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The Genus Burkholderia

  • Reference work entry
The Prokaryotes

Introduction

The genus Burkholderia contains organisms that are important causes of human, animal and plant disease, as well as organisms useful in promoting plant growth and bioremediation. The type species, Burkholderia cepacia, is important in all of these activities. Originally identified as a plant pathogen that caused soft rot in onions (Burkholder, 1950), B. cepacia has emerged in the last 20 years as an opportunistic pathogen in nosocomial infections, particularly in individuals with cystic fibrosis (CF) or chronic granulomatous disease (Gilligan, 1991; Govan et al., 1996b; LiPuma, 1998; Speert et al., 1994). Other significant human and animal pathogens include B. pseudomallei, the cause of melioidosis, and B. mallei, the cause of glanders (Sanford, 1995). A newly described nonpathogenic species, B. thailandensis (Brett et al., 1998), has been useful in defining the pathogenesis of diseases caused by B. pseudomallei and B. mallei (Brett et al., 1997).

Burkholderia cepaciais a...

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Literature Cited

  • Ashdown, L. R., and J. M. Koehler. 1990 Production of hemolysin and other extracellular enzymes by clinical isolates of Pseudomonas pseudomallei J. Clin. Microbiol. 28 2331–2334

    PubMed  CAS  Google Scholar 

  • Baird, R. M., H. Brown, A. W. Smith, and M. L. Watson. 1999 Burkholderia cepacia is resistant to the antimicrobial activity of airway epithelial cells Immunopharmacology 44(3) 267–272

    Article  PubMed  CAS  Google Scholar 

  • Batmanov, V. P. 1991 Sensitivity of Pseudomonas mallei to fluoroquinolones and their efficacy in experimental glanders Antibiot. Khimioter. 36 31–34

    PubMed  CAS  Google Scholar 

  • Bauernfeind, A., C. Roller, D. Meyer, R. Jungwirth, and I. Schneider. 1998 Molecular procedure for rapid detection of Burkholderia mallei and Burkholderia pseudomallei J Clin Microbiol. 36(9) 2737–2744

    PubMed  CAS  Google Scholar 

  • Bauernfeind, A., I. Schneider, R. Jungwirth, and C. Roller. 1999 Discrimination of Burkholderia multivorans and Burkholderia vietnamiensis from Burkholderia cepacia genomovars I, III and IV by PCR J. Clin. Microbiol. 37 1335–1339

    PubMed  CAS  Google Scholar 

  • Benenson, A. S. 1995 Control of Communicable Diseases manual American Public Health Association Washington DC 577

    Google Scholar 

  • Bharadwaj, R., A. Kagal, S. K. Deshpandy, S. A. Joshi, P. M. Khare, A. R. Junnakar, and M. A. Phadke. 1994 Outbreak of plague-like illness caused by Pseudomonas pseudomallei in Maharashtra, India Lancet 344 1574

    Article  PubMed  CAS  Google Scholar 

  • Brett, P. J., D. C. Mah, and D. E. Woods. 1994 Isolation and characterization of Pseudomonas pseudomallei flagellin proteins Infect. Immunol. 62 1914–1919

    CAS  Google Scholar 

  • Brett, P. J., D. DeShazer, and D. E. Woods. 1997 Characterization of Burkholderia pseudomallei and Burkholderia pseudomallei-like strains Epidemiol. Infect. 118 137–148

    Article  PubMed  CAS  Google Scholar 

  • Brett, P. J., D. DeShazer, and D. E. Woods. 1998 Burkholderia thailandensis sp. Nov., a Burkhoderia pseudomallei-like species Int. J. System. Bacteriol. 48 317–320

    Article  CAS  Google Scholar 

  • Bryan, L. E., S. Wong, D. E. Woods, D. A. B. Dance, and W. Chaowagul. 1994 Passive protection of diabetic rats with antisera specific for the polysaccharide portion of the lipopolysaccharide isolated from Pseudomonas pseudomallei Can. J. Infect. Dis. 5 170–178

    PubMed  CAS  Google Scholar 

  • Burkholder, W. H. 1950 Sour skin, a bacterial rot of onion bulbs Phytopathology 40 115–117

    Google Scholar 

  • Burns, J. L., M. Jonas, E. Y. Chi, D. K. Clark, A. Berger, and A. Griffith. 1996 Invasion of respiratory epithelial cells by Burkholderia (Pseudomonas) cepacia Infect. Immunol. 64(10) 4054–4059

    CAS  Google Scholar 

  • Chaowagul, W., N. J. White, D. A. B. Dance, Y. Wattanagoon, P. Naigowit, T. M. E. Davis, S. Looareesuwan, and N. Pitawatchara. 1989 Melioidosis, a major cause of community-acquired septicemia in northeastern Thailand J. Infect. Dis. 159 890–899

    Article  PubMed  CAS  Google Scholar 

  • Corey, M., and V. Farewell. 1996 Determinants of mortality from cystic fibrosis in Canada, 1970–1989 Am. J. Epidemiol. 143(10) 1007–1017

    Article  PubMed  CAS  Google Scholar 

  • Crosa, J. H. 1989 Genetics and molecular biology of siderophore-mediated iron transport in bacteria Microbiol. Rev. 53(4) 517–530

    PubMed  CAS  Google Scholar 

  • Dance, D. A., V. Wuthiekanun, N. J. White, and W. Chaowagul. 1988 Antibiotic resistance in Pseudomonas pseudomallei Lancet 1 994–995

    Article  PubMed  CAS  Google Scholar 

  • Dance, D. A., V. Wuthiekanun, P. Naigowit, and N. J. White. 1989 Identification of Pseudomonas pseudomallei in clinical practice: use of simple screening tests and API 20NE J. Clin. Pathol. 42 645–648

    Article  PubMed  CAS  Google Scholar 

  • Dance, D. A. 1990 Melioidosis Rev. Med. Microbiol. 1 143–150

    Google Scholar 

  • Dance, D. A. 1991 Melioidosis: The tip of the iceberg? Clin. Microbiol. Rev. 4 52–60

    PubMed  CAS  Google Scholar 

  • Darling, P., M. Chan, A. D. Cox, and P. A. Sokol. 1998 Siderophore production by cystic fibrosis isolates of Burkholderia cepacia Infect. Immunol. 66(2) 874–877

    CAS  Google Scholar 

  • DeShazer, D., P. Brett, R. Carlyon, and D. E. Woods. 1997 Mutagenesis of Burkholderia pseudomallei with Tn 5-OT182: isolation of motility mutants and molecular characterization of the flagellin structural gene J. Bacteriol. 179 2116–2125

    PubMed  CAS  Google Scholar 

  • DeShazer, D., P. Brett, and D. E. Woods. 1998 The Type II O-antigen moiety of Burkholderia pseudomallei lipo-polysaccharide is required for serum resistance and virulence Molec. Microbiol. 30 1011–1081

    Article  Google Scholar 

  • Deshazer, D., and D. E. Woods. 1999 Pathogenesis of melioidosis: Use of Tn5-OT182 to study the molecular basis of Burkholderia pseudomallei virulence J. Infect. Dis. Antimicrob. Ag. 16 91–96

    Google Scholar 

  • Ellison, D. W., H. J. Baker, and M. Mariappan. 1969 Melioidosis in Malaysia. I: A method of isolation of Pseudomonas pseudomallei from soil and surface water Am. J. Trop. Med. Hyg. 18 694–697

    PubMed  CAS  Google Scholar 

  • Esselman, M. T., and P. V. Liu. 1961 Lecithinase production by Gram-negative bacteria J. Bacteriol. 81 939–945

    Google Scholar 

  • Frangolias, D. D., E. Mahenthiralingam, S. Rae, J. M. Raboud, A. G. F. Davidson, R. Wittmann, and P. G. Wilcox. 1999 Burkholderia cepacia in cystic fibrosis: Variable disease course Am. J. Respir. Crit. Care Med. 160 1572–1577

    PubMed  CAS  Google Scholar 

  • Freeman, B. A. 1985 Pseudomonas and Legionella In: Burrow’s Textbook of Microbiology W. B. Saunders Co Philadelphia, PA 544–557

    Google Scholar 

  • Fritz, D. L, P. Vogel, D. R. Brown, and D. M. Waag. 1999 The hamster model of intraperitoneal Burkholderia mallei (glanders) Vet. Pathol. 36(4) 276–291

    Article  PubMed  CAS  Google Scholar 

  • Gilligan, P. H., P. A. Gage, L. M. Bradshaw, D. V. Schidlow, and B. T. DeCicco. 1985 Isolation medium for the recovery of Pseudomonas cepacia from respiratory secretions of patients with cystic fibrosis J. Clin. Microbiol. 22 5–8

    PubMed  CAS  Google Scholar 

  • Gilligan, P. H. 1991 Microbiology of airway disease in patients with cystic fibrosis Clin. Microbiol. Rev. 4(1) 35–51

    PubMed  CAS  Google Scholar 

  • Gilligan, P. H., and S. Whittier. 1999 Burkholderia, Stenotrophomonas, Ralstonia, Brevundimonas, Comamonas, and Acidovorax In: P. R. Murray, E. J. Baron, M. A. Pfaller, F. C. Tenover, and R. H. Yolken (Eds.) Manual of Clinical Microbiology ASM Press Washington DC.

    Google Scholar 

  • Gillis, M., T. V. Van, R. Bardin, M. Goor, P. Hebbar, A. Willems, P. Segers, K. Kersters, T. Heulin, and M. P. Fernandez. 1995 Polyphasic taxonomy in the genus Burkholderia leading to an amended description of the genus and proposition of Burkholderia vietnamiensis sp. nov. for N2-fixing isolates from rice in Vietnam Int. J. Syst. Bacteriol. 45 274–289

    Article  CAS  Google Scholar 

  • Godfrey, A. J., S. Wong, D. A. Dance, W. Chaowagul, and L. E. Bryan. 1991 Pseudomonas pseudomallei resistance to beta-lactam antibiotics due to alterations in the chromosomally encoded beta-lactamase Antimicrob. Agents Chemother. 35 1635–1640

    Article  PubMed  CAS  Google Scholar 

  • Goldman, D. A., and J. D. Klinger. 1986 Pseudomonas cepacia: Biology, mechanisms of virulence, epidemiology J. Pediatr. 108 806–812

    Article  Google Scholar 

  • Govan, J. R., P. H. Brown, J. Maddison, C. J. Doherty, J. W. Nelson, M. Dodd, A. P. Greening, and A. K. Webb. 1993 Evidence for transmission of Pseudomonas cepacia by social contact in cystic fibrosis Lancet 342(8862) 15–19

    Article  PubMed  CAS  Google Scholar 

  • Govan, J. R., and V. Deretic. 1996a Microbial pathogenesis in cystic fibrosis: Mucoid Pseudomonas aeruginosa and Burkholderia cepacia Microbiol. Rev. 60(3) 539–574

    PubMed  CAS  Google Scholar 

  • Govan, J. R., J. E. Hughes, and P. Vandamme. 1996b Burkholderia cepacia: Medical, taxonomic and ecological issues J. Med. Microbiol. 45(6) 395–407

    Article  PubMed  CAS  Google Scholar 

  • Haase, A., J. Janzen, S. Barrett, and B. Currie. 1997 Toxin production by Burkholderia pseudomallei strains and correlation with severity of melioidosis J. Med. Microbiol. 46 557–563

    Article  PubMed  CAS  Google Scholar 

  • Haubler, S., M. Nimtz, T. Domke, V. Wray, and I. Steinmetz. 1998 Purification and characterization of a cytotoxic exolipid of Burkholderia pseudomallei Infect. Immunol. 66 1588–1593

    CAS  Google Scholar 

  • Heckly, R. J., and C. Nigg. 1958 Toxins of Pseudomonas pseudomallei. II: Characterization J. Bacteriol. 76 427–436

    PubMed  CAS  Google Scholar 

  • Heckly, R. J. 1964 Differentiation of exotoxin and other biologically active substances in Pseudomonas pseudomallei filtrates J. Bacteriol. 88 1730–1736

    PubMed  CAS  Google Scholar 

  • Henry, D. A., M. E. Campbell, J. J. LiPuma, and D. P. Speert. 1997 Identification of Burkholderia cepacia isolates from patients with cystic fibrosis and use of a simple new selective medium J. Clin. Microbiol. 35 614–619

    PubMed  CAS  Google Scholar 

  • Henry, D. A., M. Campbell, C. McGimpsey, A. Clarke, L. Louden, J. Burns, M. H. Roe, P. Vandamme, and D. Speert. 1999 Comparison of isolation media for recovery of Burkholderia cepacia complex from respiratory secretions of patients with cystic fibrosis J. Clin. Microbiol. 37 1004–1007

    PubMed  CAS  Google Scholar 

  • Ho, M., T. Schollaardt, M. D. Smith, M. B. Perry, P. J. Brett, W. Chaowagul, and L. E. Bryan. 1997 Specificity and functional activity of anti-Burkholderia pseudomallei polysaccharide antibodies Infect. Immunol. 65 3648–3653

    CAS  Google Scholar 

  • Holmes, A., R. Nolan, R. Taylor, R. Finley, M. Riley, R. Z. Jiang, S. Steinbach, and R. Goldstein. 1999 An epidemic of Burkholderia cepacia transmitted between patients with and without cystic fibrosis J. Infect. Dis. 179(5) 1197–1205

    Article  PubMed  CAS  Google Scholar 

  • Hornick, R. B. 1982 Diseases due to Pseudomonas mallei and Pseudomonas pseudomallei In: R. J. Wedgewood (Ed.) Infections in Children Harper & Row Philadelphia, PA 910–913

    Google Scholar 

  • Howe, C. 1949 Glanders In: H. A. Christian (Ed.) The Oxford Medicine Oxford University Press New York, NY 185–201

    Google Scholar 

  • Howe, C., A. Sampath, and M. Spotnitz. 1971 The Pseudomallei group: A review J. Infect. Dis. 124 598–606

    Article  PubMed  CAS  Google Scholar 

  • Hutchison, M. L., I. R. Poxton, and J. R. Govan. 1998 Burkholderia cepacia produces a hemolysin that is capable of inducing apoptosis and degranulation of mammalian phagocytes Infect. Immunol. 66(5) 2033–2039

    CAS  Google Scholar 

  • Inglis, T. J. J., S. C. Garrow, C. Adams, M. Henderson, and M. Mayo. 1998 Dry season outbreak of melioidosis in Western Australia Lancet 352 1600

    Article  PubMed  CAS  Google Scholar 

  • Isles, A., I. Maclusky, M. Corey, R. Gold, C. Prober, P. Fleming, and H. Levison. 1984 Pseudomonas cepacia infection in cystic fibrosis: An emerging problem J. Pediatr. 104(2) 206–210

    Article  PubMed  CAS  Google Scholar 

  • Ismail, G., M. N. Embi, O. Omar, and N. Razak. 1987 Toxigenic properties of Pseudomonas pseudomallei extracellular products Trop. Biomed. 4 101–110

    Google Scholar 

  • Ismail, G., N. Razak, R. Mohamed, N. Embi, and O. Omar. 1988 Resistance of Pseudomonas pseudomallei to normal human serum bactericidal action Microbiol. Immunol. 32 645–652

    PubMed  CAS  Google Scholar 

  • Johnson, W. M., S. D. Tyler, and K. R. Rozee. 1994 Linkage analysis of geographic and clinical clusters in Pseudomonas cepacia infections by multilocus enzyme electrophoresis and ribotyping J. Clin. Microbiol. 32(4) 924–930

    PubMed  CAS  Google Scholar 

  • Kanai, K., and E. Kondo. 1994 Recent advances in biomedical sciences of Burkholderia pseudomallei (basonym: Pseudomonas pseudomallei) Jpn. J. Med. Sci. Biol. 47 1–45

    PubMed  CAS  Google Scholar 

  • Kenny, D. J., P. Russell, D. Rogers, S. M. Eley, and R. W. Titball. 1999 In vitro susceptibilities of Burkholderia mallei in comparison to those of other pathogenic Burkholderia spp. Antimicrob. Agents Chemother. 43(11);Nov 2773–2775

    PubMed  CAS  Google Scholar 

  • Knirel, Y. A., N. A. Paramonov, A. S. Shashkov, N. K. Kochetkov, R. G. Yarullin, S. M. Farber, and V. I. Efremenko. 1992 Structure of the polysaccharide chains of Pseudomonas pseudomallei lipopolysaccharides Carbohydr. Res. 233 185–193

    Article  PubMed  CAS  Google Scholar 

  • Kooi, C., A. Cox, P. Darling, and P. A. Sokol. 1994 Neutralizing monoclonal antibodies to an extracellular Pseudomonas cepacia protease Infect. Immunol. 62(7) 2811–2817

    CAS  Google Scholar 

  • Kovalev, G. K. 1971 Glanders (review) Zh. Mikrobiol. Edidemiol. Immunobiol. 48 63–70

    CAS  Google Scholar 

  • Leelarasamee, A., and S. Bovornkitti. 1989 Melioidosis: Review and update Rev. Infect. Dis. 11 413–425

    Article  PubMed  CAS  Google Scholar 

  • Lewenza, S., B. Conway, E. P. Greenberg, and P. A. Sokol. 1999 Quorum sensing in Burkholderia cepacia: identification of the LuxRI homologs CepRI J. Bacteriol. 181(3) 748–756

    PubMed  CAS  Google Scholar 

  • LiPuma, J. J., J. E. Mortensen, S. E. Dasen, T. D. Edlind, D. V. Schidlow, J. L. Burns, and T. L. Stull. 1988 Ribotype analysis of Pseudomonas cepacia J. Infect. Dis. 1164 133–136

    Google Scholar 

  • LiPuma, J. J., S. E. Dasen, D. W. Neilson, R. C. Stern, and T. L. Stull. 1990 Person-to-person transmission of Pseudomonas cepacia between patients with cystic fibrosis Lancet 336 527–532

    Article  Google Scholar 

  • LiPuma, J. J. 1998 Burkholderia cepacia: Management issues and new insights Clin. Chest Med. 19(3) 473–486, vi

    Article  PubMed  CAS  Google Scholar 

  • Lonon, M. K., D. E. Woods, and D. C. Straus. 1988 Production of lipase by clinical isolates of Pseudomonas cepacia J. Clin. Microbiol. 26(5) 979–984

    PubMed  CAS  Google Scholar 

  • Mahenthiralingam, E., M. E. Campbell, D. A. Henry, and D. A. Speert. 1996 Epidemiology of Burkholderia cepacia infection in patients with cystic fibrosis: Analysis by random amplified polymorphic DNA fingerprinting J. Clin. Microbiol. 34 2914–2920

    PubMed  CAS  Google Scholar 

  • Mahenthiralingam, E., D. A. Simpson, and D. P. Speert. 1997 Identification and characterization of a novel DNA marker associated with epidemic Burkholderia cepacia strains recovered from patients with cystic fibrosis J. Clin. Microbiol. 35(4) 808–816

    Google Scholar 

  • Mahenthiralingam, E., T. Coenye, J. W. Chung, D. P. Speert, J. R. W. Govan, P. Taylor, and P. Vandamme. 2000 Diagnostically and experimentally useful panel of strains from the Burkholderia cepacia complex J. Clin. Microbiol. 38(2) 910–913

    PubMed  CAS  Google Scholar 

  • Martin, D. W., and C. D. Mohr. 2000 Invasion and intracellular survival of Burkholderia cepacia Infect. Immunol. 68(1) 24–29

    Article  CAS  Google Scholar 

  • Masoud, H., M. Ho, T. Schollaardt, and M. B. Perry. 1997 Characterization of the capsular polysaccharide of Burkholderia (Pseudomonas) pseudomallei 304b J. Bacteriol. 179 5663–5669

    PubMed  CAS  Google Scholar 

  • Mays, E. E., and E. A. Ricketts. 1975 Melioidosis: Recrudescence associated with bronchogenic carcinoma twenty-six years following initial geographic exposure Chest 68 261–263

    Article  PubMed  CAS  Google Scholar 

  • McCormick, J. B., D. J. Sexton, J. G. McMurray, E. Carey, P. Hayes, and R. A. Feldman. 1975 Human-to-human transmission of Pseudomonas pseudomallei Ann. Internat. Med. 83 512–513

    CAS  Google Scholar 

  • McKevitt, A. I., and D. E. Woods. 1984 Characterization of Pseudomonas cepacia isolates from patients with cystic fibrosis J. Clin. Microbiol. 19(2) 291–293

    PubMed  CAS  Google Scholar 

  • McKevitt, A. I., S. Bajaksouzian, J. D. Klinger, and D. E. Woods. 1989 Purification and characterization of an extracellular protease from Pseudomonas cepacia Infect. Immunol. 57(3) 771–778

    CAS  Google Scholar 

  • Mietzner, T., and S. Morse. 1994 The role of iron-binding proteins in the survival of pathogenic bacteria Ann. Rev. Nutr. 14 471–493

    Article  CAS  Google Scholar 

  • Moens, S. M., and J. Vanderleyden. 1996 Functions of bacterial flagella Crit. Rev. Microbiol. 22 67–100

    Article  PubMed  CAS  Google Scholar 

  • Mortensen, J. E., M. C. Fisher, and J. J. LiPuma. 1995 Recovery of Pseudomonas cepacia and other Pseudomonas species from the environment Infect. Control. Hosp. Epidemiol. 16 30–32

    Article  PubMed  CAS  Google Scholar 

  • Nakazawa, T., Y. Yamada, and M. Ishibashi. 1987 Characterization of hemolysin in extracellular products of Pseudomonas cepacia J. Clin. Microbiol. 25(2) 195–198

    PubMed  CAS  Google Scholar 

  • Nigg, C., R. J. Heckly, and M. Colling. 1955 Toxin produced by Malleomyces pseudomallei Proc. Soc. Exp. Biol. Med. 89 17–20

    PubMed  CAS  Google Scholar 

  • Nijhuis, E. H., M. J. Maat, I. W. E. Zeegers, C. Waalwijk, and J. A. Van-Venn, J.A. 1993 Selection of bacteria suitable for introduction into the rhizosphere of grass Soil Biol. Biochem. 25 885–895

    Article  Google Scholar 

  • Nimtz, M., V. Wray, T. Domke, B. Brenneke, S. Haussler, and I. Steinmetz. 1997 Structure of an acidic exopolysaccharide of Burkholderia pseudomallei Eur. J. Biochem. 250 608–616

    Article  PubMed  CAS  Google Scholar 

  • Palleroni, N. J., and B. Holmes. 1981 Pseudomonas cepacia sp. nov., nom. rev Int. J. Syst. Bacteriol. 31 479–481

    Article  Google Scholar 

  • Parker, M. T. 1990 Glanders and melioidosis In: M. T. Parker and L. H. Collier (Eds.) Topley & Wilson’s Principles of Bacteriology, Virology and Immunity B. C. Decker Inc Philadelphia, PA 392–394

    Google Scholar 

  • Pegues, D. A., L. A. Carson, O. C. Tablan, S. C. FitzSimmons, S. B. Roman, J. M. Miller, and W. R. Jarvis. 1994 Acquisition of Pseudomonas cepacia at summer camps for patients with cystic fibrosis: Summer Camp Study Group J. Pediatr. 124(5, Part 1) 694–702

    Google Scholar 

  • Pegues, C. F., D. F. Pegues, D. S. Ford, P. L. Hibberd, L. A. Carson, C. M. Raine, and D. C. Hooper. 1996 Burkholderia cepacia respiratory acquisition: epidemiology and molecular characterization of a large nosocomial outbreak Epidemiol. Infect. 116 309–317

    Article  PubMed  CAS  Google Scholar 

  • Penn, C. W., and C. J. Luke. 1992 Bacterial flagellar diversity and significance in pathogenesis FEMS Microbiol. Lett. 100 331–336

    Google Scholar 

  • Perry, M. B., L. L. MacLean, T. Schollaardt, L. E. Bryan, and M. Ho. 1995 Structural characterization of the lipopolysaccharide O antigens of Burkholderia pseudomallei Infect. Immunol. 63 3348–3352

    CAS  Google Scholar 

  • Pitkin, D. H., W. Sheikh, and H. L. Nadler. 1997 Comparative in vitro activity of meropenem versus other extended-spectrum antimicrobials against randomly chosen and selected resistant clinical isolates tested in 26 North American centers Clin. Infect. Dis. 24(Suppl. 2) S238–S248

    Article  PubMed  CAS  Google Scholar 

  • Pitt, T. L. 1990 Pseudomonas mallei and P. pseudomallei In: M. T. Parker and L. H. Collier (Eds.) Topley & Wilson’s Principles of Bacteriology, Virology and Immunity B. C. Decker Inc Philadelphia, PA 265–268

    Google Scholar 

  • Pitt, T. L., H. Aucken, and D. A. Dance. 1992 Homogeneity of lipopolysaccharide antigens in Pseudomonas pseudomallei J. Infect. 25 139–146

    Article  PubMed  CAS  Google Scholar 

  • Prince, A. 1986 Antibiotic resistance of Pseudomonas species J. Pediatr. 108 830–834

    Article  PubMed  CAS  Google Scholar 

  • Pruksachartvuthi, S., N. Aswapokee, and K. Thakerngpol. 1990 Survival of Pseudomonas pseudomallei in human phagocytes J. Med. Microbiol. 31 109–114

    Article  PubMed  CAS  Google Scholar 

  • Pugsley, A. P. 1993 The complete general secretory pathway in Gram-negative bacteria Microbiol. Rev. 57 50–108

    PubMed  CAS  Google Scholar 

  • Ralston, E., N. J. Palleroni, and M. Doudoroff. 1973 Pseudomonas pickettii, a new species of clinical origin related to Pseudomonas solanacearum Int. J. Syst. Bacteriol. 23 15–19

    Article  Google Scholar 

  • Riboli, A. C., R. Koshinski, K. Arias, K. Marks-Austin, D. Stiertz, and T. L. Stull. 1996 An outbreak of Burkholderia cepacia lower respiratory tract infection associated with contaminated albuterol nebulization solution Infect. Control Hosp. Epidemiol. 17 741–743

    Article  Google Scholar 

  • Saini, L. S., S. B. Galsworthy, M. A. John, and M. A. Valvano. 1999 Intracellular survival of Burkholderia cepacia complex isolates in the presence of macrophage cell activation Microbiology 145(12) 3465–3475

    PubMed  CAS  Google Scholar 

  • Sanford, J. P. 1990 Principles and Practice of Infectious Diseases In: G. L. Mandell, R. G. Douglas Jr., and J. E. Bennett (Eds.) Churchill Livingstone New York, NY 1692–1696

    Google Scholar 

  • Sanford, J. P. 1995 Pseudomonas species including melioidosis and glanders In: G. L. Mandell, J. E. Bennett and R. Dolin (Eds.) Principles and Practice of Infectious Diseases, 4th ed Churchill Livingstone New York, NY 1250–1254

    Google Scholar 

  • Segonds, C., T. Heulin, N. Marty, and G. Chabanon. 1999 Differentiation of Burkholderia species by PCR-restriction fragment length polymorphism analysis of the 16S rRNA gene and application to cystic fibrosis isolates J. Clin. Microbiol. 37 2201–2208

    PubMed  CAS  Google Scholar 

  • Sexton, M. M., A. L. Jones, W. Chaowagul, and D. E. Woods. 1994 Purification and characterization of a protease from Pseudomonas pseudomallei Can. J. Microbiol. 40 903–910

    Article  PubMed  CAS  Google Scholar 

  • Simpson, I. N., J. Finlay, D. J. Winstanley, N. Dewhurst, J. W. Nelson, S. L. Butler, and J. R. Govan. 1994 Multi-resistance isolates possessing characteristics of both Burkholderia (Pseudomonas) cepacia and Burkholderia gladioli from patients with cystic fibrosis J. Antimicrob. Chemother. 34(3) 353–361

    Article  PubMed  CAS  Google Scholar 

  • Smith, C. J., J. C. Allen, M. N. Embi, O. Othman, N. Razak, and G. Ismail. 1987 Human melioidosis: An emerging medical problem MIRCEN J. 3 343–366

    Article  Google Scholar 

  • Smith, D. L., L. B. Gumery, E. G. Smith, D. E. Stableforth, M. E. Kaufmann, and T. L. Pitt. 1993 Epidemic of Pseudomonas cepacia in an adult cystic fibrosis unit: Evidence of person-to-person transmission J. Clin. Microbiol. 31(11) 3017–3022

    PubMed  CAS  Google Scholar 

  • Smith, M. D., V. Wuthiekanun, A. L. Walsh, and N. J. White. 1995 Quantitative recovery of Burkholderia pseudomallei from soil in Thailand Trans. R. Soc. Trop. Med. Hyg. 89 488–490

    Article  PubMed  CAS  Google Scholar 

  • Sokol, P. A. 1986 Production and utilization of pyochelin by clinical isolates of Pseudomonas cepacia J. Clin. Microbiol. 23(3) 560–562

    PubMed  CAS  Google Scholar 

  • Sokol, P. A., P. Darling, D. E. Woods, E. Mahenthiralingam, and C. Kooi. 1999 Role of ornibactin biosynthesis in the virulence of Burkholderia cepacia: characterization of pvdA, the gene encoding L-ornithine N(5)-oxygenase Infect. Immunol. 67(9) 4443–4455

    CAS  Google Scholar 

  • Sokol, P. A., C. Kooi, R. S. Hodges, P. Cachia, and D. E. Woods. 2000 Immunization with a Pseudomonas elastase peptide reduces severity of experimental lung infections due to Pseudomonas aeruginosa or Burkholderia cepacia J. Infect. Dis. 181 1682–1692

    Article  PubMed  CAS  Google Scholar 

  • Speert, D. P., M. Bond, R. C. Woodman, and J. T. Curnutte. 1994 Infection with Pseudomonas cepacia in chronic granulomatous disease: Role of nonoxidative killing by neutrophils in host defense J. Infect. Dis. 170(6) 1524–1531

    Article  PubMed  CAS  Google Scholar 

  • Steele, J. H. 1973 The zoonoses: An epidemiologist’s viewpoint In: M. Stefanini (Ed.) Progress in Clinical Pathology Grune and Stratton New York, NY 239–286

    Google Scholar 

  • Steinmetz, I., M. Rohde, and B. Brenneke. 1995 Purification and characterization of an exopolysaccharide of Burkholderia (Pseudomonas) pseudomallei Infect. Immunol. 63 3959–3965

    CAS  Google Scholar 

  • Sun, L., R. Z. Jiang, S. Steinbach, A. Holmes, C. Campanelli, J. Forstner, U. Sajjan, Y. Tan, M. Riley, and R. Goldstein. 1995 The emergence of a highly transmissible lineage of cbl+ Pseudomonas (Burkholderia) cepacia causing CF centre epidemics in North America and Britain Nat. Med. 1(7) 661–666

    Article  PubMed  CAS  Google Scholar 

  • Tanphaichitra, D., and S. Srimuang. 1984 Cellular immunity in tuberculosis, melioidoses, pasteurellosis, penicilliosis and role of levamisole and isoprinosine Dev. Biol. Stand. 57 117–123

    PubMed  CAS  Google Scholar 

  • Tanphaichitra, D. 1989 Tropical disease in the immunocompromised host: melioidosis and pythiosis Rev. Infect. Dis. 11(Suppl. 7) S1629–S1643

    Article  PubMed  Google Scholar 

  • Vandamme, P., B. Holmes, M. Vancanneyt, T. Coenye, B. Hoste, R. Coopman, H. Revets, S. Lauwers, M. Gillis, K. Kersters, and J. R. Govan. 1997 Occurrence of multiple genomovars of Burkholderia cepacia in cystic fibrosis patients and proposal of Burkholderia multivorans sp. nov Int. J. Syst. Bacteriol. 47(4) 1188–1200

    Article  PubMed  CAS  Google Scholar 

  • Vandamme, P., E. Mahenthiralingam, B. Holmes, T. Coenye, B. Hoste, P. De Vos, D. Henry, and D. P. Speert. 2000 Identification and population structure of Burkholderia stabilis sp. nov (formerly Burkholderia cepacia genomovar IV) J. Clin. Microbiol. 38 1042–1047

    PubMed  CAS  Google Scholar 

  • Von Graevenitz, A. 1973 Clinical microbiology of unusual Pseudomonas species Prog. Clin. Path. 5 185–218

    Google Scholar 

  • Weinberg, A. N., and H. M. Heller. 1997 Infectious Diseases of the Lung Thieme-Stratton New York, NY 2413–2430

    Google Scholar 

  • Welch, D. F., M. J. Muszynski, C. H. Pai, M. J. Maracon, M. M. Hribar, P. H. Gilligan, J. M. Matsen, P. A. Ahlin, B. C. Hilman, and S. A. Chartrand. 1987 Selective and differential medium for recovery of Pseudomonas cepacia from the respiratory tracts of patients with cystic fibrosis J. Clin. Microbiol. 25 1730–1734

    PubMed  CAS  Google Scholar 

  • Whitmore, A., and C. S. Krishnaswami. 1912 An account of the discovery of a hitherto undescribed infective disease occurring among the population of Rangoon Indian Med. Gaz. 47 262–267

    Google Scholar 

  • Whitmore, A. 1913 An account of a glanders-like disease occurring in Rangoon J. Hyg. Camb. 13 1–7

    Article  PubMed  CAS  Google Scholar 

  • Woods, D. E., A. L. Jones, and P. J. Hill. 1993 Interaction of insulin with Pseudomonas pseudomallei Infect. Immunol. 61 1914–1919

    Google Scholar 

  • Wuthiekanum, V., M. D. Smith, D. A. B. Dance, A. L. Walsh, T. L. Pitt, and N. J. White. 1996a Biochemical characteristics of clinical and environmental isolates of Burkholderia pseudomallei J. Med. Microbiol. 45 408–412

    Article  Google Scholar 

  • Wuthiekanum, V., M. D. Smith, D. A. B. Dance, A. L. Walsh, T. L. Pitt, and N. J. White. 1996b Isolation of Pseudomonas pseudomallei from soil in north-eastern Thailand Trans. R. Soc. Trop. Med. Hyg. 89 41–43

    Article  Google Scholar 

  • Yabuuchi, E., Y. Kosako, H. Oyaizu, I. Yano, H. Hotta, Y. Hashimoto, T. Ezaki, and M. Arakawa. 1992 Proposal of Burkholderia gen. nov. and transfer of seven species of the genus Pseudomonas homology group II to the new genus, with the type species Burkholderia cepacia (Palleroni and Holmes 1981) comb. nov Microbiol. Immunol. 36(12) 1251–1275

    PubMed  CAS  Google Scholar 

  • Yabuuchi, E., Y. Kosako, I. Yano, H. Hotta, and Y. Nishiuchi. 1995 Transfer of two Burkholderia and an Alcaligenes species to Ralstonia gen. nov.: Proposal of Ralstonia pickettii (Ralston, Palleroni and Doudoroff 1973) comb. nov., Ralstonia solanacearum (Smith 1896) comb. nov. and Ralstonia eutropha (Davis 1969) comb. nov Microbiol. Immunol. 39 897–904

    PubMed  CAS  Google Scholar 

  • Yang, H. M., W. Chaowagul, and P. A. Sokol. 1991 Siderophore production by Pseudomonas pseudomallei Infect. Immunol. 59 776–780

    CAS  Google Scholar 

  • Yang, H. M., C. D. Kooi, and P. A. Sokol. 1993 Ability of Pseudomonas pseudomallei malleobactin to acquire transferrin-bound, lactoferrin-bound, and cell-derived iron Infect. Immunol. 61 656–662

    CAS  Google Scholar 

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Authors
  1. Donald E. Woods
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  2. Pamela A. Sokol
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Editor information

Editors and Affiliations

  1. Department of Microbiology, University of Minnesota, Box 196, Twin Cities, Minneapolis, MN 55455-0312, USA

    Martin Dworkin Professor Dr. (Editor-in-Chief) (Editor-in-Chief)

  2. Department of Microbiology and Immunology, Stanford University Medical School, 299 Campus Drive, Fairchild, D039, Stanford, CA, 94305-5124, USA

    Stanley Falkow

  3. Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Ramat-Aviv, 69978, Israel

    Eugene Rosenberg

  4. Department of Microbiology, Technical University Munich, 80290, Munich, Germany

    Karl-Heinz Schleifer

  5. DSMZ- German Collection of Microorganisms and Cell Cultures GmbH, Mascheroder Weg 1b, 38124, Braunschweig, Germany

    Erko Stackebrandt

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Woods, D.E., Sokol, P.A. (2006). The Genus Burkholderia . In: Dworkin, M., Falkow, S., Rosenberg, E., Schleifer, KH., Stackebrandt, E. (eds) The Prokaryotes. Springer, New York, NY. https://doi.org/10.1007/0-387-30745-1_40

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