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Overview of Women and Addiction

  • Florence ThibautEmail author
Reference work entry
  • 37 Downloads
Part of the Mental Health and Illness Worldwide book series (MHIW)

Abstract

Women are gradually losing the protection they had from historic social roles. In general, girls and women seem more influenced by beliefs about weight control and self-image as well as by female friends or role models when they use alcohol or tobacco. As compared to men, women more often use psychoactive substances to cope with stress and negative feelings. Pharmacokinetics and pharmacodynamics differences, reward process specificities, and female hormones play a major role in gender differences observed in addictive behaviors. Therefore, health consequences differ. Finally, women’s consumption of psychoactive substances may be associated with serious birth and developmental consequences in babies exposed during pregnancy.

Further research is needed, especially concerning treatment features according to gender.

Keywords

Women Addiction Alcohol Tobacco Illicit drugs Pregnancy Gender 

References

  1. Allen AM, Weinberger AH, Wetherill RR, Howe CL, McKee SA (2017) Oral contraceptives and cigarette smoking: a review of the literature and future directions. Nicotine Tob Res 21:592.  https://doi.org/10.1093/ntr/ntx258CrossRefPubMedCentralGoogle Scholar
  2. Anker JJ, Carroll ME (2011) Females are more vulnerable to drug abuse than males: evidence from preclinical studies and the role of ovarian hormones. Curr Top Behav Neurosci 8:73–96CrossRefPubMedPubMedCentralGoogle Scholar
  3. Becker JB (2016) Sex differences in addiction. Dialogues Clin Neurosci 18(4):395–402PubMedPubMedCentralGoogle Scholar
  4. Becker JB, Hu M (2008) Sex differences in drug abuse. Front Neuroendocrinol 29(1):36–47CrossRefPubMedPubMedCentralGoogle Scholar
  5. Benowitz NL, Hatsukami D (1998) Gender differences in the pharmacology of nicotine addiction. Addict Biol 3(4):383–404CrossRefPubMedPubMedCentralGoogle Scholar
  6. Berlin I, Singleton EG, Pedarriosse AM, Lancrenon S, Rames A, Aubin HJ et al (2003) The modified reasons for smoking scale. Factorial structure, gender effects and relationship with nicotine dependence and smoking cessation in French smokers. Addiction 98:1575–1583CrossRefPubMedPubMedCentralGoogle Scholar
  7. Boardman JD, Saint Onge JM, Haberstick BC, Timberlake DS, Hewitt JK (2008) Do schools moderate the genetic determinants of smoking? Behav Genet 38(3):234–246CrossRefPubMedPubMedCentralGoogle Scholar
  8. Borrelli B, Bock B, King T, Pinto B, Marcus BH (1996) The impact of depression on smoking cessation in women. Am J Prev Med 12(5):378–387CrossRefPubMedPubMedCentralGoogle Scholar
  9. Brady KT, Randall CL (1999) Gender differences in substance use disorders. Psychiatr Clin North Am 22(2):241–252CrossRefPubMedPubMedCentralGoogle Scholar
  10. Bush K, Kivlahan DR, McDonell MB, Fihn SD, Bradley KA (1998) The AUDIT alcohol consumption questions (AUDIT-C): an effective brief screening test for problem drinking. Ambulatory Care Quality Improvement Project (ACQUIP). Alcohol Use Disorders Identification Test. Arch Intern Med 158(16):1789–1795CrossRefGoogle Scholar
  11. Carroll ME, Lynch WJ (2016) How to study sex differences in addiction using animal models? Addict Biol 21(5):1007–1029CrossRefPubMedPubMedCentralGoogle Scholar
  12. Carroll ME, Lynch WJ, Roth ME, Morgan AD, Cossgrove KP (2004) Sex and oestrogen influence drug abuse. Trends Pharmacol Sci 25(5):273–279CrossRefPubMedGoogle Scholar
  13. Chassin L, Presson CC, Rose JS, Sherman SJ (1996) The natural history of cigarette smoking from adolescence to adulthood: demographic predictors of continuity and change. Health Psychol 15(6):478–484CrossRefPubMedGoogle Scholar
  14. Chassin L, Presson C, Seo DC, Sherman SJ, Macy J, Wirth RJ, Curran P (2008) Multiple trajectories of cigarette smoking and the intergenerational transmission of smoking: a multigenerational, longitudinal study of a Midwestern community sample. Health Psychol 27(6):819–828CrossRefPubMedGoogle Scholar
  15. Cook JL, Green CR, Lilley CM, Anderson SM, Baldwin ME, Chudley AE, Conry JL, LeBlanc N, Loock CA, Lutke J, Mallon BF, McFarlane AA, Temple VK, Rosales T, Canada Fetal Alcohol Spectrum Disorder Research Network (2016) Fetal alcohol spectrum disorder: a guideline for diagnosis across the lifespan. CMAJ 188(3):191–197CrossRefPubMedPubMedCentralGoogle Scholar
  16. Crawford-Williams F, Fielder A, Mikockla-Walus A, Esterman A (2015) A critical review of public health interventions aimed at reducing alcohol consumption and/or increasing knowledge among pregnant women. Drug Alcohol Rev 34(2):154–161CrossRefPubMedGoogle Scholar
  17. Cui Y, Shooshtari S, Forget E, Clara I, Cheung KF (2014) Smoking during pregnancy: findings from the 2009–2010 Canadian Community Health Survey. PLoS One 9(1):e84640CrossRefPubMedPubMedCentralGoogle Scholar
  18. Degenhardt L, Whiteford HA, Ferrari AJ, Baxter AJ, Charlson FJ, Hall WD, Freedman G, Burstein R, Johns N, Engell RE, Flaxman A, Murray CJ, Vos T (2013) Global burden of disease attributable to illicit drug use and dependence: findings from the Global Burden of Disease Study 2010. Lancet 382(9904):1564–1574CrossRefPubMedGoogle Scholar
  19. Del Campo M, Jones KL (2017) A review of the physical features of the fetal alcohol spectrum disorders. Eur J Med Genet 60(1):55–64CrossRefPubMedGoogle Scholar
  20. Dluzen DE, Liu B (2008) Gender differences in methamphetamine use and responses: a review. Gend Med 5(1):24–35CrossRefPubMedGoogle Scholar
  21. Erol A, Karpyak VM (2015) Sex and gender-related differences in alcohol use and its consequences: contemporary knowledge and future research considerations. Drug Alcohol Depend 156:1–13CrossRefPubMedGoogle Scholar
  22. Evans JL, Hahn JA, Page-Shafer K, Lum PJ, Stein ES, Davidson PJ, Moss AR (2003) Gender differences in sexual and injection risk behavior among active young injection drug users in San Francisco (the UFO Study). J Urban Health 80(1):137–146CrossRefPubMedPubMedCentralGoogle Scholar
  23. Fattore L, Melis M (2016) Sex differences in impulsive and compulsive behaviors: a focus on drug addiction. Addict Biol 21:1043–1051CrossRefPubMedGoogle Scholar
  24. Fox HC, Sinha R (2009) Sex differences in drug-related stress-system changes: implications for treatment in substance-abusing women. Harv Rev Psychiatry 17(2):103–119CrossRefPubMedPubMedCentralGoogle Scholar
  25. Franconi F, Campesi I, Occhioni S, Antonini P, Murphy MF (2012) Sex and gender in adverse drug events, addiction, and placebo. Handb Exp Pharmacol 214:107–126CrossRefGoogle Scholar
  26. French SA, Perry CL (1996) Smoking among adolescent girls: prevalence and etiology. J Am Med Womens Assoc (1972) 51(1–2):25–28Google Scholar
  27. Fulkerson JA, French SA (2003) Cigarette smoking for weight loss or control among adolescents: gender and racial/ethnic differences. J Adolesc Health 32:306–313CrossRefPubMedPubMedCentralGoogle Scholar
  28. Gowing LR, Ali RL, Alisop S, Marsden J, Turf EE, West R, Witton J (2015) Global statistics on addictive behaviours: 2014 status report. Addiction 110(6):904–919CrossRefPubMedGoogle Scholar
  29. Griffin ML, Weiss RD, Mirin SM, Lange U (1989) A comparison of male and female cocaine abusers. Arch Gen Psychiatry 46(2):122–126CrossRefPubMedGoogle Scholar
  30. Henderson J, Gray R, Brocklehurst P (2007) Systematic review of the effects of low-moderate prenatal alcohol exposure on pregnancy outcome. BJOG 114(3):243–352CrossRefGoogle Scholar
  31. International Center for Alcohol Policies (ICAP) (2013) Minimum age limits worldwide. Washington, DC: Author.Google Scholar
  32. Ion RC, Wills AK, Bernal AL (2015) Environmental tobacco smoke exposure in pregnancy is associated with earlier delivery and reduced birth weight. Reprod Sci 22(12):1603–1611CrossRefGoogle Scholar
  33. Jacobs E, D’Esposito M (2011) Estrogen shapes dopamine-dependent cognitive processes: implications for women’s health. J Neurosci 31(14):5286–5293CrossRefPubMedPubMedCentralGoogle Scholar
  34. Jemal A, Thun MJ, Ries LA, Howe HL, Weir HK, Center MM, Ward E, Wu XC, Eheman C, Anderson R, Ajani UA, Kohler B, Edwards BK (2008) Annual report to the nation on the status of cancer, 1975–2005, featuring trends in lung cancer, tobacco use, and tobacco control. J Natl Cancer Inst 100(23):1672–1694CrossRefPubMedPubMedCentralGoogle Scholar
  35. Kendler KS, Chen X, Dick D, Maes H, Gillespie N, Neale MC, Riley B (2012) Recent advances in the genetic epidemiology and molecular genetics of substance use disorders. Nat Neurosci 15(2):181–189CrossRefPubMedPubMedCentralGoogle Scholar
  36. Kuehner C (2017) Why is depression more common among women than among men? Lancet Psychiatry 4:146–158CrossRefGoogle Scholar
  37. Kuhn C (2015) Emergence of sex differences in the development of substance use and abuse during adolescence. Pharmacol Ther 153:55–78CrossRefPubMedPubMedCentralGoogle Scholar
  38. Kuhn C, Johnson M, Thomae A, Luo B, Simon SA, Zhou G, Walker QD (2010) The emergence of gonadal hormone influences on dopaminergic function during puberty. Horm Behav 58(1):122–137CrossRefGoogle Scholar
  39. Lamy S, Thibaut F (2010) Psychoactive substance use during pregnancy: a review. Encéphale 36(1):33–38CrossRefGoogle Scholar
  40. Lamy S, Laqueille X, Thibaut F (2015) Consequences of tobacco, cocaine and cannabis consumption during pregnancy on the pregnancy itself, on the newborn and on child development: a review. Encéphale 41(1):13–20CrossRefGoogle Scholar
  41. Lamy S, Hennart B, Houivet E, Dulaurent S, Delavenne H, Benichou J, Allorge D, Marret S, Thibaut F, Perinatal Network of Upper-Normandy (2017) Assessment of tobacco, alcohol and cannabinoid metabolites in 645 meconium samples of newborns compared to maternal self-reports. J Psychiatr Res 90:86–93CrossRefGoogle Scholar
  42. Lamy S, Houivet E, Marret S, Hennart B, Delavenne H, Benichou J, Allorge D, Thibaut F, Perinatal Network of Upper-Normandy (2019) Risk factors associated to tobacco and alcohol use in a large French cohort of pregnant women. Arch Womens Ment Health 22(2):267–277CrossRefGoogle Scholar
  43. Latino-Martel P, Arwidson P, Ancellin R, Druesne-Pecollo N, Hercberg S, Le Quellec-Nathan M, Le-Luong T, Maraninchi D (2011) Alcohol consumption and cancer risk: revisiting guidelines for sensible drinking. CMAJ 183(16):1861–1865CrossRefPubMedPubMedCentralGoogle Scholar
  44. Lemoine P, Harousseau H, Borteyru JP, Menuet JC (1968) Les enfants de parents alcooliques – anomalies observées: à propos de 127 cas. Ouest Med 21:476–482Google Scholar
  45. Lynch WJ, Roth ME, Carroll ME (2002) Biological basis of sex differences in drug abuse: preclinical and clinical studies. Psychopharmacology (Berl) 164(2):121–137CrossRefGoogle Scholar
  46. MacDermott LJ, Dobson AJ, Owen N (2006) From partying to parenthood: young women’s perceptions of cigarette smoking across life transitions. Health Educ Res 21:428–439CrossRefGoogle Scholar
  47. MacLaren VV, Best LA (2010) Multiple addictive behaviors in young adults: student norms for the shorter PROMIS questionnaire. Addict Behav 35:252–255CrossRefPubMedCentralGoogle Scholar
  48. Mathur C, Stigler MH, Perry CL, Arora M, Reddy KS (2008) Differences in prevalence of tobacco use among Indian urban youth: the role of socioeconomic status. Nicotine Tob Res 10(1):109–116CrossRefPubMedPubMedCentralGoogle Scholar
  49. Mathur C, Stigler MH, Erickson DJ, Perry CL, Arora M, Reddy KS (2014) Change in tobacco use over time in urban Indian youth: the moderating role of socioeconomic status. Health Educ Behav 41(2):121–126CrossRefPubMedPubMedCentralGoogle Scholar
  50. Mozley LH, Gur RC, Mozley PD, Gur RE (2001) Striatal dopamine transporters and cognitive functioning in healthy men and women. Am J Psychiatry 158(9):1492–1429CrossRefPubMedGoogle Scholar
  51. Nichter M, Nichter M, Van Sickle D (2004) Popular perceptions of tobacco products and patterns of use among male college students in India. Soc Sci Med 59:415–431CrossRefPubMedGoogle Scholar
  52. O’Leary CM, Bower C (2012) Guidelines for pregnancy: what’s an acceptable risk, and how is the evidence (finally) shaping up? Drug Alcohol Rev 31(2):170–183CrossRefPubMedGoogle Scholar
  53. Patra J, Taylor B, Irving H, Roerecke M, Baliunas D, Mohapatra S, Rehm J (2010) Alcohol consumption and the risk of morbidity and mortality for different stroke types – a systematic review and meta-analysis. BMC Public Health 10:258CrossRefPubMedPubMedCentralGoogle Scholar
  54. Pirie PL, Murray DM, Luepker RV (1991) Gender differences in cigarette smoking and quitting in a cohort of young adults. Am J Public Health 81(3):324–327CrossRefPubMedPubMedCentralGoogle Scholar
  55. Pirie K, Peto R, Reeves GK, Green J, Beral V, Million Women Study Collaborators (2013) The 21st century hazards of smoking and benefits of stopping: a prospective study of one million women in the UK. Lancet 381(9861):133–141CrossRefPubMedPubMedCentralGoogle Scholar
  56. Popova S, Lange S, Probst C, Gmel G, Rehm J (2017) Estimation of national, regional, and global prevalence of alcohol use during pregnancy and fetal alcohol syndrome: a systematic review and meta-analysis. Lancet Glob Health 5(3):290–299CrossRefGoogle Scholar
  57. Potenza MN, Hong KI, Lacadie CM, Fulbright RK, Tuit KL, Sinha R (2012) Neural correlates of stress-induced and cue-induced drug craving: influences of sex and cocaine dependence. Am J Psychiatry 169(4):406–414CrossRefPubMedPubMedCentralGoogle Scholar
  58. Quinones-Jenab V, Jenab S (2010) Progesterone attenuates cocaine-induced responses. Horm Behav 58(1):22–32CrossRefPubMedGoogle Scholar
  59. Reddy KS, Gupta PC (eds) (2004) Report on tobacco control in India. Ministry of Health & Family Welfare, Government of India, MumbaiGoogle Scholar
  60. Rehm J, Shield KD, Roerecke M, Gmel G (2016) Modelling the impact of alcohol consumption on cardiovascular disease mortality for comparative risk assessments: an overview. BMC Public Health 16:36CrossRefGoogle Scholar
  61. Ribassin-Majed L, Hill C (2015) Trends in tobacco-attributable mortality in France. Eur J Pub Health 5(5):824–828CrossRefGoogle Scholar
  62. Samet JM, Yoon SY (eds) (2010) Gender, women and the tobacco epidemic. WHO, GenevaGoogle Scholar
  63. Sarton E, Olofsen E, Romberg R, den Hartigh J, Kest B, Nieuwenhuijs D, Burm A, Teppema L, Dahan A (2000) Sex differences in morphine analgesia: an experimental study in healthy volunteers. Anesthesiology 93(5):1245–1254CrossRefPubMedGoogle Scholar
  64. Schütze M, Boeing H, Pischon T, Rehm J, Kehoe T, Gmel G, Olsen A, Tjønneland AM, Dahm CC, Overvad K, Clavel-Chapelon F et al (2011) Alcohol attributable burden of incidence of cancer in eight European countries based on results from prospective cohort study. BMJ 342:d1584CrossRefPubMedPubMedCentralGoogle Scholar
  65. Skagerström J, Chang G, Nilsen P (2011) Predictors of drinking during pregnancy: a systematic review. J Womens Health 20(6):901–913CrossRefGoogle Scholar
  66. Slade T, Chapman C, Swift W, Keyes K, Tonks Z, Teesson M (2016) Birth cohort trends in the global epidemiology of alcohol use and alcohol-related harms in men and women: systematic review and metaregression. BMJ Open 6(10):e011827CrossRefPubMedPubMedCentralGoogle Scholar
  67. Slater SJ, Chaloupka FJ, Wakefield M, Johnston LD, O’Malley PM (2007) The impact of retail cigarette marketing practices on youth smoking uptake. Arch Pediatr Adolesc Med 161(5):440–445CrossRefPubMedGoogle Scholar
  68. Smedberg J, Lupattelli A, Mårdby AC, Nordeng H (2014) Characteristics of women who continue smoking during pregnancy: a cross-sectional study of pregnant women and new mothers in 15 European countries. BMC Pregnancy Childbirth 14:213CrossRefPubMedPubMedCentralGoogle Scholar
  69. Soldin OP, Mattison DR (2009) Sex differences in pharmacokinetics and pharmacodynamics. Clin Pharmacokinet 48(3):143–157CrossRefPubMedPubMedCentralGoogle Scholar
  70. Terner JM, de Wit H (2006) Menstrual cycle phase and responses to drugs of abuse in humans. Drug Alcohol Depend 84(1):1–13CrossRefPubMedPubMedCentralGoogle Scholar
  71. Thibaut F (2016) The role of sex and gender in neuropsychiatric disorders. Dialogues Clin Neurosci 18(4):351–352PubMedPubMedCentralGoogle Scholar
  72. Thibaut F (2017) Gender does matter in clinical research. Eur Arch Psychiatry Clin Neurosci 267(4):283–284CrossRefPubMedPubMedCentralGoogle Scholar
  73. Thibaut F, Chagraoui A, Buckley L, Gressier F, Labad J, Lamy S, Potenza M, Rondon M, Rössler A, Soyka M, Yonkers K (2019) WFSBP and IAWMH guidelines for the treatment of alcohol use disorders in pregnant women. World J Biol Psychiatry 20(1):17–50CrossRefPubMedPubMedCentralGoogle Scholar
  74. Tomeo CA, Field AE, Berkey CS, Colditz GA, Frazier AL (1999) Weight concerns, weight control behaviors, and smoking initiation. Pediatrics 104(4 Pt 1):918–924CrossRefGoogle Scholar
  75. Tyas SL, Pederson LL (1998) Psychosocial factors related to adolescent smoking: a critical review of the literature. Tob Control 7(4):409–420CrossRefPubMedPubMedCentralGoogle Scholar
  76. Uban KA, Rummel J, Floresco SB, Galea LA (2012) Estradiol modulates effort-based decision making in female rats. Neuropsychopharmacology 37(2):390–401CrossRefGoogle Scholar
  77. Volkow ND, Wang GJ, Fowler JS, Thanos PP, Logan J, Gatley SJ, Gifford A, Ding YS, Wong C, Pappas N (2002) Brain DA D2 receptors predict reinforcing effects of stimulants in humans: replication study. Synapse 46(2):79–82CrossRefGoogle Scholar
  78. Weinstein ND, Marcus SE, Moser RP (2005) Smokers’ unrealistic optimism about their risk. Tob Control 14(1):55–59CrossRefPubMedPubMedCentralGoogle Scholar
  79. West R, McEwen M, Bates C (1999) Sex and smoking: comparisons between male and female smokers. No Smoking Day, London. http://www.rjwest.co.uk/resources/sexandsmoking.pdfGoogle Scholar
  80. Whiteford HA, Degenhardt L, Rehm J, Baxter AJ, Ferrari AJ, Erskine HE, Charlson FJ, Norman RE, Flaxman AD, Johns N, Burstein R, Murray CJ, Vos T (2013) Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010. Lancet 382(9904):1575–1586CrossRefPubMedGoogle Scholar
  81. Wilhelm K, Wedgwood L, Niven H, Kay-Lambkin F (2006) Smoking cessation and depression: current knowledge and future directions. Drug Alcohol Rev 25(1):97–107CrossRefGoogle Scholar
  82. World Health Organization (2014a) World Health Organization (WHO) global report: mortality attributable to tobacco. World Health Organization 2012. World Health Organization (WHO): global status report on alcohol and health. World Health Organization, GenevaGoogle Scholar
  83. World Health Organization (2014b) World Health Organization (WHO): guidelines for the identification and management of substance use and substance use disorders in pregnancy. World Health Organization, GenevaGoogle Scholar
  84. Zilberman M, Tavares H, El-Guebaly N (2003) Gender similarities and differences: the prevalence and course of alcohol- and other substance-related disorders. J Addict Dis 22(4):61–74CrossRefGoogle Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2020

Authors and Affiliations

  1. 1.Department of Psychiatry and AddictionUniversity Hospital Cochin (site Tarnier), Paris University, INSERM 1266, Institute of Psychiatry and NeurosciencesParisFrance

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