Entities That Can Present as IU/Vitritis

  • Tripti Chaudhary
  • Reema BansalEmail author
Living reference work entry


Different terminologies have evolved over the years to describe inflammation of the ciliary body, such as cyclitis, vitritis, and peripheral uveitis. As per the “International Uveitis Study Group” (IUSG) and “Standardization of Uveitis Nomenclature” (SUN), the term “intermediate uveitis” (IU) is an anatomical classification, and refers to inflammation mainly involving the anterior vitreous, ciliary body, and peripheral retina, with minimal or no inflammation of the anterior or posterior segment. Various entities (infectious or noninfectious) can present as IU or vitritis, such as sarcoidosis, tuberculosis, Lyme disease, and multiple sclerosis. Pars planitis is an idiopathic subset of IU, characterized by vitreous cells, snow balls, and snow banks, which is almost always bilateral with no posterior synechiae. The disease usually begins with mild visual symptoms like floaters or blurred vision, and the eyes are white with no pain. Cystoid macular edema is a well-known complication affecting vision adversely in late stages. The diagnosis is challenging, and prognosis is variable. While corticosteroids are the mainstay of therapy, recalcitrant or recurrent cases need immunosuppressive therapy.

Suggested Reading

  1. Bloch-Michel E, Nussenblatt RB. International Uveitis Study Group recommendations for the evaluation of intraocular inflammatory disease. Am J Ophthalmol. 1987;103:234–5.CrossRefPubMedGoogle Scholar
  2. Breeveld J, Rothova A, Kuiper H. Intermediate uveitis and Lyme borreliosis. Br J Ophthalmol. 1992;76:181–2.CrossRefPubMedPubMedCentralGoogle Scholar
  3. Jabs DA, Nusenblatt RB, Rosenbaum JT, Standardization of Uveitis Nomenclature (SUN) Working Group. Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop. Am J Ophthalmol. 2005;140:509–16.CrossRefPubMedGoogle Scholar
  4. Jain R, Ferrante P, Reddy GT, Lightman S. Clinical features and visual outcome of intermediate uveitis in children. Clin Exp Ophthalmol. 2005;33:22–5.CrossRefPubMedGoogle Scholar
  5. Malinowski SM, Pulido JS, Folk JC. Long-term visual outcome and complications associated with pars planitis. Ophthalmology. 1993;100:818–24.CrossRefPubMedGoogle Scholar
  6. Zierhut M, Foster CS. Multiple sclerosis, sarcoidosis and other diseases in patients with pars planitis. Dev Ophthalmol. 1992;23:41–7.CrossRefPubMedGoogle Scholar

Copyright information

© Springer (India) Pvt. Ltd. 2018

Authors and Affiliations

  1. 1.Advanced Eye CentrePost Graduate Institute of Medical Education and ResearchChandigarhIndia

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