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Handbook of Disease Burdens and Quality of Life Measures pp 2615–2631Cite as

Low Testosterone Level in Men and Quality of Life

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Abstract:

The concept of age-related androgen deficiency in men, also termed late-onset hypogonadism (LOH), has opened up public awareness about men's health issues. Low testosterone levels can lead to depressed mood, sexual dysfunction, cognitive impairment, osteoporosis, cardiovascular disease, and metabolic syndrome. Low testosterone levels also affect health-related quality of life (QOL), impacting physical, social, emotional, cognitive, and sexual functioning. Use of generic questionnaires such as the Short-Form 36-Item Health Survey likely underestimates the impact of low testosterone levels on QOL. Other QOL scales that assess cognitive impact, sexual functioning, or body appearance need to be considered when assessing men with low testosterone levels. The Aging Males’ Symptoms scale is the most frequently used scale to measure health-related QOL in aging males. Evidence points toward a high reliability and high validity of this scale to measure and to compare HRQOL of aging males.

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Abbreviations

ACTH:

adrenocorticotropine hormone

AMS:

aging males’ symptoms

DHEA:

dehydroepiandrosterone

DHT:

dihydrotestosterone

FSH:

follicle-stimulating hormone

GnRH:

gonadotropin-releasing hormone

HRQOL:

health-related quality of life

HSQ:

Health Status Questionnaire

LF:

luteinizing hormone

LOH:

late-onset hypogonadism

QOL:

quality of life

SF-12:

Short-Form 12-Item Health Survey

SF-36:

Short-Form 36-Item Health Survey

SHBG:

sex hormone binding globulin

T:

testosterone

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Authors and Affiliations

  1. Department of Urology, Teikyo University School of Medicine, Tokyo, Japan

    S. Horie

Authors
  1. S. Horie
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Editor information

Editors and Affiliations

  1. Dept. Nutrition and Dietetics Nutritional Sciences Research Division School of Biomedical & Health Sciences, King's College London, Franklin‐Wilkins Building 150 Stamford Street, SE1 9NH, London, UK

    Victor R. Preedy (Prof.) (Prof.)

  2. Mel and Enid Zuckerman College of Public Health, University of Arizona, Health Science Center 1295 N. Martin, P.O. Box 245155, 85724-5155, Tucson, AZ

    Ronald R. Watson (Prof.) (Prof.)

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Horie, S. (2010). Low Testosterone Level in Men and Quality of Life. In: Preedy, V.R., Watson, R.R. (eds) Handbook of Disease Burdens and Quality of Life Measures. Springer, New York, NY. https://doi.org/10.1007/978-0-387-78665-0_152

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  • DOI: https://doi.org/10.1007/978-0-387-78665-0_152

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-78664-3

  • Online ISBN: 978-0-387-78665-0

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