Sporadic Pancreatic Endocrine Tumors

  • Volker Fendrich
  • Peter Langer
  • Detlef K. Bartsch
Reference work entry


Pancreatic endocrine tumors (PETs) are uncommon but fascinating tumors with an annual incidence of 1 per 100,000 people. PETs present as either functional tumors, causing specific hormonal syndromes like Zollinger-Ellison-Syndrome (ZES) or organic hyperinsulinism, or as non-functional pancreatic tumors (NFPTs). The natural history of PETs is highly variable. Small, benign neoplasms such as 90% of all insulinomas are readily curable by surgical resection. Most other functional and malignant NFPTs have a less favorable chance for cure. Patients with completely resected tumors generally have a good prognosis, and an aggressive surgical approach combined with conservative treatment options in patients with advanced disease often results in long-term survival.


Liver Metastasis Orthotopic Liver Transplantation Islet Cell Tumor Duodenal Tumor Duodenal Gastrinomas 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Volker Fendrich
    • 1
  • Peter Langer
    • 1
  • Detlef K. Bartsch
    • 1
  1. 1.Department of SurgeryUniversity Hospital Marburg and GiessenMarburgGermany

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