Electrolytic Abnormalities Related to Sodium in Critically Ill Cancer Patients

  • Agamenón Quintero
  • Jorge RacedoEmail author
  • Carlos Andrés Pérez Acosta
  • Sandra Aruachán
Reference work entry


Sodium homeostasis and water balance are vital for a critically ill patient with cancer. Hypernatremia and hyponatremia are metabolic emergencies in the oncologic ICU associated with higher mortality rates and prolonged length of stay. Patients with cancer are susceptible to have variations in plasma osmolality leading to those conditions. Drugs, tumor-related injuries, metastasis, surgery, chemotherapy and radiotherapy, and other pathological conditions predispose to the dysregulation of that narrow balance. Intensivists and oncologist must assess the volume status and the plasma and urine osmolality carefully to avoid life-threatening conditions leading to neurological compromise and even death. Hypernatremia and hyponatremia are commonly found in the ICU wards, so the therapeutic workup should include special attention to these electrolytic disturbances.


Hypernatremia Hyponatremia Intensive critical care Oncologic emergency Renal insufficiency SIADH Sodium homeostasis 


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Agamenón Quintero
    • 1
  • Jorge Racedo
    • 1
    Email author
  • Carlos Andrés Pérez Acosta
    • 1
  • Sandra Aruachán
    • 2
  1. 1.Department of Critical Care MedicineInstituto Médico de Alta Tecnología IMAT OncomedicaMonteríaColombia
  2. 2.Department of Clinical ResearchInstituto Médico de Alta Tecnología IMAT OncomedicaMonteríaColombia

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