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Table 167-2 Commonly-used and validated measures of QOL after radical prostatectomy

From: Quality of Life in Men Undergoing Radical Prostatectomy for Prostate Cancer

1. The UCLA Prostate Cancer Index (UCLA PCI): 20-item instrument that is prostate-specific in nature. Does not contain questions regarding general HRQOL, and therefore commonly administered along with general health instrument (e.g., RAND SF-36).

2. The Expanded Prostate Cancer Index-Composite (EPIC): Expanded version of the UCLA PCI with 30 additional disease-specific items to more comprehensively define QOL outcomes following prostate cancer treatment. The EPIC includes additional 8 disease specific domains.

3. The European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire with its prostate cancer specific module (EORTC QLQ-C30): Broad-based questionnaire was originally designed to measure cancer-specific QOL outcomes with various types of malignancies. Includes five general scales, a global health scale, three symptom scales, and 6 additional items. A prostate cancer module of 20 additional questions regarding bowel, urinary, and sexual function was added.

4. The Functional Assessment of Cancer Therapy-Prostate Instrument (FACT-P): Questionnaire containing 38 items; 26 measure five general QOL domains with the remaining 12 measuring disease-specific issues. Perhaps better suited to assessing men with metastatic disease.