP, Denison J, Zoysa ID. (2004). AIDS. 18: 1661–1671.PubMedCrossRefGoogle Scholar
  31. WHOQOL Group. (1995). Soc Sci Med. 41: 1403–1409.CrossRefGoogle Scholar
  32. Wilkinson D, Floyd K, Gilks CF. (1998). AIDS. 12: 1675–1682.PubMedCrossRefGoogle Scholar
  33. Wilkinson D, Floyd K, Gilks CF. (2000). S Afr Med J. 90: 794–798.PubMedGoogle Scholar
  34. Wouters E, Meulemans H, Van Rensburg HCJ, Heunix JC, Mortelmans D. (2007). Qual Life Res. 16: 1461–1471.PubMedCrossRefGoogle Scholar
  35. UNAIDS. AIDS Epidemic Update. (2007). http://www.unaids.org/en/

Copyright information

© Springer Science+Business Media LLC 2010

Authors and Affiliations

  • M. O. Bachmann
  • G. Louwagie
  • L. R. Fairall

There are no affiliations available

Personalised recommendations