Advertisement

Tubulointerstitial Nephritis and Uveitis

  • Muhammad Hassan
  • Aniruddha Agarwal
  • Nam V. Nguyen
  • Yasir J. Sepah
  • Quan Dong NguyenEmail author
Living reference work entry

Abstract

Tubulointerstitial nephritis and uveitis (TINU) is an autoimmune oculorenal syndrome commonly diagnosed in younger aged population. Ocular manifestations of TINU can be forerunner to the renal involvement in about one-fifth of the patients and may also occur more than 1 year after the initial renal involvement in about 5% of the patients. The characteristic ocular manifestations of TINU include sudden onset bilateral nongranulomatous anterior uveitis with occasional mild vitreous cells. However, few cases with posterior involvement have been reported in the literature. The uveitis in TINU, unlike the renal involvement which commonly resolves spontaneously, is either chronic or recurrent in nature with flares occurring for ≥10 years.

Suggested Reading

  1. Levinson RD. Tubulointerstitial nephritis and uveitis syndrome. Int Ophthalmol Clin. 2008;48(3):51–9.CrossRefGoogle Scholar
  2. Mackensen F, Billing H. Tubulointerstitial nephritis and uveitis syndrome. Curr Opin Ophthalmol. 2009;20(6):525–31.CrossRefGoogle Scholar
  3. Pakzad-Vaezi K, Pepple KL. Tubulointerstitial nephritis and uveitis. Curr Opin Ophthalmol. 2017;28(6):629–35.CrossRefGoogle Scholar
  4. Yao L, Foster CS. Tubulointerstitial nephritis and uveitis syndrome. Int Ophthalmol Clin. 2001;41(4):217–21.CrossRefGoogle Scholar

Copyright information

© Springer (India) Pvt. Ltd., part of Springer Nature 2018

Authors and Affiliations

  • Muhammad Hassan
    • 1
  • Aniruddha Agarwal
    • 3
  • Nam V. Nguyen
    • 1
  • Yasir J. Sepah
    • 1
  • Quan Dong Nguyen
    • 2
    Email author
  1. 1.Byers Eye InstituteStanford UniversityPalo AltoUSA
  2. 2.Byers Eye InstituteStanford University, Spencer Center for Vision ResearchPalo AltoUSA
  3. 3.Department of OphthalmologyAdvanced Eye Center, Post Graduate Institute of Medical Education and Research (PGIMER)ChandigarhIndia

Personalised recommendations