Table 131-2 Generic and disease-specific instruments used in different studies evaluating quality of life in liver cirrhosis

Generic instruments

Assessment of health-related quality of life

 The 36-item short-form health survey (SF-36) (Hauser et al., 2004a; Marchesini et al., 2001; Younossi et al., 2001b)

 Nottingham health profile (NHP) (Bianchi et al., 2003; Marchesini et al., 2001)

 Sickness impact profile (SIP) (Groeneweg et al., 1998; Prasad et al., 2007; Tarter et al., 1992)

 Austin quality of life scale (AUSQUAL) (Moore et al., 2000)

 Quality of life index (Gulberg et al., 2002)

Assessment of mental health

 Brief symptom inventory (BSI) (De Bona et al., 2000)

 Beck Depression Inventory (BDI) (Bianchi et al., 2005; Singh et al., 1997)

 Hospital anxiety and depression (HAD) (Hauser et al., 2004a)

 Psychological general well-being index (PGWBI) (Bianchi et al., 2005)

Assessment of gastrointestinal symptoms

 Gastrointestinal symptom rating scale (GSRS) (Kalaitzakis et al., 2006)

Assessment of fatigue

 Multidimensional fatigue index-20 (MFI-20) (van der Plas et al., 2003)

Assessment of sexual function

 International index of erectile function (Toda et al., 2005)

Liver disease-specific instruments

 Chronic liver disease questionnaire (CLDQ) (Younossi et al., 1999)

 Liver disease quality of life instrument in chronic liver disease (LDQOL) (Gralnek et al., 2000)

 Liver disease symptom index (LDSI) (van der Plas et al., 2004)

 Chronic liver disease quality of life (CLD-QOL) questionnaire (Lee et al., 2008)