Coriander (Coriandrum sativum L.): Bioactive Molecules and Health Effects

  • Muhammad Jawad Iqbal
  • Masood Sadiq Butt
  • Hafiz Ansar Rasul SuleriaEmail author
Reference work entry
Part of the Reference Series in Phytochemistry book series (RSP)


In recent times, the advancement in the knowledge regarding health perspectives of numerous micronutrients like carotenoids, anthocyanins, flavonoids, minerals, and vitamins at molecular level along with the findings of epidemiological studies has opened a new horizon in the field of nutrition. In this regard, various plant sources including herbs and spices exhibit high antioxidant activity owing to rich phytochemistry. Among herbs, coriander (locally known as “dhanya”) is known for its therapeutic properties in the Indo-Pak subcontinent. It is one of the widely cultivated herbs and native to North Africa, Southern Europe, and southwestern Asia. Scientifically, coriander (Coriandrum sativum L.) belongs to the Umbelliferae (Apiaceae) family. The herb portion consists of leaves and stems. The herbs and seeds of coriander are being excessively used in the traditional culinary owing to its pleasant color and flavor. Coriander seeds are commonly used in spices, and its utilization is popular in the Mediterranean region. Furthermore, coriander seeds are added in the preparation of curry and traditional cuisines in south Asian region. Coriander leaves also possess unique aroma and commonly used to garnish the dish before serving. Leaves are also vastly utilized as a vital constituent in Vietnamese and Thai cuisine. Apart from appealing aroma, seeds and leaves are also known for their therapeutic potential in the Ayurvedic medicine since ages. Coriander has significant anti-inflammatory, hypoglycemic, and hypocholesterolemic potential. Alongside, it is also effective in mitigating gastrointestinal complications. Besides, essential oils extracted from coriander leaves and seeds are used in food applications, fish and meat products, pickles, beverages, and sweets owing to its pleasant aroma and high free radical scavenging activity. Coriander seeds and herbs also possess significant hepatoprotective and antioncogenic potential.


Coriander Flavonoids Polyphenols Hypoglycemia Hepatoprotective Hypocholesterolemic 



Alkaline phosphatase


Alanine transaminase


Aspartate transaminase


Box-Behnken design




Carbon tetrachloride


Catechin equivalent


Coriandrum sativum




Dry weight


Ferric reducing antioxidant power


Gallic acid equivalent




Reduced glutathione


Glutathione peroxidase


Heme oxygenase


Half maximal inhibitory concentration


Lipid peroxidation


Maharasnadhi Quather


Nicotinamide adenine dinucleotide phosphate


Nitric oxide


Parts per million


Peroxidase enzyme


Reactive oxygen species


Response surface methodology


Supercritical fluid extraction


Superoxide dismutase


Subcritical water extraction


Thiobarbituric acid reactive substances


Trolox equivalent


Trolox equivalent antioxidant capacity


Thin-layer chromatography


Total phenolic content



The authors are thankful to Functional and Nutraceutical Food Research Section, National Institute of Food Science and Technology, University of Agriculture, Faisalabad, Pakistan. The project was partially supported by Higher Education Commission, Pakistan, under Pak-US Science and Technology Cooperation Program Phase IV with project entitled “Establishment of Functional and Nutraceutical Food Research Section at the National Institute of Food Science and Technology, University of Agriculture, Faisalabad, Pakistan.”


  1. 1.
    Jayasekera H, Carter G, Clover K (2011) Comparison of the composite international diagnostic interview (cidi-auto) with clinical diagnosis in a suicidal population. Arch Suicide Res 15(1):43–55PubMedCrossRefGoogle Scholar
  2. 2.
    Sharma MM, Sharma RK (2012) Coriander. In: Peter KV (ed) Handbook of herbs and spices, 2nd edn, vol 1. Woodhead Publishing series in food science, technology, and nutrition, no. 227. Woodhead Publishing Limited, Cambridge, UK, pp 216–249Google Scholar
  3. 3.
    Laribi B, Kouki K, M’Hamdi M, Bettaie T (2015) Coriander (Coriandrum sativum L.) and its bioactive constituents. Fitoterapia 103:9–26PubMedCrossRefGoogle Scholar
  4. 4.
    Melo EA, Filho JM, Guerra NB (2005) Characterization of antioxidant compounds in aqueous coriander extract (Coriandrum sativum L.) LWT-Food Sci Technol 38:15–19CrossRefGoogle Scholar
  5. 5.
    Singh G, Maurya S, De Lampasona MP, Catalan CAN (2006) Studies on the essential oils, Part 41. Chemical composition, antifungal, antioxidant and sprout suppressant activities of coriander (Coriandrum sativum) essential oil and its oleoresin. Flavour Frag J 21:472–479CrossRefGoogle Scholar
  6. 6.
    Sriti J, Neffati M, Msaada K, Talou T, Marzouk B (2013) Biochemical characterization of coriander cakes obtained by extrusion. J Chem. Scholar
  7. 7.
    Kamat A, Pingulkar K, Bhushan B, Gholap A, Thomas P (2003) Potential application of low dose gamma irradiation to improve the microbiological safety of fresh coriander leaves. Food Cont 4:529–537CrossRefGoogle Scholar
  8. 8.
    Sahib NG, Anwar F, Gilani AH, Hamid AA, Saari N, Alkharfy KM (2012) Coriander (Coriandrum sativum L.): a potential source of high-value components for functional foods and nutraceuticals-a review. Phytother Res 27(10):1439–1456PubMedGoogle Scholar
  9. 9.
    Msaada K, Jemia MB, Salem N, Bachrouch O, Sriti J, Tammar S, Bettaieb I, Jabri I, Kefi S, Limam F, Marzouk B (2013) Antioxidant activity of methanolic extracts from three coriander (Coriandrum sativum L.) fruit varieties. Arab J Chem. (in press)CrossRefGoogle Scholar
  10. 10.
    Coskuner Y, Karababa E (2007) Physical properties of coriander seeds (Coriandrum sativum L.) J Food Eng 80:408–416CrossRefGoogle Scholar
  11. 11.
    Ramadan MF, Mörsel JT (2002) Oil composition of coriander (Coriandrum sativum L.) fruit-seeds. Eur Food Res Technol 215:204s–2049CrossRefGoogle Scholar
  12. 12.
    Ozcan MM, Unver A, Ucar T, Arslan D (2008) Mineral content of some herbs and herbal teas by infusion and decoction. Food Chem 106:1120–1127CrossRefGoogle Scholar
  13. 13.
    Al-Bataina BA, Masiat AO, Al-Kofahi MM (2003) Element analysis and biological studies on ten oriental spices using XRF and Ames test. Trace Elem Med Biol 17(2):85–90CrossRefGoogle Scholar
  14. 14.
    Telci I, TO G, Sahbaz N (2006) Yield, essential oil content and composition of Coriandrum sativum varieties (var. vulgare Alef and var. microcarpum DC.) grown in two different locations. J Essent Oil Res 18:189–193CrossRefGoogle Scholar
  15. 15.
    Bandoni AL, Mizrahi I, Juarez MA (1998) Composition and quality of essential oil of coriander (Coriandrum sativum L.) from Argentina. J Essent Oil Res 10:581–584CrossRefGoogle Scholar
  16. 16.
    Rastogi RP, Mehrotra BN (1993) Compendium of Indian medicinal plants, vol II. CDRI, LucknowGoogle Scholar
  17. 17.
    Nazrul M, Bhuiyan I, Begum J, Sultana M (2009) Chemical composition of leaf and seed essential oil of Coriandrum sativum L. from Bangladesh. Bangladesh J Pharmacol 4:150–153Google Scholar
  18. 18.
    Zheljazkov VD, Pickett KM, Caldwell CD, Pincock JA, Roberts JC, Mapplebeck L (2008) Cultivar and sowing date effects on seed yield and oil composition of coriander in Atlantic Canada. Ind Crop Prod 28:88–94CrossRefGoogle Scholar
  19. 19.
    Msaada K, Hosni K, Ben Taarit M, Chahed T, Kchouk ME, Marzouk B (2007) Changes on essential oil composition of coriander (Coriandrum sativum L.) fruits during three stages of maturity. Food Chem 102:1131–1134CrossRefGoogle Scholar
  20. 20.
    Ghani A (2003) Medicinal plants of Bangladesh: chemical constituents and uses, 2nd edn. Asiatic Society of Bangladesh, OhakaGoogle Scholar
  21. 21.
    Sahib NG, Anwar F, Gilani AH, Abdul-Hamid A, Saari N, Alkharfy KM (2013) Coriander (Coriandrum sativum L.): a potential source of high-value components for functional foods and nutraceuticals – a review. Phytother Res 27(10):1439–1456PubMedGoogle Scholar
  22. 22.
    Bhat S, Kaushal P, Kaur M, Sharma HK (2014) Coriander (Coriandrum sativum L.): processing, nutritional and functional aspects. African J Plant Sci 8(1):25–33CrossRefGoogle Scholar
  23. 23.
    Gil A, De La Fuente EB, Lenardis AE, López Pereira M, Suárez SA, Bandoni A (2002) Coriander essential oil composition from two genotypes grown in different environmental conditions. J Agric Food Chem 50:2870–2877PubMedCrossRefGoogle Scholar
  24. 24.
    Verma A, Pandeya SN, Yadav SK, Singh S, Soni P (2011) A review on Coriandrum sativum (Linn.): an ayurvedic medicinal herb of happiness. J Adv Pharm Healthc Res 1(3):28–48Google Scholar
  25. 25.
    Khan SW, Khatoon S (2008) Ethnobotanical studies on some useful herbs of Haramosh and Bugrote valleys in Gilgit, northern areas of Pakistan. Pak J Bot 40(1):43–58Google Scholar
  26. 26.
    Ugulu I, Baslar S, Yorek N, Dogan Y (2009) The investigation and quantitative ethnobotanical evaluation of medicinal plants used around Izmir province, Turkey. J Med Plant Res 3(5):345–367Google Scholar
  27. 27.
    Platel K, Srinivasan K (2004) Digestive stimulant actions of spices: a myth or reality? Indian J Med Res 119:167–179PubMedGoogle Scholar
  28. 28.
    Al Rowais NA (2002) Herbal medicine in the treatment of diabetes mellitus. Saudi Med J 23(11):1327–1331Google Scholar
  29. 29.
    Otoom SA, Al-Safi SA, Kerem ZK, Alkofahi A (2006) The use of medicinal herbs by diabetic Jordanian patients. J Herb Pharmacother 6(2):31–41PubMedCrossRefGoogle Scholar
  30. 30.
    Tahraoui A, El Hilaly J, Israili ZH, Lyoussi B (2007) Ethnopharmacological survey of plants used in traditional treatment of hypertension and diabetes in southeastern Morocco (Errachidia province). J Ethnopharmacol 110(1):105–117PubMedCrossRefGoogle Scholar
  31. 31.
    Jelodar G, Mohsen M, Shahram S (2007) Effect of walnut leaf, coriander and pomegranate on blood glucose and histopathology of pancreas of alloxan induced diabetic rats. Afr J Tradit Complement Altern Med 4(3):299–305PubMedPubMedCentralCrossRefGoogle Scholar
  32. 32.
    Eddouks M, Maghrani A, Lemhadri ML, Ouahidi L, Jouad H (2002) Ethnopharmacological survey of medicinal plants used for the treatment of diabetes mellitus, hypertension and cardiac diseases in the south-east region of Morocco (Tafilalet). J Ethnopharmacol 82(2–3):97–103PubMedCrossRefGoogle Scholar
  33. 33.
    Abu Rabia A (2005) Herbs as a food and medicine source in Palestine. Asian Pac J Cancer Prev 6(3):404–407PubMedGoogle Scholar
  34. 34.
    Aissaoui A, El-Hilaly J, Israili ZH, Lyoussi B (2008) Acute diuretic effect of continuous intravenous infusion of an aqueous extract of Coriandrum sativum L. in anesthetized rats. J Ethnopharmacol 115(1):89–95PubMedCrossRefGoogle Scholar
  35. 35.
    Thabrew MI, Dharmasiri MG, Senaratne L (2003) Anti-inflammatory and analgesic activity in the polyherbal formulation Maharasnadhi Quathar. J Ethnopharmacol 85(2–3):261–267PubMedCrossRefGoogle Scholar
  36. 36.
    Emamghoreishi M, Heidari-Hamedani G (2004) Anticonvulsant effect of extract and essential oil of Coriandrum sativum seed in conscious mice. Iran J Pharm Res 3(1):71Google Scholar
  37. 37.
    Emamghoreishi M, Heidari-Hamedani G (2006) Sedative-hypnotic activity of extracts and essential oil of coriander seeds. Iran J Med Sci 31(1):22–27Google Scholar
  38. 38.
    Chaudry NM, Tariq P (2006) Bactericidal activity of black pepper, bay leaf, aniseed and coriander against oral isolates. Pak J Pharm Sci 19(3):214–218Google Scholar
  39. 39.
    Msaada K, Jemia MB, Salem N, Bachrouch O, Sriti J, Tammar S, Bettaieb I, Jabri I, Kefi S, Limam F, Marzouk B (2017) Antioxidant activity of methanolic extracts from three coriander (Coriandrum sativum L.) fruit varieties. Arab J Chem 10(2):S3176-S3183CrossRefGoogle Scholar
  40. 40.
    Neffati M, Sriti J, Hamdaoui G, Kchouk ME, Marzouk B (2011) Salinity impact on fruit yield, essential oil composition and antioxidant activities of Coriandrum sativum fruit extracts. Food Chem 124:221–225CrossRefGoogle Scholar
  41. 41.
    Sriti J, Wannes WA, Talou T, Vilarem G, Marzouk B (2011) Chemical composition and antioxidant activities of Tunisian and Canadian Coriander (Coriandrum sativum L.) Fruit. J Essen Oil Res 23:7–15CrossRefGoogle Scholar
  42. 42.
    Wangensteen H, Samuelsen AB, Malterud KE (2004) Antioxidant activity in extracts from coriander. Food Chem 88:293–297CrossRefGoogle Scholar
  43. 43.
    Barros L, Dueňas M, Dias MI, Sousa MJ, Santos-Buelga C, Ferreira ICFR (2012) Phenolic profiles of in vivo and in vitro grown Coriandrum sativum L. Food Chem 132(2):841–848CrossRefGoogle Scholar
  44. 44.
    Kandlakunta B, Rajendran A, Thingnganing L (2008) Carotene content of some common (cereals, pulses, vegetables, spices and condiments) and unconventional sources of plant origin. Food Chem 106:85–89CrossRefGoogle Scholar
  45. 45.
    Ravi R, Prakash M, Bhatt KK (2006) Aroma characterization of coriander (Coriandrum sativum L.) oil samples. Eur Food Res Technol 6:425–427Google Scholar
  46. 46.
    Msaada K, Ben Taarit M, Hosni K, Hammami M, Marzouk B (2009) Regional and maturational effects on essential oils yields and composition of coriander (Coriandrum sativum L.) fruits. Sci Hortic 122:116–124CrossRefGoogle Scholar
  47. 47.
    Nejad ES, Hadian J, Ranjbar H (2010) Essential oil compositions of different accessions of Coriandrum sativum L. from Iran. Nat Prod Res 24(14):1287–1294CrossRefGoogle Scholar
  48. 48.
    Bhuiyan NI, Begum J, Sultana M (2009) Chemical composition of leaf and seed essential oil of Coriandrum sativum L. from Bangladesh. Bangladesh J Pharmacol 4:150–153CrossRefGoogle Scholar
  49. 49.
    Anwar F, Sulman M, Hussain AI, Saari N, Iqbal C, Rashid U (2011) Physicochemical composition of hydro-distilled essential oil from coriander (Coriandrum sativum L.) seeds cultivated in Pakistan. J Med Plant Res 5(15):3537–3544Google Scholar
  50. 50.
    Zoubiri S, Baaliouamer A (2010) Essential oil composition of Coriandrum sativum seed cultivated in Algeria as food grains protectant. Food Chem 122:1226–1228CrossRefGoogle Scholar
  51. 51.
    De Figueiredo RO, Marques MOM, Nakagawa J, Ming LC (2004) Composition of coriander essential oil from Brazil. Acta Hortic 629:135–137CrossRefGoogle Scholar
  52. 52.
    Msaada K, Hosni K, Ben Taarit M, Hammami M, Marzouk B (2009) Effects of growing region and maturity stages on oil yield and fatty acid composition of coriander (Coriandrum sativum L.) fruit. Sci Hortic 120:525–531CrossRefGoogle Scholar
  53. 53.
    Neffati M, Marzouk B (2008) Changes in essential oil and fatty acid composition in coriander (Coriandrum sativum L.) leaves under saline conditions. Ind Crop Prod 28:137–142CrossRefGoogle Scholar
  54. 54.
    Neffati M, Marzouk B (2009) Roots volatiles and fatty acids of coriander (Coriandrum sativum L.) grown in saline medium. Acta Physiol Plant 31:455–461CrossRefGoogle Scholar
  55. 55.
    Ghamarnia H, Daichin S (2013) Effect of different water stress regimes on different Coriander (Coriander sativum L.) parameters in a semi-arid climate. Int J Agron Plant Prod 4(4):822–832Google Scholar
  56. 56.
    Hassan FAS, Ali EF (2014) Impact of different water regimes based on class-A pan on growth, yield and oil content of Coriandrum sativum L. plant. J Saudi Soc Agric Sci 13(2):155–161Google Scholar
  57. 57.
    Benyoussef EH, Saibi S (2013) Influence of essential oil composition on water distillation kinetics. Flavour Fragr J 28(5):300–308CrossRefGoogle Scholar
  58. 58.
    Kosar M, Ozek T, Goger F, Kurkcuoglu M, Baser KHC (2005) Comparison of microwave assisted hydrodistillation and hydrodistillation methods for the analysis of volatile secondary metabolites. Pharm Biol 43(6):491–495CrossRefGoogle Scholar
  59. 59.
    Grosso C, Ferraro V, Figueiredo AC, Barroso JG, Coelho JA, Palavra AM (2008) Supercritical carbon dioxide extraction of volatile oil from Italian coriander seeds. Food Chem 111(1):197–203CrossRefGoogle Scholar
  60. 60.
    Turek C, Stintzing FC (2012) Stability of essential oils: a review. Compr Rev Food Sci Food Saf 12:40–53CrossRefGoogle Scholar
  61. 61.
    Kitajima J, Ishikawa T, Fujimatu E, Kondho K, Takayanagi T (2003) Glycosides of 2 C-methyl-d-erythritol from the fruits of anise, coriander and cumin. Phytochemistry 62:115–120PubMedCrossRefGoogle Scholar
  62. 62.
    Sriti J, Talou T, Wannes WA, Cerny M, Marzouk B (2009) Essential oil, fatty acid and sterol composition of Tunisian coriander fruit different parts. J Sci Food Agric 89:1659–1664CrossRefGoogle Scholar
  63. 63.
    Sriti J, Wannes WA, Talou T, Mhamdi B, Handaoui G, Marzouk B (2010a) Lipid fatty acid and tocol distribution of coriander fruits’ different parts. Ind Crop Prod 31:294–300CrossRefGoogle Scholar
  64. 64.
    Sriti J, Wannes WA, Talou T, Mhamdi B, Cerny M, Marzouk B (2010b) Lipid profile of Tunisian coriander (Coriandrum sativum) seed. J Am Chem Soc 87:395–400Google Scholar
  65. 65.
    Matasyoh JC, Maiyo ZC, Ngure RM, Chepkorir R (2009) Chemical composition and antimicrobial activity of the essential oil of Coriandrum sativum. Food Chem 113(2):526–529CrossRefGoogle Scholar
  66. 66.
    Nambiar VS, Daniel M, Guin P (2010) Characterization of polyphenols from coriander leaves (Coriandrum sativum), red amaranthus (A. paniculatus) and green amaranthus (A. frumentaceus) using paper chromatography and their health implications. J Herb Med Toxicol 4(1):173–177Google Scholar
  67. 67.
    Oganesyan ET, Nersesyan ZM, Parkhomenko AY (2007) Chemical composition of the above-ground part of Coriandrum sativum. Pharm Chem J 41(3):30–34CrossRefGoogle Scholar
  68. 68.
    Rahimi AR, Babaei S, Kambiz M, Asad R, Sheno A (2013) Anthocyanin content of coriander leaves as affected by salicylic acid and nutrients application. Int J Biosci 3(2):141–145CrossRefGoogle Scholar
  69. 69.
    Begnami AF, Duarte MCT, Furletti V, Rehder VLG (2010) Antimicrobial potential of Coriandrum sativum L. against different Candida species in vitro. Food Chem 118:74–77CrossRefGoogle Scholar
  70. 70.
    Padalia RC, Karki N, Sah AN, Verma RS (2011) Volatile constituents of leaf and seed essential oil of Coriandrum sativum L. J Essent Oil Bear Plants 14(5):610–616CrossRefGoogle Scholar
  71. 71.
    Chung IM, Ahmad A, Kim SJ, Naik PM, Nagella P (2012) Composition of the essential oil constituents from leaves and stems of Korean Coriandrum sativum and their immunotoxicity activity on the Aedes aegypti L. Immunopharmacol Immunotoxicol 34(1):152–156PubMedCrossRefGoogle Scholar
  72. 72.
    Guerra N, Melo E, Filho J (2005) Characterization of antioxidant compounds in etheric coriander extract (Coriandrum sativum L.) J Food Compos Anal 18:193–199CrossRefGoogle Scholar
  73. 73.
    Divya P, Puthusseri B, Neelwarne B (2012) Carotenoid content, its stability during drying and the antioxidant activity of commercial coriander (Coriandrum sativum L.) varieties. Food Res Int 45(1):342–350CrossRefGoogle Scholar
  74. 74.
    Pavlic B, Vidovic S, Vladic J, Radosavljevic R, Zekovic Z (2015) Isolation of coriander (Coriandrum sativum L.) essential oil by green extractions versus traditional techniques. J Supercrit Fluids 99:23–28CrossRefGoogle Scholar
  75. 75.
    Eikani MH, Golmohammad F, Rowshanzamir S (2007) Subcritical water extraction of essential oils from coriander seeds (Coriandrum sativum L.) J Food Eng 80:735–740CrossRefGoogle Scholar
  76. 76.
    Kaiser A, Kammerer DR, Carle R (2013) Impact of blanching on polyphenol stability and antioxidant capacity of innovative coriander (Coriandrum sativum L.) pastes. Food Chem 140:332–339PubMedCrossRefGoogle Scholar
  77. 77.
    Pourmortazavi SM, Hajimirsadeghi SS (2007) Supercritical fluid extraction in plant essential and volatile oil analysis. J Chromatograph 1163:2–24CrossRefGoogle Scholar
  78. 78.
    Brunner G (2014) Hydrothermal and supercritical water properties. In: Erdogan K (ed) Supercritical fluid science and technology series, vol 5. Elsevier, The Boulevard, Langford Lane, Kidlington, OxfordGoogle Scholar
  79. 79.
    Teo CC, Tan SN, Hong Yong JW, Hew CS, Ong ES (2010) Pressurized hot water extraction. J Chromatograph A 1217:2484–2494. (Review)CrossRefGoogle Scholar
  80. 80.
    Saim N, Osman R, Yasin WAHM, Hamid RD (2008) Subcritical water extraction of essential oil from coriander (Coriandrum sativum L.) seeds. Malaysian J Anal Sci 12:22–24Google Scholar
  81. 81.
    Grosso C, Figueiredo AC, Burillo J, Mainar AM, Urieta JS, Barroso JG, Coelho JA, Palavra AMF (2009) Enrichment of the thymoquinone content in volatile oil from Satureja montana using supercritical fluid extraction. J Sep Sci 32:328–334PubMedCrossRefGoogle Scholar
  82. 82.
    Vidovic S, Zekovic Z, Morasanovic B, Pandurevic M, Vladic J (2014) Influence of pre-treatments on yield, chemical composition and antioxidant activity of Satureja montana extracts obtained by supercritical carbon dioxide. J Supercrit Fluids.
  83. 83.
    Illes V, Daood HG, Perneczki S, Szokonya L, Then M (2000) Extraction of coriander seed oil by CO2 and propane at super- and subcritical conditions. J Supercrit Fluids 17:177–186CrossRefGoogle Scholar
  84. 84.
    Mhemdi H, Rodier E, Kechaou N, Fages J (2011) A supercritical tunable process for the selective extraction of fats and essential oil from coriander seeds. J Food Eng 105:609–616CrossRefGoogle Scholar
  85. 85.
    Zekovic Z, Busic A, Komes D, Vladic J, Adamovic D, Pavlic B (2015) Coriander seeds processing: sequential extraction of non-polar and polar fractions using supercritical carbon dioxide extraction and ultrasound-assisted extraction. Food Bioprod Process 95:218–227CrossRefGoogle Scholar
  86. 86.
    Zekovic Z, Pavlic B, Cvetanovic A, Durovic S (2016) Supercritical fluid extraction of coriander seeds: process optimization, chemical profile and antioxidant activity of lipid extracts. Ind Crop Prod 94:353–362CrossRefGoogle Scholar
  87. 87.
    Zekovic Z, Kaplan M, Pavlic B, Olgun EO, Vladic J, Canli O, Vidovic S (2016) Chemical characterization of polyphenols and volatile fraction of coriander (Coriandrum sativum L.) extracts obtained by subcritical water extraction. Ind Crop Prod 87:54–63CrossRefGoogle Scholar
  88. 88.
    McDonald S, Prenzler PD, Antolovich M, Robards K (2001) Phenolic content and antioxidant activity of olive extracts. Food Chem 73:73–84CrossRefGoogle Scholar
  89. 89.
    Amagata T, Whitman S, Johnson TA, Stessman CC, Loo CP, Lobkovsky E, Clardy J, Crews P, Holman TR (2003) Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases. J Natur Prod 66:230–235CrossRefGoogle Scholar
  90. 90.
    El-Massry KF, El-Ghorab AH, Farouk A (2002) Antioxidant activity and volatile components of Egyptian Artemisia judaica L. Food Chem 79:331–336CrossRefGoogle Scholar
  91. 91.
    Kulisic T, Radonic A, Katalinic V, Milos M (2004) Use of different methods for testing antioxidative activity of oregano essential oil. Food Chem 85:633–640CrossRefGoogle Scholar
  92. 92.
    Pernice R, Borriello G, Ferracane R, Borrelli RC, Cennamo F, Ritieni A (2009) Bergamot: a source of natural antioxidants for functionalized fruit juices. Food Chem 112:545–550CrossRefGoogle Scholar
  93. 93.
    Schieber A, Stintzing FC, Carle R (2001) By-products of plant food processing as a source of functional compounds – recent developments. Trends Food Sci Technol 12:401–413CrossRefGoogle Scholar
  94. 94.
    Siró I, Kápolna E, Kápolna B, Lugasi A (2008) Functional food. Product development, marketing and consumer acceptance-A review. Appetite 51(3):456–467PubMedCrossRefGoogle Scholar
  95. 95.
    Yoshikawa T, Naito Y (2002) What is oxidative stress? J Japan Med Assoc 45(7):271–276Google Scholar
  96. 96.
    Charles W, Paul K (2009) Sugar metabolism. Microsoft® Encarta® 2009 [DVD]. Microsoft Corporation, RedmondGoogle Scholar
  97. 97.
    Valko M, Leibfritz D, Moncol J, Cronin MTD, Mazura M, Telser J (2007) Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 39:44–84PubMedCrossRefGoogle Scholar
  98. 98.
    Mitchell RN, Cotran RS (2003) Cell injury, adaptation and death. In: Kumar V, Cotran RS, Robbins SL (eds) Robbins basic pathology, 7th edn. Harcourt (India) Pvt Ltd., New Delhi, pp 3–33Google Scholar
  99. 99.
    Rajeshwari CU, Andallu B (2011) Oxidative stress in NIDDM patients: influence of coriander (Coriandrum sativum) seeds. Res J Pharm Biol Chem Sci 2(1):31–41Google Scholar
  100. 100.
    Aissaoui A, Zizi S, Israili ZH, Lyoussia B (2011) Hypoglycemic and hypolipidemic effects of Coriandrum sativum L. in Meriones shawi rats. J Ethnopharmacol 137:652–661PubMedCrossRefGoogle Scholar
  101. 101.
    Deepa B, Anuradha CV (2011) Antioxidant potential of Coriandrum sativum L. seed extract. Indian J Exp Biol 49:30–38PubMedGoogle Scholar
  102. 102.
    Eidi M, Eidi A, Saeidi A, Molanaei S, Sadeghipour A, Bahar M, Bahar K (2009) Effect of Coriander Seed (Coriandrum sativum L.) Ethanol Extract on Insulin Release from Pancreatic Beta Cells in Streptozotocin-induced Diabetic Rats. Phytother Res 23:404–406PubMedCrossRefGoogle Scholar
  103. 103.
    Gray AM, Flatt PR (1999) Insulin-releasing and insulin-like activity of the traditional anti-diabetic plant Coriandrum sativum (coriander). Br J Nutr 81:203–209PubMedCrossRefGoogle Scholar
  104. 104.
    Redmond WA (2009) Liver. Microsoft® Encarta® 2009 [DVD]. Microsoft Corporation, RedmondGoogle Scholar
  105. 105.
    Samojlik I, Lakic N, Mimica-Dukic N, Dakovic-Svajcer K, Bozin B (2010) Antioxidant and hepatoprotective potential of essential oils of coriander (Coriandrum sativum L.) and caraway (Carum carvi L.) (Apiaceae). J Agric Food Chem 58:8848–8853PubMedCrossRefGoogle Scholar
  106. 106.
    Kassem SS, Abdel-Kader MM, Al-Sayed EM, El-Din S, El-Hawary MHAZ, Haggag MM (2014) Modulatory effects of aerial parts of Coriandrum sativum L. On carbon-tetrachlorid induced hepatorenal toxicity. Global Veterinaria 12(4):523–531Google Scholar
  107. 107.
    Moustafa AHA, Ali EMM, Moselhey SS, Tousson E, El-Said KS (2012) Effect of coriander on thioacetamide-induced hepatotoxicity in rats. Toxicol Ind Health 30(7):621–9PubMedCrossRefGoogle Scholar
  108. 108.
    Sreelatha S, Padma PR, Umadevi M (2009) Protective effects of Coriandrum sativum extracts on carbon tetrachloride-induced hepatotoxicity in rats. Food Chem Toxicol 47:702–708PubMedCrossRefGoogle Scholar

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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Muhammad Jawad Iqbal
    • 1
  • Masood Sadiq Butt
    • 1
  • Hafiz Ansar Rasul Suleria
    • 2
    • 3
    Email author
  1. 1.National Institute of Food Science and Technology, Faculty of Food, Nutrition and Home SciencesUniversity of AgricultureFaisalabadPakistan
  2. 2.UQ School of Medicine, Translational Research InstituteThe University of QueenslandBrisbaneAustralia
  3. 3.Department of Food, Nutrition, Dietetics and HealthKansas State UniversityManhattanUSA

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