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The Genus Helicobacter

  • Reference work entry
The Prokaryotes

Historical Background

Spiral-shaped bacteria were first seen in human gastric mucosa early in the twentieth century (Krienitz, 1906) and were subsequently described by several investigators (reviewed in Marshall, 1989). Similar organisms were also seen in the gastric mucosa of dogs, cats and a variety of other animals (Rappin, 1881; Bizzozero, 1892; Salomon, 1896; Lim, 1920; Doenges, 1939). The significance of these organisms was alternately debated and forgotten until Marshall and Warren isolated a Gram-negative, microaerophilic bacterium from human gastric biopsies and proposed that the organism may be the cause of chronic gastritis and peptic ulcer disease (Marshall and Warren, 1984a). The bacterium was thought originally to be a member of the genus Campylobacter and named “Campylobacter pyloridis,” later corrected to “Campylobacter pylori.” Subsequent 16S rRNA sequence analysis showed that the distance between the true campylobacters and C. pyloriwas sufficient to exclude it from...

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Authors
  1. Jay V. Solnick
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  2. Jani L. O’rourke
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  3. Peter Vandamme
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  4. Adrian Lee
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Editor information

Editors and Affiliations

  1. Department of Microbiology, University of Minnesota, Box 196, Twin Cities, Minneapolis, MN 55455-0312, USA

    Martin Dworkin Professor Dr. (Editor-in-Chief) (Editor-in-Chief)

  2. Department of Microbiology and Immunology, Stanford University Medical School, 299 Campus Drive, Fairchild, D039, Stanford, CA, 94305-5124, USA

    Stanley Falkow

  3. Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Ramat-Aviv, 69978, Israel

    Eugene Rosenberg

  4. Department of Microbiology, Technical University Munich, 80290, Munich, Germany

    Karl-Heinz Schleifer

  5. DSMZ- German Collection of Microorganisms and Cell Cultures GmbH, Mascheroder Weg 1b, 38124, Braunschweig, Germany

    Erko Stackebrandt

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Solnick, J.V., O’rourke, J.L., Vandamme, P., Lee, A. (2006). The Genus Helicobacter . In: Dworkin, M., Falkow, S., Rosenberg, E., Schleifer, KH., Stackebrandt, E. (eds) The Prokaryotes. Springer, New York, NY. https://doi.org/10.1007/0-387-30747-8_5

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