Intrauterine Growth Restriction and Later Quality of Life

  • D. Spence
Reference work entry


 Intrauterine growth restriction (IUGR) remains a major clinical problem in modern obstetrics. While technology has yet to aid significant prevention of IUGR, the past few decades has seen the introduction of some of the most innovative therapies in the history of  neonatal intensive care. This has resulted in an increased survival rate of a heterogeneous group of babies, including those with intrauterine growth restriction. It is therefore important to assess if the associated problems with these babies, impact on health related  quality of life long-term. Subtle psychological and social differences have been reported in childhood and early adult life and higher incidence of coronary heart disease, high blood pressure, and diabetes have also been reported in later life. However, it is unclear how this impacts on overall quality of life. Quality of life is considered an important outcome measure for healthcare interventions in adults and health status measures are key determinants of health service use. Despite the extensive cohort studies undertaken to date, there is a dearth of literature on the relationship between IUGR and quality of life, particularly in later life. A recent study addressed this gap in the literature, comparing subjects born with IUGR and a control group with normal birth weight for  gestation. Quality of life in adulthood was assessed using the Short Form-36 health survey (SF-36). The two groups reported similar quality of life on each of the eight dimensions of the SF-36 and there were no significant differences between them. Adjusting for potential confounding variables did not alter this conclusion. This chapter summarizes the impact of IUGR on later quality of life.


Fetal Growth Fetal Alcohol Syndrome Intrauterine Growth Restriction Health Status Measure Normal Birth Weight 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

List of Abbreviations:


Appropriate for gestational age


Confidence intervals






General Practitioner


Intrauterine growth restriction


Last menstrual period


Standard deviation


Short Form 36 health survey


Small for gestational age


Statistical package for social sciences


United Kingdom


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Copyright information

© Springer Science+Business Media LLC 2010

Authors and Affiliations

  • D. Spence
    • 1
  1. 1.Nursing and Midwifery Research UnitQueen’s University BelfastBelfastUK

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