Advertisement

Health-Related Quality of Life of Living Kidney Donors

  • Ja Hyeon Ku
  • Hyeon Hoe Kim
Reference work entry

Abstract:

Kidney transplantation provides improvement in both the length and quality of life (QOL) in patients receiving dialysis. The kidneys used for transplantation are currently obtained from either cadavers or living donors. However, the demand for cadaver organs far exceeds the supply. The shortage of organs and the steadily growing waiting time for a cadaver kidney transplantation have forced the medical community to look for alternatives, such as living kidney donation. Because of the better outcome with the living grafts for the recipients compared to the cadaver transplants, living donor programs have been expanding. The benefits of living donor transplantation have been well documented. In addition, patients have an extensive medical work-up that not infrequently identifies occult medical problems, a boost in self-esteem and an increased sense of well-being. Furthermore, living kidney donation has not been shown to have a detrimental effect on the physical or psychological well-being of donors. However, available data examining the health-related QOL issues of living donors are currently limited. Although there is no consensus on the “gold standard” instrument to measure QOL in this population, to date, the SF-36 has been widely used to measure the QOL of living kidney donors. Most studies have suggested that living kidney donors have similar or higher scores on the QOL questionnaires compared with the healthy general population. The evolution of surgical techniques used for transplantation including the mini-incision and laparoscopy has made living kidney donation a more attractive option for patients and their potential donors. In addition, several variables have been proposed as an influencing the QOL of living kidney donors but these factors are not conclusive. Careful donor selection, with appropriate pre-transplantation psychiatric consulting as well as regular post-donation psychosocial screening and the provision of specific interventions to those in need are recommended for a successful living kidney donor program.

Keywords

Physical Component Summary Mental Component Summary Kidney Donor Donor Nephrectomy Live Kidney Donor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

List of Abbreviations:

MCS

mental component summary

PCS

physical component summary

QOL

quality of life

SF-36

short-form 36

References

  1. Aguiar WF, Passerotti CC, Claro JF, Almeida CJ, Gattas N, Cedenho AP, Pestana JO, Ortiz V. (2007). Clin Transplant. 21: 269–276.PubMedCrossRefGoogle Scholar
  2. Bargman V, Sundaram CP, Bernie J, Goggins W. (2006). J Endourol. 20: 717–722.PubMedCrossRefGoogle Scholar
  3. Bergman S, Feldman LS, Mayo NE, Carli F, Anidjar M, Klassen DR, Andrew CG, Vassiliou MC, Stanbridge DD, Fried GM. (2005). Am J Transplant. 5: 2489–2495.PubMedCrossRefGoogle Scholar
  4. Bruzzone P, Pretagostini R, Poli L, Rossi M, Berloco PB. (2005). Transplant Proc. 37: 2436–2438.PubMedCrossRefGoogle Scholar
  5. Buell JF, Lee L, Martin JE, Dake NA, Cavanaugh TM, Hanaway MJ, Weiskittel P, Munda R, Alexander JW, Cardi M, Peddi VR, Zavala EY, Berilla E, Clippard M, First MR, Woodle ES. (2005). Clin Transplant. 19: 102–109.PubMedCrossRefGoogle Scholar
  6. Bullinger M, Alonso J, Apolone G, Leplege A, Sullivan M, Wood-Dauphinee S, Gandek B, Wagner A, Aaronson N, Bech P, Fukuhara S, Kaasa S, Ware JE. Jr. (1998). J Clin Epidemiol. 51: 913–923.PubMedCrossRefGoogle Scholar
  7. Cabrer C, Oppenhaimer F, Manyalich M, Paredes D, Navarro A, Trias E, Lacy A, Rodriguez-Villar C, Vilarrodona A, Ruiz A, Gutierrez R. (2003). Transplant Proc. 35: 1631–1632.PubMedCrossRefGoogle Scholar
  8. Carli F, Mayo N. (2001). Br J Anaest. 87: 531–533.CrossRefGoogle Scholar
  9. Chen CH, Chen Y, Chiang YJ, Wu CT, Chen HW, Chu SH. (2004). Transplant Proc. 36: 1920–1921.PubMedCrossRefGoogle Scholar
  10. Dahm F, Weber M, Muller B, Pradel FG, Laube GF, Neuhaus TJ, Cao C, Wuthrich RP, Thiel GT, Clavien PA. (2006). Nephrol Dial Transplant. 21: 2563–2568.PubMedCrossRefGoogle Scholar
  11. de Graaf Olson W, Bogetti-Dumlao A. (2001). Prog Transplant. 11: 108–115.PubMedGoogle Scholar
  12. Fehrman-Ekholm I, Brink B, Ericsson C, Elinder CG, Duner F, Lundgren G. (2000). Transplantation. 69: 2067–2071.PubMedCrossRefGoogle Scholar
  13. Giessing M, Reuter S, Deger S, Tullmann M, Hirte I, Budde K, Fritsche L, Slowinski T, Dragun D, Neumayer HH, Loening SA, Schonberger B. (2005). Transplant Proc. 37: 2011–2015.PubMedCrossRefGoogle Scholar
  14. Giessing M, Reuter S, Schonberger B, Deger S, Tuerk I, Hirte I, Budde K, Fritsche L, Morgera S, Neumayer HH, Loening SA. (2004). Transplantation. 78: 864–872.PubMedCrossRefGoogle Scholar
  15. Hirvas J, Enckell M, Kuhlback B. (1980). Acta Med Scand. 208: 285–287.PubMedCrossRefGoogle Scholar
  16. Isotani S, Fujisawa M, Ichikawa Y, Ishimura T, Matsumoto O, Hamami G, Arakawa S, Iijima K, Yoshikawa N, Nagano S, Kamidono S. (2002). Urology. 60: 588–592.PubMedCrossRefGoogle Scholar
  17. Jacobs C, Johnson E, Anderson K, Gillingham K, Matas A. (1998). Adv Ren Replace Ther. 5: 89–97.PubMedGoogle Scholar
  18. Jackobs S, Becker T, Luck R, Jager MD, Nasham B, Gwinner W, Schwarz A, Klempnauer J, Neipp M. (2005). World J Urol. 23: 343–348.PubMedCrossRefGoogle Scholar
  19. Johnson EM, Anderson JK, Jacobs C, Suh G, Humar A, Suhr BD, Kerr SR, Matas AJ. (1999). Tranaplantation. 67: 717–721.CrossRefGoogle Scholar
  20. Jordan J, Sann U, Janton A, Gossmann J, Kramer W, Kachel HG, Wilhelm A, Scheuermann E. (2004). J Nephrol. 17: 728–735.PubMedGoogle Scholar
  21. Kok NF, Lind MY, Hansson BM, Pilzecker D, Mertens zur Borg IR, Knipscheer BC, Hazebroek EJ, Dooper IM, Weimar W, Hop WC, Adang EM, van der Wilt GJ, Bonjer HJ, van der Vilet JA, IJzermans JN. (2006). Br Med J. 333: 221–224.Google Scholar
  22. Kuo PC, Johnson LB. (2000). Transplantation. 69: 2211–2213.PubMedCrossRefGoogle Scholar
  23. Lima DX, Petroianu A, Hauter HL. (2006). Quality of life and surgical complications of kidney donors in the late post-operative period in Brazil. Nephrol Dial Transplant. 21: 3238–3242.PubMedCrossRefGoogle Scholar
  24. Lindstrom P, Haggman M, Wadstrom J. (2002). Hand-assisted laparoscopic surgery (HALS) for live donor nephrectomy is more timeand cost-effective than standard laparoscopic nephrectomy. Surg Endosc. 16: 422–425.PubMedCrossRefGoogle Scholar
  25. Lumsdaine JA, Wray A, Power MJ, Jamieson NV, Akyol M, Andrew Bradley J, Forsythe JL, Wigmore SJ. (2005). Transpl Int. 18: 975–980.PubMedCrossRefGoogle Scholar
  26. Najarian JS. (2005). Transplant Proc. 37: 3592–3594.PubMedCrossRefGoogle Scholar
  27. Neipp M, Jackobs S, Becker T, zu Vilsendorf AM, Winny M, Lueck R, Klempnauer J, Nashan B. (2004). Transplantation 78: 1356–1361.PubMedCrossRefGoogle Scholar
  28. Ozcurumez G, Tanriverdi N, Colak T, Emiroglu R, Zileli L, Haberal M. (2004). Transplant. Proc. 36: 114–116.PubMedCrossRefGoogle Scholar
  29. Pace KT, Dyer SJ, Stewart RJ, Honey RJ, Poulin EC, Schlachta CM, Mamazza J. (2003). Surg Endosc. 17: 143–152.PubMedCrossRefGoogle Scholar
  30. Perry KT, Freedland SJ, Hu JC, Phelan MW, Kristo B, Gritsch AH, Rajfer J, Schulam PG. (2003). J Urol. 169: 2018–2021.PubMedCrossRefGoogle Scholar
  31. Reimer J, Rensing A, Haasen C, Philipp T, Pietruck F, Franke GH. (2006). Transplantation 81: 1268–1273.PubMedCrossRefGoogle Scholar
  32. Rodrigue JR, Cross NJ, Newman RC, Widows MR, Guenther RT, Kaplan B, Morgan MA, Howard RJ. (2006). Prog Transplant. 16: 162–169.PubMedGoogle Scholar
  33. Ruiz-Deya G, Cheng S, Palmer E, Thomas R, Slakey D. (2001). J Urol. 166: 1270–1273.PubMedCrossRefGoogle Scholar
  34. Schnitzbauer AA, Hornung M, Seidel U, Kruger B, Kramer BK, Schlitt HJ, Obed A. (2007). Clin Transplant. 21: 235–240.PubMedCrossRefGoogle Scholar
  35. Schover LR, Streem SB, Boparai N, Duriak K, Novick AC. (1997). J Urol. 157: 1596–1601.PubMedCrossRefGoogle Scholar
  36. Schweitzer EJ, Wilson J, Jacobs S, Machan CH, Philosophe B, Farney A, Colonna J, Jarrell BE, Barlett ST. (2000). Ann Surg. 232: 392–400.PubMedCrossRefGoogle Scholar
  37. Simforoosh N, Basiri A, Tabibi A, Shakhssalim N, Hosseini Moghaddam SM. (2005). BJU Int. 95: 851–855.PubMedCrossRefGoogle Scholar
  38. Smith GC, Trauer T, Kerr PG, Chadban SJ. (2003). Transplantation. 76: 807–809.PubMedCrossRefGoogle Scholar
  39. Smith GC, Trauer T, Kerr PG, Chadban SJ. (2004). Transplantation. 78: 1384–1389.PubMedCrossRefGoogle Scholar
  40. Taghavi R, Mahdavi R, Toufani H. (2001). Transplant Proc. 33: 2636–2637.PubMedCrossRefGoogle Scholar
  41. Tanriverdi N, Ozcurumez G, Colak T, Duru C, Emiroglu R, Zileli L, Haberal M. (2004). Transplant Proc. 36: 117–119.PubMedCrossRefGoogle Scholar
  42. Toronyi E, Alfoldy F, Jaray J, Remport A, Mathe Z, Szabo J, Gati Z, Perner F. (1998). Transplant Int. 11(Suppl 1): S481–S483.CrossRefGoogle Scholar
  43. Troppmann C, Johnston WK. 3rd, Pierce JL, McVicar JP, Perez RV. (2006). Pediatr Nephrol. 21: 1052–1054.PubMedCrossRefGoogle Scholar
  44. Vastag B. (2003). J Am Med Assoc. 290: 181–182.CrossRefGoogle Scholar
  45. Velidedeoglu E, Williams N, Brayman KL, Desai NM, Campos L, Palanjian M, Wockik M, Bloom R, Grossman RA, Mange K, Barker CF, Naji A, Markmann JF. (2002). Transplantation. 74: 169–172.PubMedCrossRefGoogle Scholar
  46. Virzi A, Signorelli MS, Veroux M, Giammarresi G, Maugeri S, Nicoletti A, Veroux P. (2007). Transplant Proc. 39: 1791–1793.PubMedCrossRefGoogle Scholar
  47. Vlaovic PD, Devins GM, Abbey S, Wright E, Robinette MA. (1999). Can J Urol. 6: 859–864.PubMedGoogle Scholar
  48. Weizer N, Weizman A, Shapira Z, Yussim A, Munitz H. (1989). Psychother Psychosomat. 51: 216–219.CrossRefGoogle Scholar
  49. Westlie L, Fauchald P, Talseth T, Jakobsen A, Flatmark A. (1993). Nephrol Dial Transplant. 8: 1146–1150.PubMedGoogle Scholar
  50. Zargooshi J. (2001). J Urol. 166: 1790–1799.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media LLC 2010

Authors and Affiliations

  • Ja Hyeon Ku
  • Hyeon Hoe Kim

There are no affiliations available

Personalised recommendations