X-ray Fluorescence Imaging: Elemental and Chemical Speciation Mapping of Biological Systems
X-ray fluorescence imaging is a technique that can be applied to determine the microscopic localization of trace elements in biological samples.
Metal ions play a number of key roles in biology, functioning in the active sites of metalloenzymes, as structural elements of essential proteins, and additionally play a variety of physiological roles such as neurotransmitters and in the immune response. X-ray fluorescence imaging is a method that can be applied to map the microscopic localization of metals and other elements in a complex biological sample. This entry is not intended to be a comprehensive treatment across all fields, but instead seeks to illustrate the capabilities of the method relevant...
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