Perinatal Physiology

  • Carlos E. BlancoEmail author
  • Eduardo Villamor
Reference work entry


This chapter will discuss the mechanisms preparing the fetus to be born, the transition at birth, and the successful adaptation to the air-breathing world. This chapter will review the respiratory system including lung development, maturation, and role of surfactant system and the respiratory drive and chemoreceptor role and the circulatory system including fetal circulation and its changes at birth.


Fetus Fetal breathing Lung development Birth Pulmonary circulation Ductus arteriosus Control of breathing 



This chapter has been adapted from the author’s own chapter in the following publication: Copyright © 2011 From Newborn Surgery, Third Edition, by Prem Puri. Reproduced by permission of Taylor and Francis Group, LLC, a division of Informa plc.


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© Springer-Verlag GmbH Germany, part of Springer Nature 2020

Authors and Affiliations

  1. 1.Department of NeonatologyNational Maternity HospitalDublinIreland
  2. 2.Department of Pediatrics, School for Oncology and Developmental Biology (GROW)Maastricht University Medical Center (MUMC+)MaastrichtThe Netherlands

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