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Portal Hypertension

Living reference work entry
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Abstract

Portal hypertension (PHT) in children may be caused by a wide range of etiologies, including extrahepatic portal vein obstruction, biliary atresia, alpha-1-antitrypsin deficiency, and autoimmune hepatitis. PHT presents with acute gastrointestinal bleeding and/or splenomegaly or with symptoms and signs of chronic liver disease. Gastroesophageal varices and ascites are two main complications of PHT responsible for morbidity and mortality. This chapter describes the pathogenesis and management of PHT in children.

Notes

Acknowledgments

This chapter has been adapted by permission from Springer Nature: Springer-Verlag, Berlin. Pediatric Surgery. Diagnosis and Management. Portal hypertension, Stringer MD, 2009.

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Further Reading

  1. de Ville de Goyet J, D’Ambrosio G, Grimaldi C. Surgical management of portal hypertension in children. Semin Pediatr Surg. 2012;21:219–32.CrossRefGoogle Scholar
  2. Stringer MD, Oldham KT, PDE M. Pediatric surgery and urology: long term outcomes, Chapters on portal hypertension. 2nd ed. New York: Cambridge University Press; 2006. p. 491–509.CrossRefGoogle Scholar

Authors and Affiliations

  1. 1.Department of Paediatric Surgery, Wellington Children’s Hospital and Department of Paeddiatrics and Child HealthWellington School of Medicine, University of OtagoWellingtonNew Zealand

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