Chronic Obstructive Pulmonary Disease, Lung Function and Quality of Life in Adult Chinese

  • G. Xie
  • A. Paice
  • Y. Wu
Reference work entry


Chronic Obstructive Pulmonary Disease (COPD) is a common disease with 3–8% of prevalence in China. The risk factors of COPD include tobacco smoking, airway hyper-responsiveness, alpha-1 anti-trypsin inactivity, a rural habitat, increased age, reduced body mass index, reduced education level, poor living conditions, poor ventilation in the kitchen, occupational dust or biomass fuels, pulmonary problems in childhood, and a family history of pulmonary diseases. Quality of life (QOL) is attached importance in much of the world including China. Several measures of this, including the Chinese Quality of Life Measurement Form – 35 (Chinese QOL-35), have been developed. These measures have been used to explore the disease burden from COPD. Quality of life is lower in patients with COPD than healthy people. Lower pulmonary function predicts a lower future QOL independent of age, sex, height, and smoking status and is largely mediated through the development of chronic respiratory symptoms. QOL can be improved by factors such as smoking cessation, physical exercise and pulmonary rehabilitation. However, evidence for these interventions in the Chinese clinical environment is still lacking.


Chronic Obstructive Pulmonary Disease Smoking Cessation Chronic Obstructive Pulmonary Disease Patient Pulmonary Rehabilitation Reduce Body Mass Index 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

List of Abbreviations:


airway hyperresponsiveness


chronic obstructive pulmonary disease

Chinese QOL-35

Chinese quality of life measurement form – 35 items


forced expiratory volume in the 1st second


percentage of FEV1 divided by FEV1 predicted by age, sex, and height


forced vital capacity


inspiratory capacity


provocative concentration of methacholine required to reduce FEVl by 20%


quality of life


residual volume


36-item medical outcome study short form health status survey


St George's respiratory questionnaire


total lung capacity


  1. Anthonisen NR, Connett JE, Kiley JP, et al. (1994). JAMA. 272: 1497–1505.PubMedCrossRefGoogle Scholar
  2. Boueri FM, Bucher-Bartelson BL, Glenn KA, et al. (2001). Chest. 119: 77–84.PubMedCrossRefGoogle Scholar
  3. Campbell VA, Crews JE, Moriarty DG, Zack MM, Blackman DK. (1999). MMWR CDC Surveill Summ. 48(8): 131–156.PubMedGoogle Scholar
  4. Cheng X, Li J, Zhang Z, et al. (1998). Chin J Tuberc Respir Dis. 21(12): 749–752.Google Scholar
  5. Cheng X, Wu Y, Li J, et al. (1999). Chin J Tuberc Respir Dis. 22(10): 602–604.Google Scholar
  6. Domingo-Salvany A, Lamarca R, Ferrer M, et al. (2002). Am J Respir Crit Care Med. 166: 680–685.PubMedCrossRefGoogle Scholar
  7. Engström CP, Persson LO, Larsson S, et al. (1996). Thorax. 51: 825–830.PubMedCrossRefGoogle Scholar
  8. Fang J. (2000). The Assessment and Application of Quality of Life. Publishing House of Beijing Medical University, Beijing.Google Scholar
  9. Fayers PM, Machin D. (2000). Quality of life: assessment, analysis and interpretation, 1st ed. Wiley & Sons, Chichester NY.Google Scholar
  10. Hopman WM, Towheed T, Anastassiades T, Tenenhouse A, Poliquin S, Berger C, Joseph L, Brown JP, Murray TM, Adachi JD, Hanley DA, Papadimitropoulos E. (2000). CMAJ. 163(3): 265–71.PubMedGoogle Scholar
  11. Huang X, Xie C. (2006). Chin J Tuberc Respir Dis. 29(5): 350–351.Google Scholar
  12. Jin P. (1992). J Psychosom Res. 36: 361–370.PubMedCrossRefGoogle Scholar
  13. Lanuza DM, Lefaiver C, Cabe MM, Farcas GA, Garrity E. (2000). Chest. 118: 115–122.PubMedCrossRefGoogle Scholar
  14. Lee LYK, Lee DTF, Woo J. (2007). J Clin Nurs. 16(8): 1580–1582.PubMedCrossRefGoogle Scholar
  15. Lenfant C, Khaltaev N, et al. (2001). Global Initiative for chronic obstructive lung disease (GOLD). Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease NHLBI/WHO Workshop Report. National Institutes of Health, National Heart, Lung, and Blood Institute World Health Organization. pp. 4–6.Google Scholar
  16. Leung AS, Chan KK, Sykes K, Chan KS. (2006). Chest. 130(1): 119–125.PubMedCrossRefGoogle Scholar
  17. Li L, Wang HM, Shen Y. (2003). J Epidemiol Commun Health. 57(4): 259–263.CrossRefGoogle Scholar
  18. Maa SH, Gauthier D, Turner M. (1997). J Cardiopulm Rehabil. 17(4): 268–276.PubMedCrossRefGoogle Scholar
  19. Maxwell CJ, Hirdes JP. (1993). Am J Prev Med. 9: 338–345.PubMedGoogle Scholar
  20. Ministry of Health of the People's Republic of China. (2004). China Health Statistical Yearbook, Vol. 10. Peiking Union Medical College Publishing House, Beijing, pp. 221–276.Google Scholar
  21. Nagatomo I, Nomaguchi M, Matsumoto K. (1994). Jpn J Psychiatry Neurol. 48(3): 511–515.PubMedGoogle Scholar
  22. Prigatano GP, Wright EC, Levin D. (1984). Arch Intern Med. 144: 1613–1619.PubMedCrossRefGoogle Scholar
  23. Spencer S, Calverley PMA, Burge PS, et al. (2001). Am J Respir Crit Care Med. 163: 122–128.PubMedGoogle Scholar
  24. Ware JE, Shebourne CD. (1992). Med Care. 30(6): 473–483.PubMedCrossRefGoogle Scholar
  25. WHOQOL Group. (1998). Soc Sci Med. 46(12): 1569–1585.Google Scholar
  26. Wijkstra PJ, Van Altena R, Kraan J, Otten V, Postma DS, Koeter GH. (1994). Eur Respir J. 7: 269–273.PubMedCrossRefGoogle Scholar
  27. Wijnhoven HAH, Kriegsman DMW, Hesselink AE, et al. (2001). Chest. 119: 1034–1042.PubMedCrossRefGoogle Scholar
  28. Wong KW, Wong FK, Chan MF. (2005). J Adv Nurs. 49(2): 210–222.PubMedCrossRefGoogle Scholar
  29. Woolf SH, Rothemich SF, Johnson RE, Marsland DW. (1999). Am J Prev Med. 17(2): 134–137.PubMedCrossRefGoogle Scholar
  30. Wu Y, Xie G, Li Y, Zhou B, Zhang P, Shi P, Ren F, Ma L. (2005). Chin J Epidemiol. 26(10): 751–756.Google Scholar
  31. Wu YF, Xie G, Li Y, Zhou BF, Zhang PH, Ren FX, Shi P, Ma LY. (2005). Zhonghua Liu Xing Bing Xue Za Zhi. 26(10): 751–756.PubMedGoogle Scholar
  32. Xie G. (2003). The Development of Chinese General Quality of Life Instrument and the Relationship between Baseline Pulmonary Function and Quality of Life Nine Years Later. Peiking Union Medical College, Beijing, pp. 109.Google Scholar
  33. Xie G, Cheng X, Li Q, et al. (2005). Mol Cardiol China. 5(5): 713–716.Google Scholar
  34. Xie G, Cheng X, Xu X, et al. (2001). Natl Med J china. 81(22): 1356–1359.Google Scholar
  35. Xie G, Cheng X, Xu X, et al. (2005). Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 27(1): 92–98.PubMedGoogle Scholar
  36. Xie G, Li Y, Shi P, Zhou B, Zhang P, Wu Y. (2005). Chest. 128: 2448–2457.PubMedCrossRefGoogle Scholar
  37. Xie G, Li Y, Zhou B, et al. (2005). Multicenter Study Cardiovasc Epidemiol Prevention Control. 1(1): 107–108.Google Scholar
  38. Xie G, Li Y, Zhou B, Zhang P, Shi P, Ren F, Ma L, Wu Y. (2006). Chin J Chonic Dis. 5(1): 1–7.CrossRefGoogle Scholar
  39. Yang G, Fan L, Tan J, et al. (1999). JAMA. 282: 1247–1253.PubMedCrossRefGoogle Scholar
  40. Yang G, Ma J, Chen AP, Brown S, Taylor CE, Samet JM. (2004). Int J Epidemiol. 33(5): 1103–1110.PubMedCrossRefGoogle Scholar
  41. Zhang G, Jin X, Zhang P. (2006). Chin J Postgrad Med. 29: 30–33.Google Scholar
  42. Zhong N, Wang C, Yao W, Chen P, Kang J, Huang S, Chen B, Wang C, Ni D, Zhou Y, Liu S, Wang X, Wang D, Lu J, Zheng J, Ran P. (2007). Am J Respir Crit Care Med. 176(8): 753–760.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media LLC 2010

Authors and Affiliations

  • G. Xie
  • A. Paice
  • Y. Wu

There are no affiliations available

Personalised recommendations