Encyclopedia of Parasitology

2016 Edition
| Editors: Heinz Mehlhorn

Survival Strategies, Protozoa

Reference work entry
DOI: https://doi.org/10.1007/978-3-662-43978-4_3055
Intracellular protozoans have developed different strategies to survive attacks of the host defense systems. Examples are:
  1. 1.

    Leishmania spp. invade by receptor-mediated phagocytosis, are placed inside phagolysosomes, become protected inside by lipophosphoglycan.

  2. 2.

    Trypanosoma cruzi tissue stages enter actively their host cells, lay immediately in the cytoplasm, and are protected there by a protein (C 9 cross-reactive protein, TcTox trans-sialidase).

  3. 3.

    Toxoplasma gondii tachyzoites enter actively, are situated in a fusion-resistant parasitophorous vacuole and are protected there by the excreted proteins of micronemes, rhoptries, and dense granules.


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