Stimuli-Responsive Self-Assembly Based on Macrocyclic Hosts and Biomedical Applications

  • Weipeng Mao
  • Da MaEmail author
Living reference work entry


Macrocyclic hosts have been used to construct stimuli-responsive self-assembly systems. Stimuli types include pH, reducing environment, reactive oxygen species, and photo-irradiation. Self-assembled microparticles, nanoparticles, or hydrogels have versatile biomedical applications, including drug delivery, bioimaging, and theranostics. The use of macrocyclic hosts could improve the complexity of self-assembly systems. Importantly, host-guest interaction has been used as biorthogonal stimuli to other stimuli types. These macrocyclic host-based stimuli-responsive self-assembly systems have achieved unique biomedical purpose in vitro or in vivo.


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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  1. 1.Department of ChemistryFudan UniversityShanghaiChina

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