Diagnostic and Therapeutic Endoscopy in Pancreatic Cancer

  • Folasade P. May
  • Field F. Willingham
  • David L. Carr-Locke
Reference work entry


While endoscopic ultrasound is the most sensitive procedure for the diagnosis of pancreatic cancer, endoscopic retrograde cholangiopancreatography (ERCP) is a safe and effective approach to the diagnosis, treatment, and palliation of biliary and pancreatic disorders [1]. Most patients with pancreatic cancer will have multiple contacts with the therapeutic endoscopy service over the course of their disease. ERCP is commonly employed to examine the biliary tree and pancreatic duct, to confirm the presence of obstructive lesions, and to define the location of benign and malignant strictures. The procedure allows for tissue diagnosis in some settings via sampling of ductal strictures. There is a major role for ERCP in the palliation of pancreatic cancer where stent placement can relieve obstructive jaundice and enteral stenosis. This chapter addresses the use of ERCP in pancreatic adenocarcinoma with respect to cancer diagnosis, therapy, and palliation.


Pancreatic Cancer Pancreatic Duct Stent Placement Metallic Stents Gastric Outlet Obstruction 


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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Folasade P. May
    • 1
    • 3
  • Field F. Willingham
    • 1
    • 2
    • 3
  • David L. Carr-Locke
    • 1
    • 3
  1. 1.Department of Medicine, Gastrointestinal Unit, Massachusetts General HospitalHarvard Medical SchoolBostonUSA
  2. 2.Department of Medicine, Division of Gastroenterology, Brigham and Women’s HospitalHarvard Medical SchoolBostonUSA
  3. 3.Director of the Endoscopy Institute, Brigham and Women’s HospitalDivision of GastroenterologyBostonUSA

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