Supported Lipid Bilayers
Living reference work entry
Supported lipid bilayers are used in many biophysical investigations as well as in analytical devices. They are mechanically stable with defined properties, and they can be interfaced with means to monitor electric, mechanical, or diffusion-related properties (“ Lipid Lateral Diffusion”). Furthermore, supported lipid bilayers have been designed to exhibit well-defined shapes and curvature, which can be planar, spherical, or cylindrical depending on the nature of the support. They have been prepared as single bilayer deposits (Brian and McConnell 1984) or as stacks of lipid bilayers where only the outermost membranes are in contact with the solid support (Fig. 1) (Powers and Clark 1975). In the latter case, the mechanical alignment of the membrane in direct contact with the mechanical support is transmitted throughout the stack through the interaction between subsequent bilayers (Fig. 1e) (Aisenbrey et al. 2010). Supported lipid membranes come in many...
- Ivanov D, Dubreuil N, Raussens V, Ruysschaert JM, Goormaghtigh E (2004) Evaluation of the ordering of membranes in multilayer stacks built on an ATR-FTIR germanium crystal with atomic force microscopy: the case of the H(+), K(+)-ATPase-containing gastric tubulovesicle membranes. Biophys J 87:1307–1315CrossRefGoogle Scholar
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